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ANTI-CASPASE-3

ANTI-CASPASE-3 Struktur
CAS-Nr.
Englisch Name:
ANTI-CASPASE-3
Synonyma:
ANTI-LICE;ANTI-YAMA;Anti-SCA1;ANTI-CASP3;ANTI-CPP32;ANTI-ICE-3;Anti-CPP32B;ANTI-APOPAIN;ANTI-CASPASE-3;ANTI-CPP32: HRPO
CBNumber:
CB6750242
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-CASPASE-3 Eigenschaften

storage temp. 
−20°C
Aggregatzustand
lyophilized powder
Biologische Quelle
rabbit
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Speicherklasse 12 - Non Combustible Liquids
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H312 Gesundheitssch?dlich bei Hautkontakt. Akute Toxizit?t dermal Kategorie 4 Warnung P280,P302+P352, P312, P322, P363,P501
H412 Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 3 P273, P501
Sicherheit
P273 Freisetzung in die Umwelt vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

ANTI-CASPASE-3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-Caspase 3, Active antibody has been used:
  • for western blotting of cytochrome c for caspase activation
  • as primary antibody in immunofluorescence staining of embryos and postnatal mice cryosections
  • in Western blot analysis of activated caspase 3
  • as a primary antibody in immunodetection of rat brain sections

Allgemeine Beschreibung

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3is an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases. CASP3is mapped to human chromosome 4q35.1.

Biochem/physiol Actions

Caspase 3 is one of the key effectors of apoptosis. It acts downstream of caspase 9 in the apoptotic pathway. During apoptosis, it gets activated by proteolytic cleavage into the 17-19 kDa (p17, p18) and 12 kDa (p12) active subunits. Any alteraion in CASP-3 in mice, causes premature lethality. It has also shown that the deletion of gene affects brain development resulting of hyperplasias and disorganized cell deployement. Clinically it is related to Huntington disease (HD). Caspase 3 brings about cell death by activating CAD (caspase activated DNAse I), an endonuclease that causes degradation of chromosomal DNA.

ANTI-CASPASE-3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-CASPASE-3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 48)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80
Shanghai Bohu Biotechnology Co., LTD 021-57763112 13585886131
3004987436@qq.com China 9692 58
Atlas antibodies --
order@atlasantibodies.com China 6586 58
Merck Millipore --
bioscience@merckgroup.com China 6839 58
Merck KGaA --
ordercn@merckgroup.com China 6394 58
Suzhou Situoyuan Trading Co., Ltd --
CHINA 40 58
Guangzhou Zhuanyan Biotechnology Co., Ltd. --
CHINA 6897 58
Beijing Laike Biotechnology Co., Ltd. --
CHINA 427 58
Guangzhou Keda Heng New Technology Co., Ltd. --
CHINA 6139 58
Hangzhou Zhiqi Biotechnology Co., Ltd. --
CHINA 1520 58

  • MONOCLONAL ANTIBODY TO CASPASE-3 (HUMAN) (31A1067)
  • Anti-Caspase 3 antibody produced in rabbit
  • Anti-Caspase 3, Active antibody produced in rabbit
  • Monoclonal Anti-Caspase 3 antibody produced in mouse
  • Anti-CASP3 antibody produced in rabbit
  • Monoclonal Anti-CASP3 antibody produced in mouse
  • CASPASE-3 (AB-2) MONOCLONAL ANTIBODY
  • CASPASE-3 (AB-3) MONOCLONAL ANTIBODY
  • CASPASE-3 (AB-4) MONOCLONAL ANTIBODY
  • ANTI-APOPAIN (AB-2), HUMAN
  • ANTI-APOPAIN (AB-2) MOUSE MAB
  • ANTI-APOPAIN (AB-3), HUMAN
  • ANTI-APOPAIN (AB-3) MOUSE MAB
  • ANTI-APOPAIN (AB-4) MOUSE MAB
  • ANTI-APOPAIN, ACTIVE RABBIT
  • ANTI-APOPAIN (HUMAN)
  • ANTI-APOPAIN, MOUSE
  • ANTI-APOPAIN
  • ANTI-APOPAIN (AB-1), HUMAN
  • ANTI-CASPASE-3 (AB-2)
  • ANTI-CASPASE-3 (AB-2), HUMAN
  • ANTI-CASPASE-3 (AB-2) MOUSE MAB
  • ANTI-CASPASE-3 (AB-3)
  • ANTI-CASPASE-3 (AB-3), HUMAN
  • ANTI-CASPASE-3 (AB-3) MOUSE MAB
  • ANTI-CASPASE-3 (AB-4), HUMAN
  • ANTI-CASPASE-3 (AB-4) MOUSE MAB
  • ANTI-CASP3
  • ANTI-CASP3 (AB-1), HUMAN
  • ANTI-CASP3 (AB-2), HUMAN
  • ANTI-CASP3 (AB-2) MOUSE MAB
  • ANTI-CASP3 (AB-3), HUMAN
  • ANTI-CASP3 (AB-3) MOUSE MAB
  • ANTI-CASP3 (AB-4) MOUSE MAB
  • ANTI-CASPASE-3 (HUMAN)
  • ANTI-CASPASE-3, HUMAN (RABBIT)
  • ANTI-CASPASE-3 RABBIT PAB
  • ANTI-CASPASE 3, ACTIVE RABBIT
  • ANTI-CPP32, MOUSE
  • ANTI-CPP32, ACTIVE RABBIT
  • ANTI-CPP32
  • ANTI-CPP32 (AB-1), HUMAN
  • ANTI-CPP32 (AB-2), HUMAN
  • ANTI-CPP32(AB-2) MOUSE MAB
  • ANTI-CPP32 (AB-3), HUMAN
  • ANTI-CPP32 (AB-3) MOUSE MAB
  • ANTI-CPP32 (AB-4) MOUSE MAB
  • ANTI-CPP32, ACTIVE FORM
  • ANTI-CASPASE 3 (CPP322)
  • ANTI-CASPASE 3 (CPP32, APOPAIN, YAMA)
  • ANTI-CASPASE-3(H-277)
  • ANTI-CASPASE-3, ACTIVE FORM
  • ANTI-CASPASE-3
  • ANTI-CASPASE-3 (AB-1), HUMAN
  • ANTI-CPP32: HRPO
  • ANTI-CPP32 (HUMAN)
  • ANTI-HUMAN CPP32
  • ANTI-HUMAN CASPASE-3
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