ChemicalBook >> CAS DataBase List >>N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine
N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine
![N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Structure](CAS/GIF/931399-19-8.gif)
- CAS No.
- 931399-19-8
- Chemical Name:
- N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine
- Synonyms
- GSK360A;N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine;N-[[1-(2-Cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]glycine;Glycine, N-[[1-(2-cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]-
- CBNumber:
- CB82620945
- Molecular Formula:
- C17H17FN2O5
- Molecular Weight:
- 348.3256832
- MDL Number:
- MFCD27977959
- MOL File:
- 931399-19-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-16 07:06:08
| Product description | Number | Pack Size | Price |
| GSK360A ≥98% (HPLC) | SML2175 | 5mg | $129 |
| GSK360A ≥98% (HPLC) | SML2175 | 25mg | $510 |
| GSK360A | 012982 | 5mg | $531 |
| GSK 360A | FG23706 | 1mg | $172.34 |
| GSK 360A | FG23706 | 5mg | $732.5 |
N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Properties
| Melting point | 194-198°C (dec.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | Acetone (Slightly, Heated), DMSO (Slightly), Methanol (Slightly) |
| form | powder |
| color | white to beige |
| InChI | 1S/C17H17FN2O5/c18-10-3-4-12-11(7-10)15(23)14(16(24)19-8-13(21)22)17(25)20(12)6-5-9-1-2-9/h3-4,7,9,23H,1-2,5-6,8H2,(H,19,24)(H,21,22) |
| InChIKey | TYHRZQVUPPODPT-UHFFFAOYSA-N |
| SMILES | OC(C1=C(N2CCC3CC3)C=CC(F)=C1)=C(C(NCC(O)=O)=O)C2=O |
| UNSPSC Code | 12352200 |
N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2175 | GSK360A ≥98% (HPLC) | 931399-19-8 | 5mg | $129 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML2175 | GSK360A ≥98% (HPLC) | 931399-19-8 | 25mg | $510 | 2026-04-30 | Buy |
| Usbiological | 012982 | GSK360A | 931399-19-8 | 5mg | $531 | 2026-06-03 | Buy |
| Biosynth | FG23706 | GSK 360A | 931399-19-8 | 1mg | $172.34 | 2026-06-04 | Buy |
| Biosynth | FG23706 | GSK 360A | 931399-19-8 | 5mg | $732.5 | 2026-06-04 | Buy |
N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Chemical Properties,Uses,Production
Chemical Properties
Beige Solid
Uses
GSK360A orally active HIF-PHD inhibitor. GSK360A exerts systemic and local effects by stabilizing HIF-1α signaling and improves long-term ventricular function, remodeling, and vascularity in a model of established ventricular dysfunction. These findings suggest that GSK360A may be suitable for the treatment of post-MI remodeling and heart failure.
in vivo
GSK360A (30 mg/kg i.g.) improves long-term ventricular function, remodeling, and vascularity in a model of established ventricular dysfunction[1].
| Animal Model: | male Lewis rats with ventricular dysfunction model[1] |
| Dosage: | 30 mg/kg |
| Administration: | oral gavage |
| Result: | Increased circulating levels of erythropoietin and hemoglobin and hemoxygenase-1 expression in the heart and skeletal muscle of male rats. |
N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Preparation Products And Raw materials
Raw materials
Preparation Products
N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine Suppliers
Global( 18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57422 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 4334 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24959 | 58 |
| SHAANXI DIDEU MEDICHEM CO.LTD | 029-029-81123119 17391733320 | 1021@dideu.com | China | 9393 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | -- | sales@biosynth.com | China | 6051 | 58 |
View Lastest Price from N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine manufacturers
GSK360A
N-[[1-(2-Cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]glycine
N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine
Glycine, N-[[1-(2-cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]-
931399-19-8
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