NISOXETINE HYDROCHLORIDE
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- CAS-Nr.
- 57754-86-6
- Englisch Name:
- NISOXETINE HYDROCHLORIDE
- Synonyma:
- LY-94,939;Nsc298819;NisoxetineHCl;NISOXETINE HYDROCHLORIDE;Nisoxetine hydrochloride[N151];LY-94939; NSC298819; NISOXETINE HCL;4-((2-Nitrophenyl)thio)-2H-oxete hydrochloride;NISOXETINE HYDROCHLORIDE (LY-94,939) NOR PINEPHRINE UPTAKE;Nisoxetine hydrochloride, norepinephrine reuptake (NET) inhibitor;(±)-γ-(2-methoxyphenoxy)-n-methyl-benzenepropanamine hydrochloride
- CBNumber:
- CB9267088
- Summenformel:
- C17H22ClNO2
- Molgewicht:
- 307.82
- MOL-Datei:
- 57754-86-6.mol
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NISOXETINE HYDROCHLORIDE Eigenschaften
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- H2O: 20 mg/mL
- Aggregatzustand
- solid
- Farbe
- white
- Wasserl?slichkeit
- Soluble to 100 mM in water
- InChI
- InChI=1S/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H
- InChIKey
- LCEURBZEQJZUPV-UHFFFAOYSA-N
- SMILES
- C(CCNC)(OC1=CC=CC=C1OC)C1C=CC=CC=1.Cl
Sicherheit
| S-S?tze: |
22-26-36 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
NI2922170 |
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| Speicherklasse |
11 - Combustible Solids |
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NISOXETINE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
Nisoxetine Hydrochloride is a selective and potent inhibitor of norepinephrine transporter.
Biologische Aktivit?t
A potent and selective inhibitor of noradrenalin uptake with little or no affinity for a range of other neurotransmitter receptors.
Biochem/physiol Actions
Nisoxetineis a selective and potent noradrenaline reuptake inhibitor. It has a high affinity towards the noradrenaline transporter. Nisoxetine possesses antidepressant activity.
NISOXETINE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
NISOXETINE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 74)Lieferanten
57754-86-6()Verwandte Suche:
- LY-94,939
- (+/-)-GAMMA-(2-METHOXYPHENOXY)-N-METHYL-BENZENEPROPANAMINE HYDROCHLORIDE
- NISOXETINE HYDROCHLORIDE
- NISOXETINE HYDROCHLORIDE (LY-94,939) NOR PINEPHRINE UPTAKE
- (+/-)-g-(2-Methoxyphenoxy)-N-methylbenzenepropanaminehydrochloride
- NisoxetineHCl
- Nsc298819
- (±)-γ-(2-methoxyphenoxy)-n-methyl-benzenepropanamine hydrochloride
- LY-94,939, (±)-γ-(2-Methoxyphenoxy)-N-methyl-benzenepropanamine hydrochloride
- 4-((2-Nitrophenyl)thio)-2H-oxete hydrochloride
- LY-94939; NSC298819; NISOXETINE HCL
- 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine hydrochloride
- noradrenaline,channels,Monoamine Transporter,uptake,anesthetic,Inhibitor,Nisoxetine hydrochloride,Na channels,sodium,Nisoxetine,local,NET,antidepressant,Na+ channels,depression,Sodium Channel,transporter,inhibit
- Nisoxetine hydrochloride, norepinephrine reuptake (NET) inhibitor
- Nisoxetine hydrochloride[N151]
- 57754-86-6
- C17H21NO2HCl
- Potent and selective inhibitor of the norepinephrine transporter (Ki = 5.1 nM).
- Adrenoceptor
