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4-Hydroxy-3-methoxybenzylalkohol

Vanillyl alcohol Struktur
498-00-0
CAS-Nr.
498-00-0
Bezeichnung:
4-Hydroxy-3-methoxybenzylalkohol
Englisch Name:
Vanillyl alcohol
Synonyma:
4-HYDROXY-3-METHOXYBENZYL ALCOHOL;Vanillin alcohol;FEMA 3737;vanillol;Vanillyl;Vanillinol;VANILLYL ALCOHOL(RG);4-HYDROXY-3-METHOXYBENZENEMETHANOL;4-Hydroxy-3-Methoxybenze-neMenthanol;4-HYDROXY-3-METHOXYBENZYL ALCOHOL (VANILLYL ALCOHOL)
CBNumber:
CB8709532
Summenformel:
C8H10O3
Molgewicht:
154.16
MOL-Datei:
498-00-0.mol

4-Hydroxy-3-methoxybenzylalkohol Eigenschaften

Schmelzpunkt:
110-117 °C (lit.)
Siedepunkt:
237.52°C (rough estimate)
Dichte
1.1690 (rough estimate)
Brechungsindex
1.4620 (estimate)
FEMA 
3737 | VANILLYL ALCOHOL
storage temp. 
Inert atmosphere,Room Temperature
L?slichkeit
soluble in Methanol
Aggregatzustand
Fine Crystalline Powder
pka
9.75±0.18(Predicted)
Farbe
Off-white to beige
Geruch (Odor)
at 100.00 %. sweet creamy vanilla caramellic coconut graham cracker tonka milky powdery
Geruchsart
creamy
Biologische Quelle
synthetic
Wasserl?slichkeit
Soluble in 95% ethanol (5 %), water, and oils.
JECFA Number
886
BRN 
1910044
Henry's Law Constant
9.6×104 mol/(m3Pa) at 25℃, McFall et al. (2020)
Stabilit?t:
Stable. Incompatible with strong oxidizing agents, strong acids.
InChI
1S/C8H10O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-4,9-10H,5H2,1H3
InChIKey
ZENOXNGFMSCLLL-UHFFFAOYSA-N
SMILES
COc1cc(CO)ccc1O
LogP
0.42
CAS Datenbank
498-00-0(CAS DataBase Reference)
NIST chemische Informationen
4-Hydroxy-3-methoxybenzyl alcohol(498-00-0)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36
WGK Germany  3
Hazard Note  Irritant
HS Code  29095090
Speicherklasse 11 - Combustible Solids
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

4-Hydroxy-3-methoxybenzylalkohol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

4-hydroxy-3-methoxybenzyl alcohol (also known as vanillyl alcohol) is often used as a deodorant component that is active in preventing the formation of body odor. It can also be used as a flavoring agent. Recent studies have also demonstrated that it has certain pharmacological effects. For example, it has been confirmed that it has certain neuro-protective effects through suppressing the oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells, making it a potential candidate for the treatment of neurodegenerative diseases such as Parkinson’s disease.

Chemische Eigenschaften

crystalline white to off-white powder

Verwenden

Used as a flavoring agent. Other possible uses, vanilla, coconut, cream and other dairy nuances, coumarin.

Allgemeine Beschreibung

Vanillyl alcohol belongs to the phenolic group of compounds which are widely used as oxidants in food products.

Synthese

Vanillyl alcohol is prepared from Vanillin by hydrogenation in presence of Platinum black.

Einzelnachweise

Brune, I, et al. "Under the influence of the active deodorant ingredient 4-hydroxy-3-methoxybenzyl alcohol, the skin bacterium Corynebacterium jeikeium moderately responds with differential gene expression." Journal of Biotechnology 127.1(2006):21-33.
Hsu, Lun Chung, Z. H. Wen, and K. Y. Lee. "Use of vanillyl alcohol for the treatment of Parkinson's disease." (2009).
Kim, I. S., D. K. Choi, and H. J. Jung. "Neuroprotective effects of vanillyl alcohol in Gastrodia elata Blume through suppression of oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells." Molecules 16.7(2011):5349.

