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ChemicalBook >> CAS DataBase List >>S-N(6)-methyladenosylhomocysteine

S-N(6)-methyladenosylhomocysteine

CAS No.
53228-06-1
Chemical Name:
S-N(6)-methyladenosylhomocysteine
Synonyms
S-N(6)-methyladenosylhomocysteine;Adenosine, 5'-S-[(3S)-3-amino-3-carboxypropyl]-N-methyl-5'-thio-
CBNumber:
CB01395897
Molecular Formula:
C15H22N6O5S
Molecular Weight:
398.44
MDL Number:
MOL File:
53228-06-1.mol
Last updated:2025-04-17 18:22:24

S-N(6)-methyladenosylhomocysteine Chemical Properties,Uses,Production

Uses

S-N6-Methyladenosylhomocysteine (Chart 1-1) is a potent inhibitor of histone methyltransferase DOT1L, with the IC50 of 0.29 μM. S-N6-Methyladenosylhomocysteine plays an important role in cancer research[1].

References

[1] Baylor College of Medicine. Selective inhibitors of histone methyltransferase DOT1L. United States, US20140100184 A1 2014-04-10.

S-N(6)-methyladenosylhomocysteine Preparation Products And Raw materials

Raw materials

Preparation Products

S-N(6)-methyladenosylhomocysteine Adenosine, 5'-S-[(3S)-3-amino-3-carboxypropyl]-N-methyl-5'-thio- 53228-06-1
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