3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-ar-carbonsure
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- CAS-Nr.
- 72088-94-9
- Bezeichnung:
- 3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-ar-carbonsure
- Englisch Name:
- 5(6)-Carboxyfluorescein
- Synonyma:
- 5(6)-FAM;DCFA;5(6)-Carboxyfluorescein - mixture;5(6)-Carboxyfluoresc;5(6)-CARBOXYLUORESCEIN;4(5)-CARBOXYFLUORESCEIN;5(6)-CARBOXYFLUORESCEIN;5(6)-Carboxyfluoresceine];4(5)-Carboxyfluoresceine];Fluoresceincarboxylic Acid
- CBNumber:
- CB5257173
- Summenformel:
- C42H24O14
- Molgewicht:
- 752.63
- MOL-Datei:
- 72088-94-9.mol
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3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-ar-carbonsure Eigenschaften
- Schmelzpunkt:
- 275 °C
- Siedepunkt:
- 464.9°C (rough estimate)
- Dichte
- 1.3418 (rough estimate)
- Brechungsindex
- 1.6380 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- L?slichkeit
- DMSO (Sparingly), Methanol (Slightly, Heated)
- Aggregatzustand
- Solid
- Farbe
- Light Yellow to Dark Brown
- Wasserl?slichkeit
- slightly soluble
- maximale Wellenl?nge (λmax)
- 492 nm
- ε(Extinktionskoeffizient)
- 12134 at 284nm in 0.1 M NaOH at 0.005g/L
43060 at 239nm in 0.1 M NaOH at 0.005g/L
- Major Application
- diagnostic assay manufacturing
hematology
histology
- InChIKey
- CPRVUBZYHZGASQ-UHFFFAOYSA-N
- SMILES
- C12(OC(=O)C3C=CC(C(=O)O)=CC1=3)C1=CC=C(O)C=C1OC1C=C(O)C=CC2=1.C12(OC(=O)C3C=C(C(=O)O)C=CC1=3)C1=CC=C(O)C=C1OC1C=C(O)C=CC2=1
- EPA chemische Informationen
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-ar-carbonsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36:Reizt die Augen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
5(6)-Carboxyfluorescein is a mixture of 5-carboxy and 6-carboxy derivatives of fluorescein. It is commonly used to label biomolecules through a reaction involving the carboxyl group. Unlike its succinimidyl ester derivative CFSE , 5(6)-carboxyfluorescein is membrane impermeant. As a result, it can be used in studies of membrane permeability. 5(6)-Carboxyfluorescein displays excellent fluorescence (excitation/emission at 492/514 nm, respectively), and its excitation maximum closely matches the 488 nm spectral line of argon-ion lasers.
Chemische Eigenschaften
Dark-Orange to Brown Solid
Verwenden
As a popular probe of determination of intracellular pH, 5(6)-Carboxyfluoresceincan be used as useful reagent for the preparation of hydrolytically stable fluorescent conjugates and a useful starting material for the synthesis of other fluorescein-derives reagent
Solubility in organics
5(6)-Carboxyfluorescein is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide. The solubility of 5(6)-carboxyfluorescein in these solvents is approximately 5, 0.5, and 1 mg/ml, respectively.
3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-ar-carbonsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-ar-carbonsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 279)Lieferanten
72088-94-9(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-ar-carbonsure)Verwandte Suche:
2-(2,7-Dichlor-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoesure
Xanthen
Fluorescein
Luciferase
3',6'-Dihydroxy-5(oder 6)-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on
Dinatrium-2-(3-oxo-6-oxidoxanthen-9-yl)benzoat
Dinatrium-2-(2,4,5,7-tetraiod-6-oxido-3-oxoxanthen-9-yl)benzoat
5-Carboxyfluorescein
6-Carboxyfluorescein
(1R)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-ethanol
Carboxy styrene-butadiene latex
(-)-pin-2(3)-en
(-)-pin-2(10)-en
Pin-2(10)-en
(+)-Pin-2(3)-en
Pin-2(3)-en
DL-Pin-2(3)-en
[1R-(1α,2β,4β,6α)]-2,2,7-Trimethyl-3-oxatricyclo[4.1.1.02,4]octan
- 9’-[9h]xanthene]-ar-carboxylicacid,3’,6’-dihydroxy-spiro[isobenzofuran-1(3h
- 5-(AND-6)-CARBOXYFLUORESCEIN
- 5(6)-CARBOXYFLUORESCEIN
- 4(5)-CARBOXYFLUORESCEIN
- 3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic acid
- 5(6)-CARBOXYFLUORESCEIN, FOR FLUORESCENC E
- 5(6)-CARBOXYFLUORESCEIN 99%
- 5(6)-CARBOXYLUORESCEIN
- 4(5)-Carboxyfluoresceine]
- 5(6)-Carboxyfluoresceine]
- 5(6)-CARBOXYFLUORESCEIN 95+%
- 3',6'-Dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5(6)-carboxylic acid
- 5(6)-Carboxyfluorescein, mixture of isomers, 97%
- Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic acid, 3',6'-dihydroxy-3-oxo-
- 5(6)-Carboxy-fluorescein, isomer mixture
- 5(6)-Carboxyfluorescein 5GR
- Fluoresceincarboxylic Acid
- 5(6)-Carboxyfluoresc
- 5(6)-FAM [5-(and-6)-Carboxyfluorescein] *CAS 72088-94-9*
- 5(6)-FAM [5-(and-6)-Carboxyfluorescein
- 5(6)-Carboxyfluorescein USP/EP/BP
- 3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthe...
- DCFA
- 5（6）-FAM(5(6)-carboxyfluorescein)
- 5(6)-FAM (5(6)-Carboxyfluorescein), pH-senstive fluorescent label
- 5(6)-Carboxyfluorescein, 10 mM in DMSO
- 5(6)-Carboxyfluorescein， mixture of isomers
- 3′,6′-dihydroxy-3-oxyspiro[isobenzofuran-1(3H),9′-[9H]oxyanthracene]-ar-carboxylic acid
- O-[(2R,3R,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1-yl)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-(di(propan-2-yl)amino)phosphanyl]oxyoxolan-3-yl] 1,1-dioxo-1,4-thiazinane-4-carbothioate
- 5(6)-FAM
- 5(6)-Carboxyfluorescein - mixture
- 72088-94-9
- C22H16O7
- C21H12O7
- C42H24O14
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- BioChemical
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- marker
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