一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Nisoldipine

Nisoldipine Struktur
63675-72-9
CAS-Nr.
63675-72-9
Englisch Name:
Nisoldipine
Synonyma:
Nisoldipin;1,4-DIHYDRO-2,6-DIMETHYL-4-(2-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID METHYL 2-METHYLPROPYL ESTER;Sular;NisoL;SYSCOR;Syseor;Nisocor;NORVASC;Nikameal;ZADIPINA
CBNumber:
CB5147166
Summenformel:
C20H24N2O6
Molgewicht:
388.41
MOL-Datei:
63675-72-9.mol

Nisoldipine Eigenschaften

Schmelzpunkt:
147-148°C
Siedepunkt:
503.3±50.0 °C(Predicted)
Dichte
1.205±0.06 g/cm3(Predicted)
storage temp. 
room temp
L?slichkeit
DMSO: >10mg/mL
pka
2.67±0.70(Predicted)
Aggregatzustand
powder
Farbe
yellow
Merck 
14,6565
InChI
1S/C20H24N2O6/c1-11(2)10-28-20(24)17-13(4)21-12(3)16(19(23)27-5)18(17)14-8-6-7-9-15(14)22(25)26/h6-9,11,18,21H,10H2,1-5H3
InChIKey
VKQFCGNPDRICFG-UHFFFAOYSA-N
SMILES
COC(=O)C1=C(C)NC(C)=C(C1c2ccccc2[N+]([O-])=O)C(=O)OCC(C)C
CAS Datenbank
63675-72-9(CAS DataBase Reference)
NIST chemische Informationen
Nisoldipine(63675-72-9)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 20/21/22
S-S?tze: 36
WGK Germany  3
RTECS-Nr. US7975600
HS Code  2933399090
Speicherklasse 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Nisoldipine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Nisoldipine D4 is another long-acting dihydropyridine calcium channel blocker effective in the treatment of hypertension and angina pectoris. It is reported to have little or no cardiodepressive activity and to be more effective than nifedipine in reducing blood pressure in hypertensives. Nisoldipine has also been shown to be effective in the management of congestive heart failure. Reduction in dosage is necessary in patients with hepatic, but not renal impairment.

Chemische Eigenschaften

Nisoldipine D4 is Light Tan Crystals

Verwenden

Labeled Nisoldipine, intended for use as an internal standard for the quantification of Nisoldipine by GC- or LC-mass spectrometry.

Definition

ChEBI: A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, calcium channel blocker, is used in the treatment of hypertension and angina pectoris.

Allgemeine Beschreibung

In vitro studies show that the effects ofnisoldipine, 1,4-dihydro-2, 6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinecarboxylic acid methyl 2-methylpropyl ester(Sular), on contractile processes are selective, with greaterpotency on vascular smooth muscle than on cardiac muscle.
Nisoldipine is highly metabolized, with five majormetabolites identified. As with most of the dihydropyridines,the cytochrome P450 (CYP) 3A4 isozyme is mainlyresponsible for the metabolism of nisoldipine. The majorbiotransformation pathway appears to involve the hydroxylationof the isobutyl ester side chain. This particular metabolitehas approximately 10% of the activity of the parentcompound.

Nisoldipine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Nisoldipine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 397)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29815 58
Jinan Jianfeng Chemical Co., Ltd
+86-0531-88110457 +8615562555968
info@pharmachemm.com China 310 58
Hebei Jimi Trading Co., Ltd.
+86 319 5273535
bestoneforyou@sina.com CHINA 287 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167
1026@dideu.com China 10000 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15073 58

63675-72-9()Verwandte Suche:


  • SYSCOR
  • Nisoldipine-d6
  • 3-Isobutyl 5-Methyl 2,6-diMethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid-3-methyl 5-(2-methylpropyl) ester
  • (±)-Isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate
  • 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-isobutyl ester
  • Nikameal
  • Ninobarucin
  • Nisomynard
  • 3-Methyl 5-(2-Methylpropyl) (4R)-2,6-diMethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Nisoldipine (Sular)
  • 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(2-nitrophenyl)-, 3-Methyl 5-(2-Methylpropyl)ester
  • Nisoldipine-d4
  • methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Nisoldipine, >=99%
  • 5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-met
  • hyl2-methylpropylester
  • BAYMYCARD
  • BAY K 5552
  • ZADIPINA
  • ISOBUTYL METHYL (- 1,4-DIHYDRO-2,6-DIMETHYL-4-(2-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLATE
  • Baymycard, Norvasc, Syscor, Zadipina, 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid Methyl 2-methylpropyl Ester
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, methyl 2-methylpropyl ester (9CI)
  • Nisocor
  • Sular
  • Syseor
  • 2,6-Dimethyl-4-(2-nitmphenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid methyl 2-methylpropyl ester
  • NORVASC
  • NISOLDIPINE
  • NISOLIDIPINE
  • Nisoldipine>
  • Nisoldipine Nisoldipine
  • NisoL
  • 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid Isobutyl Methyl Ester
  • Nisoldipine USP/EP/BP
  • NisoldipineQ: What is Nisoldipine Q: What is the CAS Number of Nisoldipine Q: What is the storage condition of Nisoldipine Q: What are the applications of Nisoldipine
  • hexakis(dihydrogen phosphate)
  • Nisoldipine(BAY-k 5552
  • 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-methyl ester O5-(2-methylpropyl) ester
  • NISOLDIPINE NON STERILE BULK DRUG SUBSTANCE
  • Nisoldipine - Bio-X ?
  • Nisoldipine 100 μg/mL in Methanol
  • Nisoldipinem
  • 1,4-DIHYDRO-2,6-DIMETHYL-4-(2-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID METHYL 2-METHYLPROPYL ESTER
  • Nisoldipin
  • 63675-72-9
  • C20H18N2O6D6
  • C20H24N2O6
  • Calcium channel
  • Cardiovascular APIs
  • Active Pharmaceutical Ingredients
  • All Inhibitors
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Copyright 2019 ? ChemicalBook. All rights reserved
双城市| 阿鲁科尔沁旗| 当涂县| 井陉县| 泽库县| 韶关市| 新化县| 三江| 芷江| 呼图壁县| 贵阳市| 钦州市| 广河县| 武清区| 山阳县| 钟祥市| 九龙城区| 平凉市| 临颍县| 泰州市| 远安县| 瑞金市| 电白县| 白银市| 普宁市| 西乌珠穆沁旗| 三门峡市| 顺义区| 阿巴嘎旗| 海淀区| 永州市| 余姚市| 梧州市| 昂仁县| 安泽县| 子长县| 江阴市| 金平| 广西| 英山县| 漳浦县|