2',5'-Dihydroxyacetophenon
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- CAS-Nr.
- 490-78-8
- Bezeichnung:
- 2',5'-Dihydroxyacetophenon
- Englisch Name:
- 2',5'-Dihydroxyacetophenone
- Synonyma:
- 2-ACETYLHYDROQUINONE;2,5-DIHYDROXYACETOPHENONE;1-(2,5-DIHYDROXYPHENYL)ETHAN-1-ONE;2,5-DHAP;Acetylhydroquinone;1-(2,5-DIHYDROXYPHENYL)ETHANONE;Ethanone, 1-(2,5-dihydroxyphenyl)-;2-hydroxy-1-(3-hydroxyphenyl)ethan-1-one;2,5-Dihydroxyphenyl methyl ketone, 2-Acetyl-1,4-dihydroxybenzene, 2-Acetylhydroquinone, Acetylquinol, Quinacetophenone;ACETYLQUINOL
- CBNumber:
- CB8221168
- Summenformel:
- C8H8O3
- Molgewicht:
- 152.15
- MOL-Datei:
- 490-78-8.mol
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2',5'-Dihydroxyacetophenon Eigenschaften
- Schmelzpunkt:
- 204-206 °C(lit.)
- Siedepunkt:
- 234.6°C (rough estimate)
- Dichte
- 1.2143 (rough estimate)
- Brechungsindex
- 1.4447 (estimate)
- storage temp.
- Store below +30°C.
- L?slichkeit
- dioxane: 50 mg/mL, clear
- pka
- 9.86±0.18(Predicted)
- Aggregatzustand
- Crystals or Crystalline Powder
- Farbe
- Yellow to yellow-green
- Wasserl?slichkeit
- insoluble
- BRN
- 637903
- Kosmetik-Inhaltsstoffe Funktionen
- SKIN CONDITIONING
BLEACHING
ANTIOXIDANT
- InChI
- 1S/C8H8O3/c1-5(9)7-4-6(10)2-3-8(7)11/h2-4,10-11H,1H3
- InChIKey
- WLDWSGZHNBANIO-UHFFFAOYSA-N
- SMILES
- CC(=O)c1cc(O)ccc1O
- LogP
- 1.274 (est)
- CAS Datenbank
- 490-78-8(CAS DataBase Reference)
- NIST chemische Informationen
- Ethanone, 1-(2,5-dihydroxyphenyl)-(490-78-8)
- EPA chemische Informationen
- Ethanone, 1-(2,5-dihydroxyphenyl)- (490-78-8)
2',5'-Dihydroxyacetophenon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
2',5'-Dihydroxyacetophenone is a natural phenolic compound that is found in many plants. It has been shown to have anti-inflammatory properties through its ability to inhibit the production of pro-inflammatory cytokines, such as tumor necrosis factor alpha and interleukin 1 beta.
Chemische Eigenschaften
yellow to yellow-green crystals or
Verwenden
2',5'-Dihydroxyacetophenone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.
Application
2',5'-Dihydroxyacetophenone inhibits the formation of reactive oxygen species and nitric oxide in rat neutrophils. It also has the ability to reduce oxidative stress by scavenging free radicals and inhibiting lipid peroxidation. The underlying mechanism for these effects is not fully understood but may be due to its ability to act as a substrate for matrix-assisted laser desorption ionization (MALDI). This means that it can react with protocatechuic acid molecules that are present in the sample preparation chamber, leading to polymerase chain reaction (PCR) amplification.
synthetische
Preparation by Fries rearrangement of hydroquinone diacetate,
with aluminium chloride(91%) (76%)(63–77%) (55–60%)
with zinc chloride in refluxing acetic acid (quantitative yield)
with boron trifluoride etherate in benzene at reflux (65%).
2',5'-Dihydroxyacetophenon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2',5'-Dihydroxyacetophenon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 398)Lieferanten
490-78-8(2',5'-Dihydroxyacetophenon)Verwandte Suche:
- 1-(2,5-dihydroxyphenyl)-ethanon
- 1-Acetyl-2,5-dihydroxybenzene
- 2,5-Dihydroxy-1-acetylbenzene
- 2’,5’-dihydroxy-acetophenon
- Acetophenone, 2',5'-dihydroxy-
- QUINACETOPHENONE
- 2-Acetylhydroquinone
Quinacetophenone
- 2',5'-DIHYDROXYACETOPHENONE FOR SYNTHESI
- 1-(2,5-Dihydroxyphenyl)ethan-1-one, 2-Acetylhydroquinone
- 2,5- twohydroxyAcetophenone
- WLN: QR CQ BV1
- ACETYLQUINOL
- 2,5-DIHYDROXYPHENYL METHYL KETONE
- 2-ACETYL-1,4-DIHYDROXYBENZENE
- 2',5'-Dihydroxyacetophenone 2-Acetylhydroquinone
- 2,5-Dihydroxyacetophenone, 98+%
- 2-Acethylhydroquinone
- 2,5-DIHYDROXYACETOPHENONE extrapure
- 2',5'-Dihydroxyacetophenone,97%
- 2',5'- Dihydroxyacetophnone
- 2′,5′-Dihydroxyacetophenone,2,5-Dihydroxyphenyl methyl ketone, 2-Acetyl-1,4-dihydroxybenzene, 2-Acetylhydroquinone, Acetylquinol, Quinacetophenone
- 2',5'-Dihydroxyaceto
- 2 ', 5'-hydroxyacetophenone
- 5'-Dihydroxyacetophenone
- 2',5'-Dihydroxyacetophenone>
- 2,5-Dihydroxy-Acetophenone (Quinacetophenone -98 %)
- 1-(2,5-DIHYDROXYPHENYL)ETHANONE
- Ethanone, 1-(2,5-dihydroxyphenyl)-
- 2-hydroxy-1-(3-hydroxyphenyl)ethan-1-one
- 2',5'- Di hyfeoxy acetophenone
- 2',5'-Dihydroxyacetophenone(Quinactophenone)
- 2',5'-Dihydroxyacetophenone, ≥ 98.0%
- 2',5'-Dihydroxyacetophenone
- 2,5-Dihydroxyacetophenone, 10 mM in DMSO
- 2',5'-Dihydroxyacetophenone, 95%
- 2′,5′-Dihydroxyacetophenone, CAS 490-78-8
- Norepinephrine Impurity 85
- 1-(2,5-DIHYDROXYPHENYL)ETHAN-1-ONE
- 2,5-Dihydroxyphenyl methyl ketone, 2-Acetyl-1,4-dihydroxybenzene, 2-Acetylhydroquinone, Acetylquinol, Quinacetophenone
- 2,5-DHAP
- 2,5-DIHYDROXYACETOPHENONE
- 2-ACETYLHYDROQUINONE
- Acetylhydroquinone
- 490-78-8
- 490-78-9
- HO2C6H3COCH3
- BioChemical
- Building Blocks
- C7 to C8
- Carbonyl Compounds
- Mass Spectrometry
- Matrices for MALDI Analysis
- Ketones
- Organic Building Blocks
- Protein Analysis
- Proteomics and Protein Expression
- KETONE
- Building Blocks
