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5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE structure

CAS No.: 875781-17-2

Chemical Name:: 5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE

Synonyms: 5-Bromo-1H-pyrazolo[3,4-b]pyridine;EOS-61661;4-b]pyridine;5-BROMO-1H-PYRAZO[3;5-broMo-1H-pyrazolo[3;5-bromo-7-azaindazole;7-Aza-5-bromo-1H-indole;5-Bromopyrazolo[3,4-b]pyridine;5-bromo-1H-pyrazoio[3,4-b]pyridine;5-Bromopyrazolo[3,4-b]pyridine >

CBNumber:: CB11092720

Molecular Formula:: C6H4BrN3

Molecular Weight:: 198.02

MDL Number:: MFCD05663982

MOL File:: 875781-17-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:04:45

Product description	Number	Pack Size	Price
5-Bromo-1H-pyrazolo[3,4-b]pyridine Aldrich	ADE000064	1g	$870
5-Bromopyrazolo[3,4-b]pyridine >95.0%(HPLC)(T)	B4363	1g	$114
5-Bromo-1H-pyrazolo[3,4-b]pyridine Asreported	261821	50g	$758
5-Bromo-1H-pyrazolo[3,4-b]pyridine Asreported	261821	100g	$1125
5-Bromo-1H-pyrazolo[3,4-b]pyridine Asreported	261821	250g	$1982
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5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE Properties

Melting point	198.0 to 202.0 °C
Boiling point	329.0±22.0 °C(Predicted)
Density	1.894±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	8.66±0.40(Predicted)
form	Solid
color	White to Yellow to Orange
InChI	InChI=1S/C6H4BrN3/c7-5-1-4-2-9-10-6(4)8-3-5/h1-3H,(H,8,9,10)
InChIKey	BASYLPMLKGQZOG-UHFFFAOYSA-N
SMILES	C12NN=CC1=CC(Br)=CN=2
CAS DataBase Reference	875781-17-2
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

Safety Statements

24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29333990

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE price More Price(93)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE000064	5-Bromo-1H-pyrazolo[3,4-b]pyridine Aldrich	875781-17-2	1g	$870	2026-04-30	Buy
TCI Chemical	B4363	5-Bromopyrazolo[3,4-b]pyridine >95.0%(HPLC)(T)	875781-17-2	1g	$114	2026-04-30	Buy
Usbiological	261821	5-Bromo-1H-pyrazolo[3,4-b]pyridine Asreported	875781-17-2	50g	$758	2026-06-03	Buy
Usbiological	261821	5-Bromo-1H-pyrazolo[3,4-b]pyridine Asreported	875781-17-2	100g	$1125	2026-06-03	Buy
Usbiological	261821	5-Bromo-1H-pyrazolo[3,4-b]pyridine Asreported	875781-17-2	250g	$1982	2026-06-03	Buy

Product number	Packaging	Price	Buy
ADE000064	1g	$870	Buy
B4363	1g	$114	Buy
261821	50g	$758	Buy
261821	100g	$1125	Buy
261821	250g	$1982	Buy

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE Chemical Properties,Uses,Production

Uses

5-Bromo-1H-pyrazolo[3,4-b]pyridine is a pyridine (P998910) derivative and useful building block, seen in its use in the synthetic preparation of 7-azaindazole chalcone derivatives as analgesics and anti-inflammatories.

Synthesis

5-Bromo-2-fluoropyridine-3-carboxaldehyde

875781-15-0

875781-17-2

The general procedure for the synthesis of 5-bromo-1H-pyrazolo[3,4-b]pyridine from 5-bromo-2-fluoro-3-formylpyridine was as follows: preparation of 5-bromo-1H-pyrazolo[3,4-b]pyridine (D-1-3). Compound D-1-2 (20 g, 0.1 mol) was mixed with an ethanol solution of anhydrous hydrazine (18 g, 0.56 mol) and heated to reflux overnight. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent was petroleum ether/ethyl acetate, 2:1, v/v) to confirm complete consumption of the raw material. Upon completion of the reaction, the reaction mixture was concentrated under vacuum to about 50 mL and subsequently poured into water (500 mL). The resulting mixture was filtered and the filter cake was washed sequentially with water (50mL x 3) and ether (20mL x 3). Finally, the filter cake was dried under vacuum to afford the target compound D-1-3 (9.0 g, 46% yield) as a yellow solid.

