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Pramipexole dihydrochloride monohydrate

Pramipexole dihydrochloride monohydrate Struktur
191217-81-9
CAS-Nr.
191217-81-9
Englisch Name:
Pramipexole dihydrochloride monohydrate
Synonyma:
Pramipexole dihydrochloride monohydrate;Mirapex;Pramipexole for system suitability CRS;Pra-API;Pramipexole;Unii-3D867np06j;Pramipexole powder;PPX dihydrochloride;Pramipexole HCl hydrate;Pramipexole monohydrate
CBNumber:
CB6969615
Summenformel:
C10H20ClN3OS
Molgewicht:
265.8
MOL-Datei:
191217-81-9.mol

Pramipexole dihydrochloride monohydrate Eigenschaften

Schmelzpunkt:
290 °C(dec.)
storage temp. 
2-8°C
L?slichkeit
Freely soluble in water, soluble in methanol, sparingly soluble or slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
Aggregatzustand
Solid
Farbe
White to Almost white
Optische Rotation
Consistent with structure
Merck 
14,7705
BCS Class
1
Major Application
pharmaceutical (small molecule)
InChI
InChI=1/C10H17N3S.ClH.H2O/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;/h7,12H,2-6H2,1H3,(H2,11,13);1H;1H2/t7-;;/s3
InChIKey
ZTZQAWQFTIVKMU-DCFBZVEJNA-N
SMILES
NC1SC2C[C@@H](NCCC)CCC=2N=1.Cl.O |&1:5,r|
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
RTECS-Nr. DL3375000
HS Code  2934200000
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H336 Kann Schl?frigkeit und Benommenheit verursachen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Schl?frigkeit und Benommenheit) Warnung P261, P271, P304+P340, P312,P403+P233, P405, P501
Sicherheit
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

Pramipexole dihydrochloride monohydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Pramipexole dihydrochloride monohydrate is an activator of D2DR, D3DR and D4DR. Pramipexole has been found to have neuroprotective effects independent of its dopamine receptor agonism. It reduces mitochondrial reactive oxygen species (ROS) production and inhibits the activation of apoptotic pathways.

Chemische Eigenschaften

White or almost white, crystalline powder.

Verwenden

Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD) and a antidepressant. It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement)

Definition

ChEBI: A hydrate that is the monohydrate of the dihydrochloride salt of pramiprexole.

Allgemeine Beschreibung

Pramipexole Dihydrochloride is a non-ergot dopamine agonist widely used for the treatment of early and advanced Parkinson′s disease (PD). It is also used to treat restless legs syndrome.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Pramipexole dihydrochloride monohydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Pramipexole dihydrochloride monohydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 438)Lieferanten
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Henan Boweixin Biotechnology Co., Ltd.
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191217-81-9()Verwandte Suche:


  • (S)-2-Amino-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazol2HClH2Otetrahydrobenzothiazol
  • Mirapex,Sifrol,Mirapexin
  • (6S)-N'-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine hydrate dihydrochloride
  • (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride monohydrate
  • Pramipexole
  • 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, monohydrate, (6S)-
  • Pramipexole HCl hydrate
  • Unii-3D867np06j
  • PraMipexole dihydrochloride Monohy
  • Pramipexole Dihydrochloride Monohydrate (200 mg)
  • 2,6-BenzothiazolediaMine,4,5,6,7-tetrahydro-N6-propyl-,hydrochloride,hydrate(1:2:1),(6S)-
  • PraMipexole dihydrochloride Monohyrate
  • PraMipexole dihydrochloride hydrate
  • (6S)- 4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazolediamine,hydrochloride,hydrate (1:2:1)
  • PPX dihydrochloride
  • Pramipexole 2HCl Hydrate
  • Pramipexole (hydrochloride hydrate)
  • Pra-API
  • Pramipexole hydrochloride(Dihydrochloride monohydrate)
  • Pramipexole dihydrochloride monohydrate CRS
  • PramipexoleDihydrochlorideMonohydrate>
  • Pramipexole Dihydrochloride Monohyd
  • 99.9%, Pramipexole Dihydrochloride Monohydrate?
  • Pramipexole Dihydrochloride Monohydrate DISCONTINUED, offer P700755 or P700750
  • Pramipexole dihydrochloride 1-hydrate
  • (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole -2,6-diamine hydrate dihydrochloride
  • Pramipexole monohydrate
  • Pramipexole powder
  • Pramipexole for system suitability (Y0001187)
  • Pramipexole Dihydrochloride MonohydrateQ: What is Pramipexole Dihydrochloride Monohydrate Q: What is the CAS Number of Pramipexole Dihydrochloride Monohydrate Q: What is the storage condition of Pramipexole Dihydrochloride Monohydrate
  • Pramipexole Dihydrochloride Monohydrate (1553859)
  • Mirapex
  • Pramipexole dihydrochloride monohydrate
  • Pramipexole for system suitability CRS
  • Pramipexole hydrochloride monohydrate
  • (S)-N6-Propyl-4,5,6,7-tetrahydrobenzodthiazol-2,6-diamine dihydrochloride hydrate
  • Pramipexole dihydrochloride hydrate, 10 mM in DMSO
  • Pramipexole 2HCl monohydrate - Bio-X ?
  • Pramipexole dihydrochloride hydrate (Standard)
  • 191217-81-9
  • 91217-81-9
  • C10H17N3S2HClH2O
  • C10H17N3S2ClHH2O
  • Inhibitors
  • Pramipexole
  • 191217-81-9
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