LICOCHALCONE-A
- CAS No.
- 58749-22-7
- Chemical Name:
- LICOCHALCONE-A
- Synonyms
- Glycyrrhiza chalcone A;CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;Licochalcone A-RM;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%
- CBNumber:
- CB5114580
- Molecular Formula:
- C21H22O4
- Molecular Weight:
- 338.4
- MDL Number:
- MFCD01417903
- MOL File:
- 58749-22-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Licochalcone A phyproof? Reference Substance | PHL80486 | 10MG | $506 |
| Licochalcone-A, Synthetic | 435800 | 10mg | $122 |
| Licochalcone-A, Synthetic | 435800 | 50mg | $445 |
| Licochalcone A | L0261 | 5MG | $98 |
| Licochalcone A | L0261 | 25MG | $293 |
| More product size | |||
| Melting point | 100° |
|---|---|
| Boiling point | 532.6±50.0 °C(Predicted) |
| Density | 1.171±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility |
DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM) DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM) Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM) |
| pka | 7.82±0.15(Predicted) |
| form | Yellow solid |
| color | Yellow-orange |
| BRN | 4534154 |
| InChI | InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+ |
| InChIKey | KAZSKMJFUPEHHW-DHZHZOJOSA-N |
| SMILES | C(C1=CC=C(O)C=C1)(=O)/C=C/C1=CC(C(C)(C)C=C)=C(O)C=C1OC |
| FDA UNII | JTV5467968 |
| NCI Drug Dictionary | licochalcone A |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UB8755000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
|||||||||
| NFPA 704 |
|
LICOCHALCONE-A price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL80486 | Licochalcone A phyproof? Reference Substance | 58749-22-7 | 10MG | $506 | 2026-04-30 | Buy |
| Sigma-Aldrich | 435800 | Licochalcone-A, Synthetic | 58749-22-7 | 10mg | $122 | 2026-04-30 | Buy |
| Sigma-Aldrich | 435800 | Licochalcone-A, Synthetic | 58749-22-7 | 50mg | $445 | 2026-04-30 | Buy |
| TCI Chemical | L0261 | Licochalcone A | 58749-22-7 | 5MG | $98 | 2026-04-30 | Buy |
| TCI Chemical | L0261 | Licochalcone A | 58749-22-7 | 25MG | $293 | 2026-04-30 | Buy |
LICOCHALCONE-A Chemical Properties,Uses,Production
Chemical Properties
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of licorice.
Uses
Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.
Definition
ChEBI: Licochalcone A is a member of chalcones.
General Description
An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.
Biochem/physiol Actions
Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.
LICOCHALCONE-A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 | gao490372054@gamil.com | China | 1249 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 480 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
View Lastest Price from LICOCHALCONE-A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-17 | Licochalcone A
58749-22-7
|
$50.00 | 99.65% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-02 | Licochalcone A
58749-22-7
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-05-22 | Licochalcone A
58749-22-7
|
1kg | 5% 10% 50% 98% 99% | 1000 kg | BINBO BIOLOGICAL CO.,LTD |
-
- Licochalcone A
58749-22-7
- $50.00
- 99.65%
- TargetMol Chemicals Inc.
-
- Licochalcone A
58749-22-7
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Licochalcone A
58749-22-7
- $0.00
- 5% 10% 50% 98% 99%
- BINBO BIOLOGICAL CO.,LTD