4-Hydroxy-3-methoxybenzylalkohol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-Hydroxy-3-methoxybenzylalkohol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 437)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Beri Pharma Co., Ltd.
+8613417710166
sales@zhberi.com China 227 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81139210 17389186172
1077@dideu.com China 3801 58
Hebei Yanxi Chemical Co., Ltd.
+8618531123677
faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-86-13131129325 +8613131129325
sales1@chuanghaibio.com China 5224 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365
mina@chuanghaibio.com China 18126 58
Anhuyan (Hainan) Biotechnology Co., LTD
+8618163349544
mollylucking@foxmail.com China 3000 58
JINING XINHE CHEMICAL CO., LTD
+8615318402391
sales@xinhepharma.com China 809 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21585 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58

498-00-0(4-Hydroxy-3-methoxybenzylalkohol)Verwandte Suche:


  • 3,4-Dihydroxybenzyl alcohol 3-Methyl ester
  • α,4-Dihydroxy-3-Methoxytoluene
  • 4-Hydroxy-3-Methoxybenzyl alcohol, 99% 50GR
  • 3-Methoxy-4-hydroxybenzyl alcohol
  • Vanillic alcohol
  • 4-HYDROXY-3-METHOXYBENZYL ALCOHOL, 98+%
  • 4-Hydroxy-3-methoxybenzyl alcohol,99%
  • Hydroxy-3-Methoxybenzyl alc
  • 4-Hydroxy-3-Methoxybenzyl alcohol 98%
  • NSC 3993
  • 4-hydroxy-3-methoxy-benzenemethano
  • 4-hydroxy-3-methoxybenzyl
  • 4-hydroxy-3-methoxybenzylalcohol(vanillicalcohol)
  • Benzenemethanol, 4-hydroxy-3-methoxy-
  • RARECHEM AL BD 0101
  • VANILLYL ALCOHOL
  • VANILLYL ALCOHOL MI
  • VANILLYL ALCOHOL 98+%
  • Vanillyl alcohol (4-Hydroxy-3-methoxybenzyl alcohol)
  • A 4-DIHYDROXY-3-METHOXYTOLUENE
  • CITRONELLOL, D-(SG)
  • HOMOVANILLICALCOHOL
  • 4-HYDROXYMETHYL-2-METHOXY-PHENOL
  • Vanillin Impurity 3
  • 4-Hydroxy-3-methoxybenzyl alcohol USP/EP/BP
  • para-vanillyl alcohol
  • 4-Hydroxy-3-Methoxybenzyl Alcohol CAS 498-00-0 C8h10o3
  • TIANFU-CHEM 498-00-0 4-Hydroxy-3-methoxybenzyl alcohol
  • 4-Hydroxy-3-Methoxybenze-neMenthanol
  • Vanillinol
  • 4-HYDROXY-3-METHOXYBENZYL ALCOHOL (VANILLYL ALCOHOL)
  • VANILLYL ALCOHOL(RG)
  • Vanillyl alcohol (6CI, 8CI)
  • Vanillyl Alcohol, ≥ 98.0%
  • Vanillyl Alcohol (Vanillin)
  • Vanilly alcohol
  • Vanilla alcohol
  • 2-Hydroxy-5-(hydroxymethyl)anisole, 4-Hydroxy-3-methoxybenzyl alcohol, Vanillyl alcohol
  • 4-HYDROXY-3-METHOXYBENZENEMETHANOL
  • 4-HYDROXY-3-METHOXYBENZYL ALCOHOL
  • FEMA 3737
  • vanillol
  • Vanillyl
  • Vanillin alcohol
  • 498-00-0
  • 4980-00-0
  • 2560-07-7
  • HOC6H3CH2OHOCH3
  • HOC6H3OCH3CH2OH
  • CH3OC6H3OHCH2OH
  • ALCOHOL
  • Oxygen Compounds
  • Organic Building Blocks
  • Building Blocks
  • Alcohols
  • C7 to C8
  • Inhibitors
  • Bifunctional Linkers
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