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N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine

N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Struktur
931399-19-8
CAS-Nr.
931399-19-8
Englisch Name:
N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine
Synonyma:
GSK360A;N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine;N-[[1-(2-Cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]glycine;Glycine, N-[[1-(2-cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]-
CBNumber:
CB82620945
Summenformel:
C17H17FN2O5
Molgewicht:
348.3256832
MOL-Datei:
931399-19-8.mol

N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Eigenschaften

Schmelzpunkt:
194-198°C (dec.)
storage temp. 
2-8°C
L?slichkeit
Acetone (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
powder
Farbe
white to beige
InChI
1S/C17H17FN2O5/c18-10-3-4-12-11(7-10)15(23)14(16(24)19-8-13(21)22)17(25)20(12)6-5-9-1-2-9/h3-4,7,9,23H,1-2,5-6,8H2,(H,19,24)(H,21,22)
InChIKey
TYHRZQVUPPODPT-UHFFFAOYSA-N
SMILES
OC(C1=C(N2CCC3CC3)C=CC(F)=C1)=C(C(NCC(O)=O)=O)C2=O

Sicherheit

WGK Germany  WGK 3
Speicherklasse 11 - Combustible Solids

N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Beige Solid

Verwenden

GSK360A orally active HIF-PHD inhibitor. GSK360A exerts systemic and local effects by stabilizing HIF-1α signaling and improves long-term ventricular function, remodeling, and vascularity in a model of established ventricular dysfunction. These findings suggest that GSK360A may be suitable for the treatment of post-MI remodeling and heart failure.

N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 18)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 19956 58
J & K SCIENTIFIC LTD. 18210857532 18210857532
jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57422 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721
3525679403@qq.com China 4334 58
TargetMol Chemicals Inc. 4008200310 15002144251
marketing@tsbiochem.com China 24959 58
SHAANXI DIDEU MEDICHEM CO.LTD 029-029-81123119 17391733320
1021@dideu.com China 9394 58
Biosynth Biological Technology (Suzhou) Co Ltd --
sales@biosynth.com China 6051 58

  • GSK360A
  • N-[[1-(2-Cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]glycine
  • N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine
  • Glycine, N-[[1-(2-cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]-
  • 931399-19-8
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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