Sacubitril Impurity 7
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- CAS-Nr.
- 149709-44-4
- Englisch Name:
- Sacubitril Impurity 7
- Synonyma:
- LBQ657;Sacubitrilat;LCZ696-4;Deethyl Sakuba;LCZ-696 Impurity 1;SACUBITRIL DI ACID;Diacid of Sacubitril;LCZ696 impurities124;LBQ-657(Sacubitrilat);Sacubitrilat (LBQ-657)
- CBNumber:
- CB83133439
- Summenformel:
- C22H25NO5
- Molgewicht:
- 383.44
- MOL-Datei:
- 149709-44-4.mol
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Sacubitril Impurity 7 Eigenschaften
- Siedepunkt:
- 705.4±60.0 °C(Predicted)
- Dichte
- 1+-.0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM)
DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM)
- Aggregatzustand
- A crystalline solid
- pka
- 4.59±0.23(Predicted)
- Farbe
- White to off-white
- Optische Rotation
- [α]/D -35 to -27°, c =1 in methanol
- InChIKey
- DOBNVUFHFMVMDB-BEFAXECRSA-N
- SMILES
- OC(CCC(N[C@H](CC1=CC=C(C2=CC=CC=C2)C=C1)C[C@H](C(O)=O)C)=O)=O
Sacubitril Impurity 7 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
Sacubitril Impurity 7 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Sacubitril Impurity 7 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 141)Lieferanten
- (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid
- LCZ696-4
- Diacid of Sacubitril
- LCZ-696 Impurity 1
- Sacubitrilat (LBQ-657)
- Sacubitril Desethyl Impurity
- LCZ696 Impurity 900-04
- Deethyl Sakuba
- Sacubitril metabolite LBQ 657
- [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, (αR,γS)-
- 4-[[(1S,3R)-1-[([1,1'-Biphenyl]-4-yl)methyl]-3-methyl-4-hydroxy-4-oxobutyl]amino]-4-oxobutanoic acid
- (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)- 2-methylpentanoic aci
- Diacid of Sacubitril/ Sacubitril Desethyl Impurity/ Sacubitrilat
- LCZ696 impurities124
- Sacubitril metabolite LBQ 657Q: What is
Sacubitril metabolite LBQ 657 Q: What is the CAS Number of
Sacubitril metabolite LBQ 657 Q: What is the storage condition of
Sacubitril metabolite LBQ 657 Q: What are the applications of
Sacubitril metabolite LBQ 657
- quinoline,6-bromo-7-chloro-
- SACUBITRIL DI ACID
- Salcubatra calcium impurity J
- LBQ-657(Sacubitrilat)
- (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid
- Sacubitril metabolite LBQ 657-[d4]
- Sacubitril Impurity 4 (LBQ-657) (desethyl) (Sacubitrilat)
- Valsartan Impurity D-1
- Sacubitril Diacid Impurity
- LCZ696 impurity 900-04（LBQ657）
- Sacubitrilat, 10 mM in DMSO
- (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropylacylamino)-2-methylpentanoic acid
- Sacubitril Diacid impurity: (2R,4S)-4-(3-carboxypropanamido)-2-methyl-5-(4-phenylphenyl)pentanoic acid
- Desethyl Sacubitril (Sacubitrilat, LBQ657)
- Desethyl Sacubitril 5
- LBQ657
- Sacubitrilat
- Sacubitril valsartan impurity 1
- 149709-44-4
- 14709-44-4
