5'-Guanylsure
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- CAS-Nr.
- 85-32-5
- Bezeichnung:
- 5'-Guanylsure
- Englisch Name:
- 5'-Guanylic acid
- Synonyma:
- GMP;5’-gmp;guanylate;GUANYLIC ACID;Guanidylic acid;[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate;G-5′-P;GMP·H2;Guo-5'-P;GMP FREE
- CBNumber:
- CB6271952
- Summenformel:
- C10H14N5O8P
- Molgewicht:
- 363.22
- MOL-Datei:
- 85-32-5.mol
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5'-Guanylsure Eigenschaften
- Schmelzpunkt:
- 220 - 223°C
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- L?slichkeit
- DMSO (Very Slightly, Heated, Sonicated), Water (Slightly, Sonicated)
- Aggregatzustand
- Solid
- Siedepunkt:
- 64 °C(Press: 0.05 Torr)
- Dichte
- 2.47±0.1 g/cm3(Predicted)
- pka
- 1.86±0.10(Predicted)
- Farbe
- White to Off-White
- Geruch (Odor)
- at 100.00%. odorless
- Kosmetik-Inhaltsstoffe Funktionen
- HUMECTANT
SKIN CONDITIONING
SKIN CONDITIONING - EMOLLIENT
- InChI
- 1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)
- InChIKey
- RQFCJASXJCIDSX-UHFFFAOYSA-N
- SMILES
- O=C(NC(N)=N1)C2=C1N(C=N2)C3C(O)C(C(COP(O)(O)=O)O3)O
- LogP
- -2.000
- CAS Datenbank
- 85-32-5(CAS DataBase Reference)
- EPA chemische Informationen
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| TSCA |
TSCA listed |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Toxizit?t |
LDLo intraperitoneal in mouse: 1500mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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5'-Guanylsure Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Biochemical research, flavor potentiator (disodium
salt).5-Guanylic Acid is a useful reagent for the chemo- and site-specific reductive amination of N2-guanine oligonucleotides.
Definition
The monophosphoric ester of guanine, i.e., the nucleotide containing guanine, d-ribose, and phosphoric acid. The phosphate may be esterified to either the 2, 3, or 5 carbon of ribose, yielding guanosine-2′-phosphate, guanosine-3′-phosphate, and guanosine-
Synthese
Under low-temperature conditions, guanosine reacts with a phosphorylating agent (e.g., phosphorus oxychloride POCl3) in an organic solvent (e.g., trimethyl phosphate) to generate the intermediate dichlorophosphate. Subsequently, this intermediate is hydrolyzed in the presence of water or ice to convert into a monophosphate, thereby yielding the target product, 5'-Guanylic acid.
l?uterung methode
Crystallise it from water and dry it at 110o. [Beilstein 26 III/IV 3910.]
5'-Guanylsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5'-Guanylsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 249)Lieferanten
85-32-5(5'-Guanylsure)Verwandte Suche:
- GUALOSINE 5'-PHOSPHATE (FEED ACID)
- GUANOSINE-5'-MONOPHOSPHATE (GMP) FREE ACID 98-100%
- GUANOSINE-5'-MONOPHOSPHORIC ACID, 97.0%
- [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid
- GUANILICACID
- GUANILLICACID
- Guanylic Aicd
- Guanosine-5''-monophosphoric acid (and/or unspecified salts)
- GUANOSINE 5''-MONOPHOSPHATE ACID
- Guanosine 2μ- & 3μ-monophosphate Mixed Isomers sodium salt
- Guo-5'-P
- guanosine-phosphate
- Guanosine 5'-monophosphate free acid
- Guanosine 5'-phosphate (GMP)
- G-5′-P
- Guanosine 5′-monophosphate from Saccharomyces cerevisiae
- GMP·H2
- 5’-guanylicacid
- guanidinemonophosphate
- guanosine5’-phosphate
- guanosinemonophosphate
- 5'-GUANOSINE MONOPHOSPHATE
- guanosine 5-(dihydrogen phosphate)
- guanosine 5-monophosphate free acid*sigma grade
- GMP FREE
- GUANOSINE 5'-MONOPHOSPHORIC ACID
- GUANOSINE 5'-MONOPHOSPHATE FREE ACID N-HYDRATE
- Guanosine 3ˊ(2ˊ)-monophosphate
- [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl phosphate
- Guanosine monophosphate, BR
- Guanine 5'-Monophosphate
- Guanosine acid
- 5'-GMP·H2
- 5'-Guanylic acid Solution in Acetonitrile/Water, 100μg/mL
- ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
- ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
- 5'-Guanylic acid USP/EP/BP
- TIANFUCHEM--85-32-5--5'-Guanylic acid
- Guanidylic acid
- Guanylic acid (5'-GMP)
- 5'-Guanylic acid
- Guanosine-5'-monophosphate
- guanosine-5'-triphosphate trisodium salt monohydrate
- C14057150 Guanosine-5`-monophosphate
- Apixaban Impurity 156
- (5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
- Guanosine-5＇-Monophosphate
- [(2R,3S,4R,5R)-5-(2-Amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
- 5’-gmp
- GMP
- guanylate
- GUANYLIC ACID
- 85-32-5
- 1644619-42-1
- C10H14N5O8P
- C10H14N5OPP
- Pharmaceutical Intermediates
