(+)-Taddol
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- CAS-Nr.
- 93379-49-8
- Englisch Name:
- (+)-Taddol
- Synonyma:
- ((4S,5S);97.0%(LC);(+)-TADDOL;(S,S)-taddol;SEEBACH REAGENT;bis(diphenylmethanol);(4S,5S)-2,2-Dimethyl-α;(+)-4,5-Bis[hydroxy(diphenyL;meso-2,3-Diphenylsuccinonitrile>(+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TE
- CBNumber:
- CB6152969
- Summenformel:
- C31H30O4
- Molgewicht:
- 466.57
- MOL-Datei:
- 93379-49-8.mol
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(+)-Taddol Eigenschaften
- Schmelzpunkt:
- 193-196 °C(lit.)
- Siedepunkt:
- 633.2±50.0 °C(Predicted)
- alpha
- -62.6 º (c=1 in chloroform)
- Dichte
- 1.200±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 12.28±0.29(Predicted)
- Aggregatzustand
- powder to crystal
- Farbe
- White to Almost white
- Optische Rotation
- [α]19/D +67°, c = 1 in chloroform
- BRN
- 4724097
- InChIKey
- RNSJHECWLNVNFE-LOYHVIPDSA-N
- SMILES
- C(O)(C1C=CC=CC=1)(C1C=CC=CC=1)[C@H]1OC(C)(C)O[C@@H]1C(O)(C1C=CC=CC=1)C1C=CC=CC=1 |&1:14,20,r|
- CAS Datenbank
- 93379-49-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
20/21/22-36/37/38 |
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| S-S?tze: |
26-36 |
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| WGK Germany |
3 |
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| HS Code |
29329990 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
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P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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(+)-Taddol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
Ligand for enantioselective Lewis-acid mediated Diels-Alder, allyltitanation of aldehydes, and Michael-Mukaiyama additions promoted by chiral Ti-complexes.
synthetische
Preparative Methods of (4R,5R)-2,2-Dimethyl-4,5-bis(hydroxydiphenylmethyl)-1,3-dioxolane: chiral titanates are usually prepared by mixing dichlorodiisopropoxytitanium and a
chiral 1,4-diol in toluene. Other solvents such as ether and dichloromethane can also be employed. The
alcohol exchange reaction takes place immediately at rt. Wherever necessary, liberated isopropyl alcohol is removed by azeotropic removal with toluene. The chiral 1,4-diols are prepared from dimethyl (or diethyl)
tartrate by a two-step procedure comprising acetalization followed by the addition of an aryl Grignard
reagent.
(+)-Taddol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(+)-Taddol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 164)Lieferanten
93379-49-8()Verwandte Suche:
Dichlor(diphenyl)silan
Dimethylphthalat
1,5-Diphenylcarbonohydrazid
1,3-Diphenyl-2-thioharnstoff
3,4'-DIAMINODIPHENYLMETHANE
Chlordiphenylphosphin
Dimethoxydiphenylsilan
Dimethylsulfid
Dimethylfumarat
Dimethyl ether
2,2-Dimethyl-1,3-dioxolan-4-ylmethanol
Ethan
Dimethylsulfoxid
N,N-Dimethylformamid
1,3-Dioxolan
2,5-Dimethylhexan-2,5-diol
2,2,4-Trimethyl-1,3-dioxolan
[2-(1-Propoxyethoxy)ethyl]benzol
- (+)-4,5-BIS[HYDROXY(DIPHENYL)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE
- (4S,5S)-2,2-DIMETHYL-ALPHA,ALPHA,ALPHA',ALPHA'-TETRAPHENYLDIOXOLANE-4,5-DIMETHANOL
- (4S,5S)-4,5-BIS(DIPHENYLHYDROXYMETHYL)-2,2-DIMETHYL-DIOXOLANE
- (+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TETRAPHENYL-D-THREITOL
- (2S,3S)-(+)-1,1,4,4-TETRAPHENYL-2,3-(2-PROPYLIDENEDIOXY)-BUTANE-1,4-DIOL
- (2S,3S)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TETRAPHENYL-1,2,3,4-BUTANETETROL
