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ChemicalBook >> CAS DataBase List >>2-ethynylpyrazine

2-ethynylpyrazine

CAS No.
153800-11-4
Chemical Name:
2-ethynylpyrazine
Synonyms
2-ethynylpyrazine;Pyrazine, 2-ethynyl-;2-Ethynylpyrazine 98%;2-Ethynylpyrazine - [E14588];2-Ethynyl-1,4-diazine, (Pyrazin-2-yl)acetylene
CBNumber:
CB22616270
Molecular Formula:
C6H4N2
Molecular Weight:
104.11
MDL Number:
MFCD13189804
MOL File:
153800-11-4.mol
MSDS File:
SDS
Last updated:2026-05-28 00:27:36
Product description Number Pack Size Price
2-Ethynylpyrazine DGA80011 1g $318.6
2-Ethynylpyrazine DGA80011 10g $2360
2-Ethynylpyrazine 98% OR53022 250mg $66
2-Ethynylpyrazine 98% OR53022 1g $196
2-Ethynylpyrazine 98% OR53022 5g $709

2-ethynylpyrazine Properties

Boiling point 180.3±20.0 °C(Predicted)
Density 1.11±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka -0.40±0.10(Predicted)
form crystalline solid
color Light gold to faint brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P261-P271-P280
HS Code  2933399990

2-ethynylpyrazine price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth DGA80011 2-Ethynylpyrazine 153800-11-4 1g $318.6 2026-06-04 Buy
Biosynth DGA80011 2-Ethynylpyrazine 153800-11-4 10g $2360 2026-06-04 Buy
Apolloscientific OR53022 2-Ethynylpyrazine 98% 153800-11-4 250mg $66 2026-06-04 Buy
Apolloscientific OR53022 2-Ethynylpyrazine 98% 153800-11-4 1g $196 2026-06-04 Buy
Apolloscientific OR53022 2-Ethynylpyrazine 98% 153800-11-4 5g $709 2026-06-04 Buy
Product number Packaging Price Buy
DGA80011 1g $318.6 Buy
DGA80011 10g $2360 Buy
OR53022 250mg $66 Buy
OR53022 1g $196 Buy
OR53022 5g $709 Buy

2-ethynylpyrazine Chemical Properties,Uses,Production

Synthesis

2-[2-(trimethylsilyl)ethynyl]pyrazine

291763-66-1

2-ethynylpyrazine

153800-11-4

To a solution of compound (CAS:291763-66-1) (3.0 g, 17.02 mmol) in THF (10 mL) was slowly added 1 M TBAF (tetrabutylammonium fluoride) solution over 9 min. The progress of the reaction was monitored by TLC (Thin Layer Chromatography) to confirm the complete conversion of the feedstock to the target product 2-alkynylpyrazines. After completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography to give 2-alkynylpyrazines (1.0 g, yield: 56.5%). LC-MS (Liquid Chromatography-Mass Spectrometry) analysis showed: m/z 105 ([M+H]+).

References

[1] Patent: WO2017/117708, 2017, A1. Location in patent: Page/Page column 18; 19
[2] Patent: WO2017/93544, 2017, A1. Location in patent: Page/Page column 97; 98
[3] Carbohydrate Research, 2011, vol. 346, # 9, p. 1083 - 1092
[4] Journal of Medicinal Chemistry, 2013, vol. 56, # 7, p. 3033 - 3047
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 7, p. 3532 - 3548

291763-66-1
153800-11-4
Synthesis of 2-ethynylpyrazine from 2-[2-(trimethylsilyl)ethynyl]pyrazine

2-ethynylpyrazine Preparation Products And Raw materials

2-ethynylpyrazine Suppliers

Global( 57)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8828 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Changzhou AniKare Pharmatech Co., Ltd.
+86-0519-8359-8696 +8618018249389 sales@anikare.com China 9981 58
Sichuan Biosynce Pharmatech Co., Ltd.
+8619950309693 diane@biosynce.com China 4871 58
Suzhou ARTK Medchem Co., Ltd.
+8618118463618 sales1@artkmedchem.com China 39021 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16512 58
Shanghai Scibiotron Pharmaceutical Co., Ltd
+86-16621589600 contact@scibiotron.com China 5783 58
SHANGHAI YOUNG-CHEM CHEMICAL CO., LTD.
+8613817489192 hebe@ychemchemical.com China 2435 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76

View Lastest Price from 2-ethynylpyrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-ethynylpyrazine pictures 2020-01-13 2-ethynylpyrazine
153800-11-4
$5.00 1KG 98% 100KG Career Henan Chemical Co
2-ethynylpyrazine 2-Ethynyl-1,4-diazine, (Pyrazin-2-yl)acetylene Pyrazine, 2-ethynyl- 2-Ethynylpyrazine 98% 2-Ethynylpyrazine - [E14588] 153800-11-4
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