URB597
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- CAS-Nr.
- 546141-08-6
- Englisch Name:
- URB597
- Synonyma:
- URB597 (KDS-4103);3-(3-carbaMoylphenyl)phenyl N-cyclohexylcarbaMate;URB597;CS-115;KDS 4103;URB 597 NEW;URB597 powder;URB 597, >=98%;APD597(URB597);FAAH inhibitor
- CBNumber:
- CB4331788
- Summenformel:
- C20H22N2O3
- Molgewicht:
- 338.4
- MOL-Datei:
- 546141-08-6.mol
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URB597 Eigenschaften
- Siedepunkt:
- 533.2±50.0 °C(Predicted)
- Dichte
- 1.23
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: ~14 mg/mL, soluble
- Aggregatzustand
- powder
- pka
- 11.74±0.20(Predicted)
- Farbe
- white
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
- InChI
- 1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
- InChIKey
- ROFVXGGUISEHAM-UHFFFAOYSA-N
- SMILES
- NC(=O)c1cccc(c1)-c2cccc(OC(=O)NC3CCCCC3)c2
URB597 Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R50/53:Sehr giftig für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S60:Dieses Produkt und sein Beh?lter sind als gef?hrlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Allgemeine Beschreibung
URB597 binds to active sites of fatty acid amide hydrolases and inhibits their activity. URB597 alters expression of tyrosine hydroxylase and interacts with abnormal-cannabidiol (Abn-CBD) and peroxisome proliferator-activated receptors (PPARs). URB597 elicits antinociception property via cannabinoid receptor by maintaining endocannabinoid anandamide (AEA) levels. URB597 reduces abnormal hyperactivity in neurons and could be for treatment of seizures and improving synaptic plasticity.
Biochem/physiol Actions
Potent, selective fatty acid amide hydrolase (FAAH) inhibitor.
URB597 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
URB597 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 182)Lieferanten
546141-08-6()Verwandte Suche:
- N-Cyclohexylcarbamic acid 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester
- KDS 4103
N-Cyclohexylcarbamic acid 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester
- N-Cyclohexylcarbamic acid 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester URB 597 KDS 4103
- URB 597, >=98%
- CarbaMic acid,N-cyclohexyl-, 3'-(aMinocarbonyl)[1,1'-biphenyl]-3-yl ester
- APD597(URB597)
- FAAH INHIBITOR II
- CYCLOHEXYLCARBAMIC ACID 3'-CARBAMOYL-BIPHENYL-3-YL ESTER
- 3'-CARBAMOYL-BIPHENYL-3-YL-CYCLOHEXYLCARBAMATE
- (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate
- KDS 4103
- URB597
- N-cyclohexylcarbamic acid [3-(3-carbamoylphenyl)phenyl] ester
- URB 597 NEW
- FAAH inhibitor
- KDS-4103;URB-597;FAAH INHIBITOR II
- FAAH Inhibitor II - CAS 546141-08-6 - Calbiochem
- CS-115
- URB597; KDS-4103; URB 597; KDS 4103; KDS4103
- Cyclohexylcarbamic acid 3'-(Aminocarbonyl)-[1,1'-biphenyl]-3-yl ester
- URB597 USP/EP/BP
- URB597 powder
- TIANFU-CHEM URB597 546141-08-6
- FAAH Inhibitor II URB597 URB-597
- 3'-(Aminocarbonyl)[1,1'-biphenyl]-3-yl N-cyclohexylcarbamate
- KDS4103,KDS-4103/URB597
- 3'-Carbamoyl-[1,1'-biphenyl]-3-yl cyclohexylcarbamate
- 3’-(3-aminocarbonyl)[1,1’-biphenyl]-3-yl)-cyclohexylcarbamat
- URB-597, 10 mM in DMSO
- 3'-(Aminocarbonyl)-biphenyl-3-yl N-cyclohexylcarbamate
- 3-(3-carbaMoylphenyl)phenyl N-cyclohexylcarbaMate
- URB597 (KDS-4103)
- 546141-08-6
- C20H22N2O3
- Pharmaceutical intermediate
- Inhibitors
- HFC80014
- Inhibitor
- Chemical for Research
- Research Chemical
