ChemicalBook >> CAS DataBase List >>FTI-277
FTI-277
- CAS No.
- 170006-73-2
- Chemical Name:
- FTI-277
- Synonyms
- FTI-277;FTI-277;FTI277;METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA;N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester;N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester;N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
- CBNumber:
- CB1266050
- Molecular Formula:
- C22H29N3O3S2
- Molecular Weight:
- 447.61
- MDL Number:
- MFCD00952925
- MOL File:
- 170006-73-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 23:18:44
| Product description | Number | Pack Size | Price |
| FTI-277 trifluoroacetate salt ≥95% (HPLC), amorphous semi-solid | F9803 | 1mg | $209 |
| FTI-277 trifluoroacetate salt ≥95% (HPLC), amorphous semi-solid | F9803 | 5mg | $769 |
| FTI-277 trifluoroacetate salt | VGA00673 | 5mg | $1036.65 |
| FTI-277 trifluoroacetate salt | VGA00673 | 10mg | $1442.2 |
| FTI-277 trifluoroacetate salt | VGA00673 | 25mg | $2704.25 |
| Boiling point | 684.2±55.0 °C(Predicted) |
|---|---|
| Density | 1.222±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: soluble |
| pka | 9.81±0.10(Predicted) |
| form | amorphous semi-solid |
| Water Solubility | H2O: ≥2mg/mL |
| InChIKey | GJEFFRDWFVSCOJ-PXPMWPIZSA-N |
| SMILES | OC(=O)C(F)(F)F.COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c2ccccc2 |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
FTI-277 price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F9803 | FTI-277 trifluoroacetate salt ≥95% (HPLC), amorphous semi-solid | 170006-73-2 | 1mg | $209 | 2026-04-30 | Buy |
| Sigma-Aldrich | F9803 | FTI-277 trifluoroacetate salt ≥95% (HPLC), amorphous semi-solid | 170006-73-2 | 5mg | $769 | 2026-04-30 | Buy |
| Biosynth | VGA00673 | FTI-277 trifluoroacetate salt | 170006-73-2 | 5mg | $1036.65 | 2026-06-05 | Buy |
| Biosynth | VGA00673 | FTI-277 trifluoroacetate salt | 170006-73-2 | 10mg | $1442.2 | 2026-06-05 | Buy |
| Biosynth | VGA00673 | FTI-277 trifluoroacetate salt | 170006-73-2 | 25mg | $2704.25 | 2026-06-05 | Buy |
FTI-277 Chemical Properties,Uses,Production
Uses
Farnesyltransferase inhibitor 277 (FTI-277) has been used to:
- inhibit protein farnesylation in breast cell lines.
- in marrow-isolated adult multilineage inducible cells (MIAMI).
- inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).
Biochem/physiol Actions
Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.
FTI-277 Preparation Products And Raw materials
Raw materials
Preparation Products
FTI-277 Suppliers
Global( 64)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2922 | 55 | |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
View Lastest Price from FTI-277 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | FTI-277
170006-73-2
|
$1090.00-1970.00 | 99.63% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-01-10 | FTI-277 trifluoroacetate salt
170006-73-2
|
$1.00 | 1g | 99% | 200kg | Career Henan Chemical Co |
-
- FTI-277
170006-73-2
- $1090.00-1970.00
- 99.63%
- TargetMol Chemicals Inc.
-
- FTI-277 trifluoroacetate salt
170006-73-2
- $1.00
- 99%
- Career Henan Chemical Co
METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA
FTI-277
N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT
N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester
FTI-277;FTI277
L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester
170006-73-2
C22H29N3O3S2
C22H29N3O3S2C2HF3O2
