Pyridazin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Pyridazine is a nitrogen-containing six-membered heterocyclic compound belonging to the azine class, being an isomer of pyrimidine and pyrazine. It exists as a clear yellowish-brown liquid, insoluble in petroleum ether but readily soluble in methanol, ethanol, and diethyl ether. It is miscible with water, benzene, and dimethylformamide. Pyridazine is a weak base capable of forming salts with picric acid, hydrochloric acid, and similar compounds. It exhibits limited reactivity towards aromatic nucleophilic and electrophilic substitution reactions and demonstrates stability towards potassium permanganate. Reduction with sodium or alcohols cleaves the chain, converting it into 1,4-diaminobutane.
Verwenden
Pyrrolo[1,2-b]pyridazine 1 is a N-bridgehead aromatic heterocycle containing two nitrogen atoms, is obtained by the condensation of pyridazine and pyrrole.
synthetische
Pyridazine is obtained by the condensation of butenedial and hydrazine.
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Allgemeine Beschreibung
Pyridazine is a mono-basic 1,2-diazine compound, which is commonly prepared by the reaction of 1,4-dicarbonyls with hydrazines. Pyridazine ring is found in many herbicides like credazine, pyridatol and many pharmaceutical drugs like cefozopran, olaparib, talazoparib, and cadralazine.
Sicherheitsprofil
Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx.
Pyridazin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
