3-isobutylglutaric acid
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- CAS-Nr.
- 75143-89-4
- Englisch Name:
- 3-isobutylglutaric acid
- Synonyma:
- 3-Isobutylpentanedioic acid;Pregabalin IMpurity I;Pregabalin Diacid-Imp;3-Isobutylglutaricaci;Isobutyl Glutaric Acid;3-isobutylglutaric acid;Pregabalin Impurity B(EP);3-ISOBUTYLPENTANEDIOC ACID;Pregabalin Impurity (IBGA);3-Isobutylglutaric acid 99%
- CBNumber:
- CB51458214
- Summenformel:
- C9H16O4
- Molgewicht:
- 188.22
- MOL-Datei:
- 75143-89-4.mol
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3-isobutylglutaric acid Eigenschaften
- Schmelzpunkt:
- 47 °C
- Siedepunkt:
- 326.2±15.0 °C(Predicted)
- Dichte
- 1.126±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- L?slichkeit
- Methanol (Slightly), Water (Slightly)
- Aggregatzustand
- Solid
- pka
- 4.19±0.10(Predicted)
- Farbe
- White to Pale Brown
- Major Application
- pharmaceutical small molecule
- InChI
- InChI=1S/C9H16O4/c1-6(2)3-7(4-8(10)11)5-9(12)13/h6-7H,3-5H2,1-2H3,(H,10,11)(H,12,13)
- InChIKey
- UATSLDZQNXAKMA-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CC(CC(C)C)CC(O)=O
3-isobutylglutaric acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Pale Brown Solid
Verwenden
An impurity of Pregabalin (P704800) with anticonvulsant properties.
Application
3-Butylglutaric acid is an intermediate in the synthesis of pregabalin.Pregabalin is approved by the United States Food and Drug Administration (FDA) to treat neuropathic pain associated with diabetic peripheral neuropathy, spinal cord injury, and postherpetic neuralgia. Pregabalin is FDA-approved for the treatment of fibromyalgia. Pregabalin also has FDA approval as adjunctive therapy for partial-onset seizures in adults with epilepsy.
Synthese
3-isobutylglutaric acid, a potential impurity which is base hydrolyzed product during Hofmann reaction, was synthesized by the reaction of (R)-(-)-3-carbamoylmethyl-5-methylhexanoic acid with excess of sodium hydroxide at elevated temperature
[1].
3-isobutylglutaric acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-isobutylglutaric acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 304)Lieferanten
75143-89-4()Verwandte Suche:
- 3-isobutylglutaric acid
- 3-(2-Methylpropyl)pentanedioic Acid
- 3-Isobutylglutaric acid 99%
- Pentanedioic acid,3-(2-Methylpropyl)-
- 3-Isobutylglutaric acid(99%)
- Pregabalin Impurity B(3-IsoButylglutaricAcid)
- Isobutyl Glutaric Acid
- Pregabalin Diacid-Imp
- Pregabalin Isobutylglutaric acid
- 3-ISOBUTYLPENTANEDIOC ACID
- Pregabalin 3-Carboxymethyl Impurity
- Isobutyl glutaric Acid(Pregablin)
- Pregabalin Diacid Impurity (Pregabalin 3-Carboxy Impurity)
- Factory supply 3-Isobutylglutaric Acid CAS 75143-89-4 high quality
- Pregabalin Impurity BQ: What is
Pregabalin Impurity B Q: What is the CAS Number of
Pregabalin Impurity B Q: What is the storage condition of
Pregabalin Impurity B Q: What are the applications of
Pregabalin Impurity B
- Pregabalin Impurity B(EP)
- 3-(2-Methylpropyl)pentanedioic Acid (3-Isobutylglutaric Acid)
- Pregabalin Impurity 2(3-Isobutylglutaric Acid)
- Pregabalin Impurity 80 (3-Isobutylglutaric Acid)
- 3-Isobutylglutaric acid or CMH Diacid
- Pregabalin Impurity (IBGA)
- Pregabalin Impurity 4/Pregabalin Impurity B
(3-Isobutylglutaric Acid)
- 3-Isobutylglutaricaci
- 3-Isobutylpentanedioic acid
- Pregabalin IMpurity I
- 75143-89-4
- Aliphatics
- Impurities
- Intermediates & Fine Chemicals
- Pharmaceuticals
- intermidiate of Pregablin
- bc0001
