2-Chloro-6-(trifluoromethyl)pyridine
- CAS No.
- 39890-95-4
- Chemical Name:
- 2-Chloro-6-(trifluoromethyl)pyridine
- Synonyms
- FINE ORGANIC COMPOUND;oro-6-(trifL;PYRIDINE DERIVAT;BUTTPARK 27\08-82;Chloro-6-(trifluoroMethyl)pyr;2-Chloro-5-trifluoromethylpyri;2-CHLORO-6-TRIFLUOROMETHYLPRIDINE;6-Chloro-2-(trifluoromethyl)pyridine;2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE;PYRIDINE, 2-CHLORO-6-(TRIFLUOROMETHYL)-
- CBNumber:
- CB2241526
- Molecular Formula:
- C6H3ClF3N
- Molecular Weight:
- 181.54
- MDL Number:
- MFCD00042226
- MOL File:
- 39890-95-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-6-(trifluoromethyl)pyridine 96% | 684724 | 1g | $25 |
| 2-Chloro-6-(trifluoromethyl)pyridine >98.0%(GC) | C1986 | 1g | $32 |
| 2-Chloro-6-(trifluoromethyl)pyridine >98.0%(GC) | C1986 | 5g | $95 |
| 2-Chloro-6-trifluoromethyl pyridine Asreported | 267394 | 25g | $345 |
| 2-Chloro-6-trifluoromethyl pyridine Asreported | 267394 | 50g | $460 |
| More product size | |||
| Melting point | 33 °C |
|---|---|
| Boiling point | 60-62°C 8mm |
| Density | 1.416±0.06 g/cm3(Predicted) |
| Flash point | 78°C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| Water Solubility | Insoluble in water |
| form | powder to lump |
| pka | -4.30±0.10(Predicted) |
| color | White to Almost white |
| FreezingPoint | 32.0 to 34.0 ℃ |
| BRN | 4308910 |
| InChI | InChI=1S/C6H3ClF3N/c7-5-3-1-2-4(11-5)6(8,9)10/h1-3H |
| InChIKey | ADVQMCQMDHBTHJ-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC(C(F)(F)F)=CC=C1 |
| CAS DataBase Reference | 39890-95-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P310-P305+P351+P338-P337+P313 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T;Xn,Xi,Xn,T | |||||||||
| Risk Statements | 25-20/21/22-36/37/38-36 | |||||||||
| Safety Statements | 26-36/37/39-45-36/37-9-36 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 2 Oral Eye Irrit. 2 |
|||||||||
| NFPA 704 |
|
2-Chloro-6-(trifluoromethyl)pyridine price More Price(84)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 684724 | 2-Chloro-6-(trifluoromethyl)pyridine 96% | 39890-95-4 | 1g | $25 | 2023-06-20 | Buy |
| TCI Chemical | C1986 | 2-Chloro-6-(trifluoromethyl)pyridine >98.0%(GC) | 39890-95-4 | 1g | $32 | 2026-04-30 | Buy |
| TCI Chemical | C1986 | 2-Chloro-6-(trifluoromethyl)pyridine >98.0%(GC) | 39890-95-4 | 5g | $95 | 2026-04-30 | Buy |
| Usbiological | 267394 | 2-Chloro-6-trifluoromethyl pyridine Asreported | 39890-95-4 | 25g | $345 | 2026-06-03 | Buy |
| Usbiological | 267394 | 2-Chloro-6-trifluoromethyl pyridine Asreported | 39890-95-4 | 50g | $460 | 2026-06-03 | Buy |
2-Chloro-6-(trifluoromethyl)pyridine Chemical Properties,Uses,Production
Chemical Properties
Colorless to off-white liquid (or White to off-white crystal)
Uses
2-Chloro-6-(trifluoromethyl)pyridine can be used in the synthesis of medicine, pesticide or biocidal product.
Chemical Reactivity
2-Chloro-6-(trifluoromethyl)pyridine is stable under recommended storage conditions, it reacts with strong oxidizing agents, strong acids, strong bases.
Synthesis
1929-82-4
39890-95-4
General procedure for the synthesis of 2-chloro-6-trichloromethylpyridine from 2-chloro-6-trichloromethylpyridine: 2-chloro-6-trichloromethylpyridine (700 g, 3.03 mol, feed rate 1.24 g/min) and anhydrous hydrogen fluoride (936 g, 46.8 mol, feed rate 1.66 g/min) were added successively to a tubular reactor fitted with a preactivated chromium oxide-alumina catalyst (210 g) in a tubular reactor at a reaction temperature of 330 °C. The reaction products were cooled with ice water and collected. The reaction products were collected after cooling with ice water and extracted with dichloromethane. The extract was washed with 10% potassium hydroxide solution, and the organic layer was separated and concentrated to give 490.0 g of crude 2-chloro-6-trifluoromethylpyridine, which was analyzed by GC for 95.03% purity and 89% reaction yield. The crude product was purified by fractionation to obtain 2-chloro-6-trifluoromethylpyridine with 98.0% purity and 80.0% yield.
References
[1] Patent: WO2016/178248, 2016, A1. Location in patent: Page/Page column 5
2-Chloro-6-(trifluoromethyl)pyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Jihui Chemical Co., Ltd. | +86-15053042019 | sales@jihuichem.com | China | 34 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +86-17331189928 | admin@guyunchem.com | China | 615 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Dalian Richfortune Chemicals Co., Ltd | +86-86-411-84820922 +86-8613904096939 | sales@richfortunechem.com | China | 305 | 57 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2988 | 55 |
View Lastest Price from 2-Chloro-6-(trifluoromethyl)pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2026-02-28 | 2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
|
250KG | Purity: 99% | 1000tons | Shandong Jihui Chemical Co., Ltd. | ||
 |
2025-11-18 | 2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited |
-
- 2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
- Purity: 99%
- Shandong Jihui Chemical Co., Ltd.
-
- 2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
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