References

[1] Journal of Organic Chemistry, 2017, vol. 82, # 14, p. 7420 - 7427
[2] Patent: WO2009/16460, 2009, A2. Location in patent: Page/Page column 99-100
[3] Patent: WO2014/73904, 2014, A1. Location in patent: Paragraph 1496-1499
[4] Patent: CN103980272, 2016, B. Location in patent: Paragraph 0031; 0033
[5] Patent: WO2017/23987, 2017, A1. Location in patent: Paragraph 0610; 0612

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE synthesis

Synthesis of 5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE from 5-Bromo-2-fluoropyridine-3-carboxaldehyde

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE Preparation Products And Raw materials

Raw materials

5-Bromo-2-fluoropyridine-3-carboxaldehyde 1H-Pyrazol-5-amine HYDRAZINE Ethanol 5-Bromo-2-fluoropyridine

2-Bromomalonaldehyde 3-Aminopyrazole

1of2

Preparation Products

Methyl 1H-pyrazolo[3,4-b]pyridine-5-carboxylate Olverembatinib 1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID 5-bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine 6-BROMO-PYRAZOLO[1,5-A]PYRIMIDINE

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE Suppliers

Global( 295)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Wish Pharma Co., Ltd	+86-021-56789108 +8615021138722	Wishpharma0713@gmail.com	China	22	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16511	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	904	58
Accela ChemBio Inc.	+1-858-6993322 +86-18019713315	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Shenzhen Excellent Biotech Co., Ltd.	13480692018	ramyan@ex-biotech.com	CHINA	954	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29792	58

Supplier	Advantage
Shanghai Wish Pharma Co., Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Shanghai Arbor Chemical Co., Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Shenzhen Excellent Biotech Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58

View Lastest Price from 5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-02	5-Bromo-1H-pyrazolo[3,4-b]pyridine 875781-17-2	$1.10-9.90	1kg	99%min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-05-14	5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE 875781-17-2		1kg	Minimum 98%	300kg	Shanghai Wish Pharma Co., Ltd
2020-02-26	5-Bromo-1H-pyrazolo[3,4-b]pyridine 875781-17-2		100G	99.0%+	100 tons	Shaanxi Dideu Medichem Co. Ltd

5-Bromo-1H-pyrazolo[3,4-b]pyridine
875781-17-2
$1.10-9.90
99%min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE
875781-17-2
Minimum 98%
Shanghai Wish Pharma Co., Ltd

5-Bromo-1H-pyrazolo[3,4-b]pyridine
875781-17-2
99.0%+
Shaanxi Dideu Medichem Co. Ltd

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE Spectrum

5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE(875781-17-2)¹HNMR 5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE(875781-17-2)FT-IR

875781-17-2(5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE)Related Search:

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5-bromo-1H-pyrazoio[3,4-b]pyridine 5-Bromopyrazolo[3,4-b]pyridine 1H-Pyrazolo[3,4-b]pyridine, 5-broMo- 7-Aza-5-bromo-1H-indole 4-b]pyridine 5-broMo-1H-pyrazolo[3 5-Bromopyrazolo[3,4-b]pyridine EOS-61661 5-bromo-1H-pyrazole [3,4-B]pyridine 5-Bromopyrazolo[3,4-b]pyridine > 5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDINE 875781-17-2 5-Bromo-1H-pyrazolo[3,4-b]pyridine USP/EP/BP 5-BROMO-1H-PYRAZO[3 5-bromo-7-azaindazole 5-Bromo-1H-pyrazolo[3,4-b]pyridine 875781-17-2 875781-17-1 875781-78-2 Building Blocks Pyrazolo[x,x-y]pyridine CHIRAL CHEMICALS

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