Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat
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- CAS-Nr.
- 74936-72-4
- Bezeichnung:
- Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat
- Englisch Name:
- 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid
- Synonyma:
- DHP-050;PRAN-001;278-034-2;Le Chi Chi;1,4-DHPCOOH;UNII:5DU0E310OI;Nicardipine USP RC A;Nifedipine Impurity 2;Le Chi mother nucleus;Lercanidipine nucleus
- CBNumber:
- CB62129651
- Summenformel:
- C16H16N2O6
- Molgewicht:
- 332.31
- MOL-Datei:
- 74936-72-4.mol
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Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Eigenschaften
- Schmelzpunkt:
- 200-202C
- Siedepunkt:
- 505.0±50.0 °C(Predicted)
- Dichte
- 1.345±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO (Sparingly), Methanol (Slightly, Heated)
- pka
- 1.66±0.70(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Pale Yellow to Light Yellow
- InChI
- InChI=1S/C16H16N2O6/c1-8-12(15(19)20)14(13(9(2)17-8)16(21)24-3)10-5-4-6-11(7-10)18(22)23/h4-7,14,17H,1-3H3,(H,19,20)
- InChIKey
- JPXPPUOCSLMCHK-UHFFFAOYSA-N
- SMILES
- C1(C)NC(C)=C(C(O)=O)C(C2=CC=CC([N+]([O-])=O)=C2)C=1C(OC)=O
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid(1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester) is a pharmaceutical intermediate ingredient used in the preparation of Barnidipine, Lercanidipine hydrochloride and nitrendipine analogues. These drugs are all calcium channel blockers and are used to treat various forms of hypertension.
Chemische Eigenschaften
Light-Yellow Solid
Verwenden
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester can be used in the prevention and therapy of atherosclerotic degradation of arterial walls.
Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 291)Lieferanten
74936-72-4(Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat)Verwandte Suche:
1-Benzylpiperidin-3-ol
1,4-Dihydro-2,6-dimethyl-4-(2-ni-trophenyl)-3,5-pyridindicarbon-s?ure-dimethylester
Dimethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat
Nimodipin
Methylhydrogen-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylat
Niludipin
2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylatmonohydrochlorid
2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridin-3,5-dicarboxylat
Nitrendipin
- 2,6-DIMETHYL-5-METHOXY CARBONYL-4-(3-NITRO-PHENYL)-1,4-DIHYDROPYRIDINE-3-CARBOXYLIC ACID
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
- Lercanidipine mainring
- rac-1,4-Dihydro-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic Acid
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl ester
- 2,6-DiMethyl-5-Methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydorpyridine-3-carboxylic acid
- Methyl hydrogen 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
- 1,4-Dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5-pyr
- 1,4-DHPCOOH
- 1,4-DIHYDRO-5-METHOXYCARBONYL-2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3-CARBOXYLIC AC
- 2,6-DI-ME-4-(3-NITRO-PH)-1,4-2H-PYRIDINE-3,5-DICAR
- Nicardipine Carboxylic Acid Derivative
- Nifedipine Impurity 2
- Le Chi mother nucleus
- Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
- Nifedipine Impurity 2 (Nicardipine Carboxylic Acid Derivative )
- 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl ester
- Lercanidipine nucleus
- -1,4-dihydropyridine-3-carboxylic acid
- -2,6-dimethyl-4-(3-nitrophenyl)
- PHARMACEUTICAL RAW MATERIAL : 2,6-DIMETHYL-5-METHOXYCARBONYL-4-(3-NITROPHENYL)-1,4- DIHYDROPYRIDINE -3- CARBOXYLIC ACID
- 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydroxypyridine-3-carboxylic acid
- Nicardipine Carboxylic Acid Derivative (Nifedipine Impurity 2)
- Nimodipine Impurity 7
- Nicardipine USP RC A
- Lercanidipine Impurity 9
- Le Chi Chi
- 278-034-2
- 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
- Nicardipine USP Related Compound A
- PRAN-001
- Benidipine Impurity 18
- Le Cardipine Main Ring Reference
- 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitro phenyl)-1,4 dihydropyridine-3-carboxylic acid (74936-72-4)
- Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate >
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitro
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
- Benidipine Intermediate
- Nicardipine Related Compound A (Nicardipine Carboxylic Acid Impurity)
- 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)...
- Nicardipine Impurity88
- Nicardipine Carboxylic acid DerivativeQ: What is
Nicardipine Carboxylic acid Derivative Q: What is the CAS Number of
Nicardipine Carboxylic acid Derivative Q: What is the storage condition of
Nicardipine Carboxylic acid Derivative Q: What are the applications of
Nicardipine Carboxylic acid Derivative
- Lercanidipin Impurity 10
- 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylic acid monomethyl ester
- Methyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
- 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylicaci
- 2,6-Dimethyl-5-methoxy carbonyl-4-(3-nitrophenylo)-1,4-dihydropyridine-3-carboxylic acid
- Monomethyl 1, 4-dihydro-2, 6-dimethyl-4 -(3-nitrophenyl) pyridine-3, 5-dicarboxylic acid
- Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, ≥ 98.0%
- (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid
- Nicardipine EP Impurity 4
- Beninidipine hydrochloride impurity E
- UNII:5DU0E310OI
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylicacidmonomethylester
- DHP-050
- 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3-carboxylic acid
- Benzedine hydrochloride impuritiesE
- Methyl 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate
