Oxazolo[4,5-b]pyridine
![Oxazolo[4,5-b]pyridine Structure](CAS/GIF/273-97-2.gif)
- CAS No.
- 273-97-2
- Chemical Name:
- Oxazolo[4,5-b]pyridine
- Synonyms
- Oxazolo[4,5-b]pyridine
- CBNumber:
- CB22597434
- Molecular Formula:
- C6H4N2O
- Molecular Weight:
- 120.11
- MDL Number:
- MFCD13175183
- MOL File:
- 273-97-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Oxazolo[4,5-b]pyridine 97% | X42083 | 250mg | $24 |
| Oxazolo[4,5-b]pyridine 97% | X42083 | 1g | $40 |
| Oxazolo[4,5-b]pyridine 97% | X42083 | 5g | $170 |
| Oxazolo[4,5-b]pyridine 97% | X42083 | 10g | $530 |
| Oxazolo[4,5-b]pyridine 97% | AA003TFX | 250mg | $12 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P301+P312-P362+P364 |
| HS Code | 2934999090 |
Oxazolo[4,5-b]pyridine price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | X42083 | Oxazolo[4,5-b]pyridine 97% | 273-97-2 | 250mg | $24 | 2026-05-06 | Buy |
| Synthonix | X42083 | Oxazolo[4,5-b]pyridine 97% | 273-97-2 | 1g | $40 | 2026-05-06 | Buy |
| Synthonix | X42083 | Oxazolo[4,5-b]pyridine 97% | 273-97-2 | 5g | $170 | 2026-05-06 | Buy |
| Synthonix | X42083 | Oxazolo[4,5-b]pyridine 97% | 273-97-2 | 10g | $530 | 2026-05-06 | Buy |
| aablocks | AA003TFX | Oxazolo[4,5-b]pyridine 97% | 273-97-2 | 250mg | $12 | 2026-05-28 | Buy |
Oxazolo[4,5-b]pyridine Chemical Properties,Uses,Production
Definition
ChEBI: Oxazolo[4,5-b]pyridine is a mancude organic heterobicyclic parent and an oxazolopyridine.
Synthesis
16867-03-1
122-51-0
![Oxazolo[4,5-b]pyridine](/CAS/GIF/273-97-2.gif)
273-97-2
General procedure for the synthesis of oxazolo[4,5-b]pyridines from 2-amino-3-hydroxypyridine (90.1 mmol) and triethyl orthoformate (720.7 mmol): 2-amino-3-hydroxypyridine was dissolved in triethyl orthoformate under nitrogen protection, and p-toluenesulfonic acid (4.50 mmol) was added as catalyst. The reaction mixture was stirred at 160 °C overnight. Upon completion of the reaction, the excess of triethyl orthoformate was removed by distillation under reduced pressure. The crude product was purified by column chromatography with the eluent cyclohexane/ethyl acetate (5%-40% gradient elution) to afford oxazolo[4,5-b]pyridine as a beige solid in 68% yield. The product was detected by mass spectrometry (LRMS) with [M + H]+ m/z of 121.1; 1H NMR (DMSO-d6, 400 MHz) δ 9.04 (s, 1H), 8.58 (dd, J = 4.8, 1.4 Hz, 1H), 8.26 (dd, J = 8.2, 1.4 Hz, 1H), 7.50 (dd, J = 8.2, 4.8 Hz , 1H), 6.41 (s, 2H); 13C NMR (DMSO-d6, 101 MHz) δ 157.7, 154.5, 147.1, 142.0, 121.5, 120.1.
References
[1] Monatshefte fur Chemie, 2011, vol. 142, # 1, p. 87 - 91
[2] Journal of Organic Chemistry, 2011, vol. 76, # 13, p. 5444 - 5449
[3] European Journal of Medicinal Chemistry, 2013, vol. 66, p. 450 - 465
[4] Tetrahedron Letters, 1990, vol. 31, # 8, p. 1155 - 1156
[5] Synthetic Communications, 1992, vol. 22, # 20, p. 2891 - 2901
Oxazolo[4,5-b]pyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44816 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11780 | 60 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3979 | 55 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3998 | 55 |
| Shanghai Keepontech Co.,Ltd | 021-54849683 13601642561 | sales@keepontech.com | China | 997 | 59 |
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