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LICOCHALCONE-A

LICOCHALCONE-A Struktur
58749-22-7
CAS-Nr.
58749-22-7
Englisch Name:
LICOCHALCONE-A
Synonyma:
Glycyrrhiza chalcone A;CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;Licochalcone A-RM;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%
CBNumber:
CB5114580
Summenformel:
C21H22O4
Molgewicht:
338.4
MOL-Datei:
58749-22-7.mol

LICOCHALCONE-A Eigenschaften

Schmelzpunkt:
100°
Siedepunkt:
532.6±50.0 °C(Predicted)
Dichte
1.171±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM)
DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM)
Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM)
pka
7.82±0.15(Predicted)
Aggregatzustand
Yellow solid
Farbe
Yellow-orange
BRN 
4534154
InChI
InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
InChIKey
KAZSKMJFUPEHHW-DHZHZOJOSA-N
SMILES
C(C1=CC=C(O)C=C1)(=O)/C=C/C1=CC(C(C)(C)C=C)=C(O)C=C1OC

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 20/21/22
S-S?tze: 36/37
WGK Germany  3
RTECS-Nr. UB8755000
Speicherklasse 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral

LICOCHALCONE-A Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

Allgemeine Beschreibung

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

Biochem/physiol Actions

Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.

LICOCHALCONE-A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


LICOCHALCONE-A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 344)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618829768577
gao490372054@gamil.com China 1249 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126
info@binbobiological.com China 477 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883
niki@zlchemi.com China 7245 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-13017695106 +86-13676922317
jiuyitime@fdachem.com China 16512 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 4616 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
52513593@qq.com CHINA 2972 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
+8613815430202
sale02@cqherb.com CHINA 376 58

58749-22-7()Verwandte Suche:


  • LICOCHALCONE-A
  • (E)-3-[5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE
  • 4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone
  • 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-
  • 7-Dimethoxycoumarin
  • Licochalcone A, >=98%
  • (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Soluble LICOCHALCONE A, Liposomal LICOCHALCONE A, LICOCHALCONE A NanoEmulsion, NanoActive LICOCHALCONE A
  • Licochalcone A, >99%
  • CS-919
  • Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem
  • (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Licocgalcone-A
  • (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
  • 4,4'-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone
  • (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Licorice Chalcone A
  • Licoricchalcone A
  • Licochalcone A (10mg)
  • Licochalcone A-RM
  • Licochalcone a Powder
  • Licochalcone A, 10 mM in DMSO
  • Licochalcone A (Standard)
  • Glycyrrhiza chalcone A
  • 58749-22-7
  • 28749-22-7
  • The group of Liquorice
  • sy
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
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