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10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin

Thioridazine Struktur
50-52-2
CAS-Nr.
50-52-2
Bezeichnung:
10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin
Englisch Name:
Thioridazine
Synonyma:
tp21;TP-21;Thioril;Meleril;Sonapax;Mallorol;Malloryl;Mellaril;Mellarit;Melleril
CBNumber:
CB6763367
Summenformel:
C21H26N2S2
Molgewicht:
370.57
MOL-Datei:
50-52-2.mol

10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin Eigenschaften

Schmelzpunkt:
72-74°
Siedepunkt:
bp0.02 230°
Dichte
1.1693 (rough estimate)
Brechungsindex
1.5800 (estimate)
Flammpunkt:
9℃
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
Practically insoluble in water, very soluble in methylene chloride, freely soluble in methanol, soluble in ethanol (96 per cent).
Aggregatzustand
liquid
pka
9.5(at 25℃)
Farbe
Colorless to off-white
Wasserl?slichkeit
1.113mg/L(22.5 ºC)
InChI
InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
InChIKey
KLBQZWRITKRQQV-UHFFFAOYSA-N
SMILES
C1=C2C(SC3=C(N2CCC2CCCCN2C)C=CC=C3)=CC=C1SC
NIST chemische Informationen
10H-Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylthio-(50-52-2)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher F,T
R-S?tze: 11-23/24/25-39/23/24/25-52/53
S-S?tze: 16-36/37-45-61
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
HS Code  2934302300
Giftige Stoffe Daten 50-52-2(Hazardous Substances Data)
Toxizit?t LD50 orally in rats: 995 ±39 mg/kg (Goldenthal)
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

An antipsychotic drug of the phenothiazine class. It is of particular interest because of its “atypical” properties, some of which may be due to its extensive bioconversion to active metabolites. The therapeutic and side effects of thioridazine and its metabolites involve blockade of brain dopamine receptors, but also actions mediated via blockage of muscarininc cholinergic and α-adrenergic receptors.

Chemische Eigenschaften

Colorless crystals. Soluble in water and alcohol.

Verwenden

In terms of antipsychotic activity, thioridazine is inferior to aminazine. It is most effective in mental and emotional disorders accompanied by fear, stress, and excitement. It is prescribed for various forms of schizophrenia, psychosis, and neurosis.

Definition

ChEBI: A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 80)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29792 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 20584 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15073 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739
info@dycnchem.com China 52705 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490
info@gihichemicals.com China 49967 58
Shanghai Likang New Materials Co., Limited
+86-16631818819 +86-17736933208
3684455296@qq.com China 9300 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 19956 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
+8618950047208
ellena@amitychem.com China 43414 58
Chongqing jooe co., ltd
+undefined86-15223382610
info@jooe.com China 15976 58

50-52-2(10-(2-(1-Methyl-2-piperidinyl)-ethyl)-2-(methylthio)-10H-pheno-thiazin)Verwandte Suche:


  • THIORIDAZINE
  • 10-[2-(1-Methyl-2-piperidyl)]-2-[methylthio] phenothiazine
  • THIORIDAZINE,1.0MG/MLINMETHANOL
  • 10-[2-(1-ethyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine
  • 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)- (9CI)
  • dl-Thioridazine
  • Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)- (6CI, 8CI)
  • Thioril
  • 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine
  • 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanyl-phenothiazine
  • THIORIDAZINE BASE
  • Thioridazine (200 mg)
  • 10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin
  • 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazin
  • 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin
  • 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine
  • 10-[2-(1-Methyl-2-piperdiyl)ethyl]-2-(methylthio)phenothiazine
  • 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine
  • 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-
  • 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine
  • 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylthio-10h-phenothiazine
  • Thioridazine solution
  • 10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine
  • 10-(2-(1-Methylpiperidin-2-yl)
  • 2-methylmercapto-10-(2-n-methyl-2-piperidyl)ethyl)phenothiazine
  • 3-methylmercapto-n-[2’-(n-methyl-2-piperidyl)ethyl]phenothiazine
  • Mallorol
  • Malloryl
  • Meleril
  • Mellaril
  • Mellaril-S
  • Mellarit
  • Mellerets
  • Mellerette
  • Melleretten
  • Melleril
  • melleril(liquid)
  • Phenothiazine, 10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)-
  • Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-
  • Sonapax
  • Thioridazin
  • Thioridazine, prolongatum
  • thioridazineprolongatum
  • tp21
  • TP-21
  • Thioridazine CRS
  • Thioridazine for system suitability CRS
  • Thioridazine USP/EP/BP
  • Thioridazine DISCONTINUED. Please see T368800.
  • Thioridazine (1662504)
  • hioridazine
  • Thioridazine Intermediate
  • 50-52-2
  • C21H26N2S2
  • Thioridazine
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