- (2S,3S)-(+)-4,5-BIS(DIPHENYLHYDROXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
- (+)-TADDOL
- SEEBACH REAGENT
- 1,3-Dioxolane-4,5-dimethanol, 2,2-dimethyl-.alpha.,.alpha.,.alpha.,.alpha.-tetraphenyl-, (4S,5S)-
- (4s,5s)-2,2-dimethyl-α,α,α',α'-tetraphenyldioxolane-4,5-dimethanol
- (+)-Taddol
(2S,3S)-(-)-4,5-Bis(diphenylhydroxymethyl)-2,2-dimethyl-1,3-dioxolane
- (+)-TRANS-4,5-BIS-(DIPHENYL-HYDROXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
- (+)-TRANS-ALPHA,ALPHA'-(2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DIYL)BIS(DIPHENYLMETHANOL)
- (+)-trans-A,A-(2,2-dimethyl-1,3-dioxolane -4,5-D
- Bishydroxydiphenylmethyldimethyldioxolane
- 1,1,4,4-Tetraphenyl-2,3,0-isopropylidene-D-threitol
- (4S,5S)-2,2-Dimethyl-alpha,alpha,alpha',alpha'-tetraphenyldioxolane-4,5-dimethan
- (2,2-)Dimethy-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)
- (4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-
4,5-dimethanol
- ((4S,5S)
- -2,2-Dimethyl-1,3-dioxolane-4,5-diyl)
- bis(diphenylmethanol)
- (4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-
4,5-dimethanol,99%e.e.
- 1,1,4,4-Tetraphenyl-2,3-O-isopropylidene-L-threitol
- (4S,5S)-2,2-DIMETHYL-A,A,A'',A'',-TETRAPHENYLDIOXOLANE-4,5-DIMETHANOL
- (+)-trans-α,α'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenlmethanol)
- (2,2-dimethyl)-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol
- (4S,5S)-4,5-Bis(diphenylhydroxymethyl)-2,2-dimethyldioxolane, (+)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-D-threitol, (+)-trans-α,αμ-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)
- (4S)-α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4α,5β-dimethanol
- (4S,5S)-α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol
- 2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4α,5β-dimethanol
- α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4α,5β-bismethanol
- 2,2-Dimethyl-1,3-dioxolane-4,5-bis(α,α-diphenylmethanol)
- α,α'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(α-phenylbenzyl alcohol)
- α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol
- ((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)
- (+)-trans-alpha,alpha'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)
(2S,3S)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-1,2,3,4-butanetetrol
(+)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-D-threitol
- (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane,97%
- (4S,5S)-2,2-Dimethyl-α,α,α′,α′-tetraphenyldioxolane-4,5-dimethanol ,98%
- (4S,5S)-2,2-Dimethyl-α,α,α',α'-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol
- (4S,5S)-2,2-Dimethyl-α,α,α′,α′-tetraphenyldioxolane-4,5-dimethanol
- (-)-2,3-O-isopropylidene-1,1,4,4-tetra-phenyl-D-threitol
- 1,3-Dioxolane-4,5-dimethanol, 2,2-dimethyl-α4,α4,α5,α5-tetraphenyl-, (4S,5S)-
- (+)-4,5-Bis[hydroxy(diphenyL
- Gal[2346Ac]β(1-3)GlcNPhth[46Bzd]-β-MP>
- meso-2,3-Diphenylsuccinonitrile>
- Neu5Acα(2-6)Galβ(1-3)GlcNAc-β-pNP>
- Methyl2,3,4,6-Tetra-O-pivaloyl-D-mannopyranoside>
- Neu5GcAc[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MP>
- '-tetraphenyl-1,3-dioxolane-4,5-dimethanol, 98% (99% ee)
- (4S,5S)-2,2-Dimethyl-α
- 97.0%(LC)
- (4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanol, 98% (99% ee)
- (S,S)-taddol
- (+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TE
- [(4S,5S)-5-[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl]-diphenylmethanol
- (4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanol
