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SCRIPTAID

SCRIPTAID Struktur
287383-59-9
CAS-Nr.
287383-59-9
Englisch Name:
SCRIPTAID
Synonyma:
CS-1136;GCK 1026;Scriptide;Scriptaid (GCK1026);Scriptaid, Scriptide;Scriptaid, 10 mM in DMSO;Scriptaid, HDAC inhibitor;GCK 1026; SCRIPTIDE; GCK1026; GCK-1026;6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide;1H-Benz[de]isoquinoline-2(3H)-hexanamide, N-hydroxy-1,3-dioxo-
CBNumber:
CB5504770
Summenformel:
C18H18N2O4
Molgewicht:
326.35
MOL-Datei:
287383-59-9.mol

SCRIPTAID Eigenschaften

Schmelzpunkt:
160-161 °C
Dichte
1.338±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
Soluble in DMSO (up to 4 mg/ml).
pka
9.46±0.20(Predicted)
Aggregatzustand
Yellow solid.
Farbe
White
Biologische Quelle
synthetic (organic)
Sensitive 
Light Sensitive
Stabilit?t:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChI
InChI=1S/C18H18N2O4/c21-15(19-24)10-2-1-3-11-20-17(22)13-8-4-6-12-7-5-9-14(16(12)13)18(20)23/h4-9,24H,1-3,10-11H2,(H,19,21)
InChIKey
JTDYUFSDZATMKU-UHFFFAOYSA-N
SMILES
C1(=O)C2=C3C(C=CC=C3C(=O)N1CCCCCC(NO)=O)=CC=C2

Sicherheit

WGK Germany  3
Speicherklasse 11 - Combustible Solids

SCRIPTAID Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Scriptaid is a histone deacetylase inhibitor that has an optimal concentration of 6-8 μM in a cell-based assay, is less toxic than trichostatin A, and works in a wide variety of biological systems. It induces cell cycle arrest in colon cancer cells in culture and inhibits tumor growth in vitro and in vivo. Scriptaid also facilitates the cloning of inbred mouse strains produced by somatic cell nuclear transfer.

Verwenden

Scriptaid has been used in post activation of oocytes and embryo culture.

Allgemeine Beschreibung

Scriptaid is a histone deacetylase (HDAC) inhibitor, which enhances global acetylation of histones. It improves transcriptional activity and protein expression. Scriptaid inhibits tumor growth. It decreases telomerase activity and stimulates glioma cell apoptosis.

Biologische Aktivit?t

Novel histone deacetylase inhibitor. Produces > 100-fold increase in histone acetylation and displays relatively low toxicity.

SCRIPTAID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


SCRIPTAID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 149)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29792 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471;
sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
Hebei Fengjia New Material Co., Ltd
+86-0311-87836622 +86-18712993135
sales01@tairunfaz.com China 8051 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 39040 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
trendseenbio@gmail.com China 11680 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8615965530500
nickzhang@hangyubiotech.com China 9948 58

  • GCK 1026
  • 1H-Benz[de]isoquinoline-2(3H)-hexanamide, N-hydroxy-1,3-dioxo-
  • Scriptide
  • 6-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-hydroxyhexanaMide
  • Scriptaid, Scriptide
  • Scriptide N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide
  • Scriptaid (GCK1026)
  • 6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide
  • GCK 1026; SCRIPTIDE; GCK1026; GCK-1026
  • CS-1136
  • Scriptaid, HDAC inhibitor
  • Scriptaid, 10 mM in DMSO
  • N-?HYDROXY-?1,?3-?DIOXO-?1H-?BENZ[DE]ISOQUINOLINE-?2(3H)-?HEXANANMIDE
  • 287383-59-9
  • Inhibitor
  • Amines
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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