Tetrakis(hydroxymethyl)phosphonium chloride
- CAS No.
- 124-64-1
- Chemical Name:
- Tetrakis(hydroxymethyl)phosphonium chloride
- Synonyms
- THPC;SQJGLHL;THPS-UPC;meso-THPC;pyrosettkc;nci-c55061;AURORA KA-1157;HISHICOLIN THPC;tetramethylolphosphonium chloride;tetrakis(hydroxymethyl)phosphonium
- CBNumber:
- CB2166508
- Molecular Formula:
- C4H12ClO4P
- Molecular Weight:
- 190.56
- MDL Number:
- MFCD00031687
- MOL File:
- 124-64-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Tetrakis(hydroxymethyl)phosphonium chloride solution 80% in H2O | 404861 | 100ml | $82.9 |
| Tetrakis(hydroxymethyl)phosphonium chloride solution 80% in H2O | 404861 | 500ml | $241 |
| Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water) | T0607 | 25mL | $19 |
| Tetrakis(hydroxymethyl)phosphanium chloride | AAA12464 | 100g | $900 |
| Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H2O) 76-84%(Assaybytitration) | 37307 | 25ML | $25 |
| More product size | |||
| Melting point | 154°C |
|---|---|
| Boiling point | 115°C/760mmHg |
| Density | 1.341 g/mL at 25 °C |
| vapor pressure | 0Pa at 25℃ |
| refractive index |
n |
| form | Solution |
| pka | 6.05[at 20 ℃] |
| color | Clear light pink or yellow-green |
| Water Solubility | >=10 g/100 mL at 20 ºC |
| BRN | 3631669 |
| InChI | InChI=1S/C4H12O4P.ClH/c5-1-9(2-6,3-7)4-8;/h5-8H,1-4H2;1H/q+1;/p-1 |
| InChIKey | AKXUUJCMWZFYMV-UHFFFAOYSA-M |
| SMILES | [P+](CO)(CO)(CO)CO.[Cl-] |
| LogP | -9.8 |
| CAS DataBase Reference | 124-64-1(CAS DataBase Reference) |
| FDA UNII | 58WB2XCF8I |
| EPA Substance Registry System | Tetrakis(hydroxymethyl)phosphonium chloride (124-64-1) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H290-H301+H311-H314-H317-H360FD-H410 | |||||||||
| Precautionary statements | P201-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 21-25-38-41-42/43-51/53 | |||||||||
| Safety Statements | 22-26-36/37/39-45-60-61-23 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TA2450000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29319019 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 Met. Corr. 1 Repr. 1B Skin Corr. 1B Skin Sens. 1 |
|||||||||
| Hazardous Substances Data | 124-64-1(Hazardous Substances Data) | |||||||||
| Toxicity | mammal (species unspecified),LD50,oral,400mg/kg (400mg/kg),Kobunshi. High Polymers. Vol. 24, Pg. 788, 1975. | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Tetrakis(hydroxymethyl)phosphonium chloride price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 404861 | Tetrakis(hydroxymethyl)phosphonium chloride solution 80% in H2O | 124-64-1 | 100ml | $82.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 404861 | Tetrakis(hydroxymethyl)phosphonium chloride solution 80% in H2O | 124-64-1 | 500ml | $241 | 2026-04-30 | Buy |
| TCI Chemical | T0607 | Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water) | 124-64-1 | 25mL | $19 | 2021-12-16 | Buy |
| Biosynth | AAA12464 | Tetrakis(hydroxymethyl)phosphanium chloride | 124-64-1 | 100g | $900 | 2026-06-04 | Buy |
| Chem-Impex | 37307 | Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H2O) 76-84%(Assaybytitration) | 124-64-1 | 25ML | $25 | 2026-05-19 | Buy |
Tetrakis(hydroxymethyl)phosphonium chloride Chemical Properties,Uses,Production
Chemical Properties
Clear light pink or yellow-green solution
Uses
Flame-retarding agent for cotton fabrics. May be used in combination with triethylolamine and urea (Roxel process) or with triethanolamine and tris(1-aziridinyl) phosphine oxide.
Uses
Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H2O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl4.3H2O). It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications.
Definition
A crystalline compound made by the reaction of phosphine, formaldehyde, and hydrochloric acid.
General Description
Clear slightly viscous,colorless to yellow liquid (20% H2O solution).
Air & Water Reactions
Hygroscopic. Water soluble.
Reactivity Profile
Tetrakis(hydroxymethyl)phosphonium chloride reacts vigorously with oxidizers and alkalis. Reacts with cellulose.
Health Hazard
ACUTE/CHRONIC HAZARDS: Tetrakis(hydroxymethyl)phosphonium chloride may be corrosive. When heated to decomposition, it may emit very toxic fumes of POx, hydrogen chloride and bis(chloromethyl)ether. Decomposition of Tetrakis(hydroxymethyl)phosphonium chloride in an aqueous environment may produce phosphine, formaldehyde and hydrogen chloride.
Fire Hazard
Tetrakis(hydroxymethyl)phosphonium chloride is probably combustible.
Flammability and Explosibility
Non flammable
Purification Methods
Crystallise it from AcOH and dry it at 100o in a vacuum. An 80% w/v aqueous solution has d4 1.33 [Reeves J Am Chem Soc 77 3923 1955]. [Beilstein 1 IV 3062.]
Tetrakis(hydroxymethyl)phosphonium chloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Chongqing Chuandong Chemical (Group) Co. Ltd. | +86-13637972665 | wxc@cd1958.com | China | 81 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 17389186172 | 1077@dideu.com | China | 3796 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
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View Lastest Price from Tetrakis(hydroxymethyl)phosphonium chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-26 | Tetrakis(hydroxymethyl)phosphonium chloride
124-64-1
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-05-28 | Tetrakis (hydroxymethyl) Phosphonium Chloride
124-64-1
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-12-12 | Tetrakis(hydroxymethyl)phosphonium chloride
124-64-1
|
$1.00-4.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- Tetrakis(hydroxymethyl)phosphonium chloride
124-64-1
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Tetrakis (hydroxymethyl) Phosphonium Chloride
124-64-1
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Tetrakis(hydroxymethyl)phosphonium chloride
124-64-1
- $1.00-4.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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