N-Ethyltoluol-4-sulfonamid
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- CAS-Nr.
- 80-39-7
- Bezeichnung:
- N-Ethyltoluol-4-sulfonamid
- Englisch Name:
- N-Ethyl-p-toluenesulfonamide
- Synonyma:
- ETSM;N-E-PTSA;Unipex 108;Uniplex 108;Santicizer 3;Ncgc00091206-01;N-Tosylethylamine;N-Ethyl-p-toluenesul;Brinzolamide Impurity 1;Ethyl toluenesulfonamide
- CBNumber:
- CB9493133
- Summenformel:
- C9H13NO2S
- Molgewicht:
- 199.27
- MOL-Datei:
- 80-39-7.mol
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N-Ethyltoluol-4-sulfonamid Eigenschaften
- Schmelzpunkt:
- 63-65 °C(lit.)
- Siedepunkt:
- 208 °C745 mm Hg(lit.)
- Dichte
- 1.26 g/cm3
- Brechungsindex
- 1.5270 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 11.86±0.50(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents.
- Kosmetik-Inhaltsstoffe Funktionen
- FILM FORMING
PLASTICISER
- InChI
- InChI=1S/C9H13NO2S/c1-3-10-13(11,12)9-6-4-8(2)5-7-9/h4-7,10H,3H2,1-2H3
- InChIKey
- OHPZPBNDOVQJMH-UHFFFAOYSA-N
- SMILES
- C1(S(NCC)(=O)=O)=CC=C(C)C=C1
- LogP
- 1.960 (est)
- CAS Datenbank
- 80-39-7(CAS DataBase Reference)
- NIST chemische Informationen
- 4-Toluenesulfonamide, n-ethyl-(80-39-7)
- EPA chemische Informationen
- N-Ethyl-p-toluenesulfonamide (80-39-7)
N-Ethyltoluol-4-sulfonamid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Beschreibung
N-Ethyl-p-toluenesulfonamide (N-PTSA) is a white crystal commonly used as a pharmaceutical intermediate. It is synthesized by reacting ethyl acetoacetate with p-toluenesulfonyl chloride under alkaline conditions. In the pharmaceutical industry, N-PTSA is utilized in the synthesis of various drugs. The presence of ethyl and p-toluenesulfonamide groups in its structure makes N-PTSA valuable for specific applications in drug synthesis. Additionally, N-PTSA is employed as a plasticiser to enhance polymers more reactivity[1].
Chemische Eigenschaften
off-white crystalline solid
Verwenden
Plasticizer.
Allgemeine Beschreibung
Platelets (from dilute alcohol or ligroin) or off-white solid.
Air & Water Reaktionen
Insoluble in water.
Reaktivit?t anzeigen
An amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Brandgefahr
Flash point data for N-Ethyl-p-toluenesulfonamide are not available; however, N-Ethyl-p-toluenesulfonamide is probably combustible.
Einzelnachweise
[1] Xiao Bian . (2025). Solubility, solvent effects and thermodynamic properties of N-Ethyl-p-toluenesulfonamide in twelve pure organic solvents. Journal of the Taiwan Institute of Chemical Engineers, 170, Article 106009.
https://doi.org/10.1016/j.jtice.2025.106009
N-Ethyltoluol-4-sulfonamid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-Ethyltoluol-4-sulfonamid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 247)Lieferanten
80-39-7(N-Ethyltoluol-4-sulfonamid)Verwandte Suche:
- Benzenesulfonamide, N-ethyl-4-methyl-
- Ethyl toluenesulfonamide
- Ethylp-toluenesulfonamide
- n-ethyl-4-methyl-benzenesulfonamid
- n-ethyl-4-methylbenzenesulfonamide
- N-Ethyl-4-methyl-benzenesulfonamide
- N-Ethyltoluene-4-sulfonamide for synthesis
- n-ethyl-4-toluenesulfonamide
- N-Ethyl-p-methylbenzenesulfonamide
- N-Ethyl-p-tolylsulfonamide
- N-Tosylethylamine
- p-Tolueneethylsulfonamide
- p-Toluenesulfonamide, N-ethyl-
- p-Toluenesulfonyl-N-ethylamide
- Santicizer 3
- Unipex 108
- Uniplex 108
- ETSM
- p-Toluenesulfonylethylamide
- N-Ethyl Para Toluene Sulphonamide
- N-ETHYLTOLUENESULPHONAMIDE
- ETHYL-TOLUENESULPHONAMIDE
- N-ETHYL-4-METHYLBENZENESULPHONAMIDE
- N-ETHYL-4-TOLUENESULPHONAMIDE
- BENZENESULFONAMIDE,N-ETHYL-
- 4-Toluenesulfonic acid N-ethylamide
- N-E-PTSA
- N-ETHYL-TOLUENESULFONAMIDE
- N-ETHYL-P-TOLUENESULFONAMIDE
- N-Ethyltoluene-4-sulphonamide
- Ncgc00091206-01
- N-Ethyl-p-toluenesul
- N-Ethyl-p-toluenesulfonamide 98%
- N-Ethyl-p-toluenesulfonamide, >=99%
- N-Ethyl-p-toluenesulfonamide
- N-Ethyl-p-toluenesulfonaMide,N-Ethyltoluene-4-sulphonaMide
- Brinzolamide Impurity 1
- N-Ethyl-p-Toluene Sulfonamide, NEPTSA, N-Ethyl-p-toluenesulfonamide
- N-Ethyl-p-toluenesulfonamide>
- N-Ethyl-p-toluenesulfonamide ISO 9001：2015 REACH
- N-Ethyl-4-methylbenzenesulfonamide in Acetonitrile
- 3-Ethyl-4-methylbenzenesulfonamide
- N-Alkylp-toluenesulfonamide
- N-Ethyl-4-methylbenzenesulfonamide 100 μg/mL in Acetonitrile
- 80-39-7
- Protected Amines
- Organic Building Blocks
- Nitrogen Compounds
- Building Blocks
- Nitrogen Compounds
- Organic Building Blocks
- Protected Amines
