Etoposide phosphate
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- CAS-Nr.
- 117091-64-2
- Englisch Name:
- Etoposide phosphate
- Synonyma:
- ETOPOPHOS;Etopofos;BMY 40481;ETOPOSIDE PHOSPHATE;ETOPOSIDE PHOSPHONATE;Etoposide 4'-Phosphate;ETOPOSIDEPHOSPHATE,ETOPOPHOS;Etoposide Phosphate (200 mg);Etoposide phosphate（BMY-40481);Etoposide phosphate≥ 98% (HPLC)
- CBNumber:
- CB5671214
- Summenformel:
- C29H33O16P
- Molgewicht:
- 668.54
- MOL-Datei:
- 117091-64-2.mol
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Etoposide phosphate Eigenschaften
- Siedepunkt:
- 907.7±75.0 °C(Predicted)
- Dichte
- 1+-.0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 1.13±0.50(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- Wasserl?slichkeit
- Water: 125 mg/mL (186.97 mM)
- InChIKey
- LIQODXNTTZAGID-OCBXBXKTSA-N
- SMILES
- O=C1OC[C@]2([H])[C@@H](C3=CC4OCOC=4C=C3[C@@H](C3C=C(C(=C(C=3)OC)OP(O)(O)=O)OC)[C@]21[H])O[C@H]1[C@@H]([C@H]([C@]2([H])O[C@@H](OC[C@@]2([H])O1)C)O)O
Etoposide phosphate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White crystalline powder
Verwenden
As a bioequivalent prodrug of the DNA topoisomerase II inhibitor Etoposide (E933750), Etoposide phosphate can be used in the treatment of a wide variety of hematological malignancies and solid tumors.
Application
Etoposide phosphate is a water-soluble prodrug of etoposide. Etoposide has played a very significant role in the treatment of various malignancies like germ cell tumors, Kaposi's sarcoma associated with AIDS, Hodgkin's disease, Non-Hodgkin's lymphoma, mycosis fungoides, acute myeloblasticleukemia, neuroblastoma, Ewing's sarcoma, paediatric rhabdomyosarcoma, ovarian carcinoma, small cell lung cancers, non-small cell lung cancers, gastric cancer and hepatomain the past two decades
[1].
Trademarks
Etopophos (Bristol-Myers
Squibb).
Etoposide phosphate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Etoposide phosphate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 129)Lieferanten
117091-64-2()Verwandte Suche:
- ETOPOSIDE PHOSPHATE
- ETOPOSIDE PHOSPHONATE
- ETOPOSIDE PHOSPHONATE, ETOPOPHOS
- BMY-40481, Etoposide 4'-Dihydrogenphosphate
- Etoposide 4'-Phosphate
- (5R,5aR,8aR,9S)-5-[3,5-DiMethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
- [5R-[5α,5aβ,8aα,9β(R*)]]-5-[3,5-DiMethoxy-4-(phosphonooxy)phenyl]-9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
- BMY 40481
- Etopofos
- Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-b-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-, (5R,5aR,8aR,9S)-
- ETOPOSIDEPHOSPHATE,ETOPOPHOS
- Etoposide phosphate≥ 98% (HPLC)
- Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-, (5R,5aR,8aR,9S)-
- ETOPOPHOS
- Etoposide Phosphate (200 mg)
- Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-, (5R,5aR,8aR,9S)-
- Etoposide phosphate（BMY-40481)
- 117091-64-2
- C29H33O16P
- Antineoplastic
- Carbohydrates & Derivatives
- Drug Analogues
- Heterocycles
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- API
