ChemicalBook >> CAS DataBase List >>DesfluoroMethyl Fluticasone Propionate Disulfide
DesfluoroMethyl Fluticasone Propionate Disulfide
- CAS No.
- 201812-64-8
- Chemical Name:
- DesfluoroMethyl Fluticasone Propionate Disulfide
- Synonyms
- Fluticasone Propionate EP Impurity H;Fluticasone EP Imp H;Propionate Impurity H;Fluticasone Impurity 9;Fluticasone Disulphane Impurity;fluticasone propionate impurity EP-ZH;Fluticasone Propionate Disulfide Dimer Impurity;DesfluoroMethyl Fluticasone Propionate Disulfide;Fluticasone Impurity 8(Fluticasone EP Impurity H);17,17′-(disulfanediyldicarbonyl)bis(6α,9-difluoro-11β hydroxy- 16α-methyl-3-oxoandrosta-1,4-dien-17α-yl)dipropanoate
- CBNumber:
- CB22695792
- Molecular Formula:
- C48H58F4O10S2
- Molecular Weight:
- 935.09
- MDL Number:
- MFCD21363598
- MOL File:
- 201812-64-8.mol
Last updated:2026-05-28 00:06:13
| Product description | Number | Pack Size | Price |
| Desfluoromethyl Fluticasone Propionate Disulfide >95%(HPLC) | TRC-D289890-25MG | 25mg | $3444 |
| Desfluoromethyl Fluticasone Propionate Disulfide >95%(HPLC) | TRC-D289890-2.5MG | 2.5mg | $386 |
| Desfluoromethyl Fluticasone Propionate Disulfide >95%(HPLC) | TRC-D289890-1MG | 1mg | $200 |
| Desfluoromethyl fluticasone propionate disulfide | FD91086 | 5mg | $150 |
| Desfluoromethyl fluticasone propionate disulfide | FD91086 | 2mg | $150 |
| More product size | |||
| Melting point | >200°C |
|---|---|
| Boiling point | 905.0±75.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), DMSO (Slightly) |
| pka | 12.20±0.70(Predicted) |
| form | Solid |
| color | Off-White to Light Yellow |
| FDA UNII | 718MRE2B9T |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H312-H317-H302-H332-H360-H334 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P261-P285-P304+P341-P342+P311-P501 |
DesfluoroMethyl Fluticasone Propionate Disulfide price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-D289890-25MG | Desfluoromethyl Fluticasone Propionate Disulfide >95%(HPLC) | 201812-64-8 | 25mg | $3444 | 2026-06-03 | Buy |
| TRC | TRC-D289890-2.5MG | Desfluoromethyl Fluticasone Propionate Disulfide >95%(HPLC) | 201812-64-8 | 2.5mg | $386 | 2026-06-03 | Buy |
| TRC | TRC-D289890-1MG | Desfluoromethyl Fluticasone Propionate Disulfide >95%(HPLC) | 201812-64-8 | 1mg | $200 | 2026-06-03 | Buy |
| Biosynth | FD91086 | Desfluoromethyl fluticasone propionate disulfide | 201812-64-8 | 5mg | $150 | 2026-06-04 | Buy |
| Biosynth | FD91086 | Desfluoromethyl fluticasone propionate disulfide | 201812-64-8 | 2mg | $150 | 2026-06-04 | Buy |
DesfluoroMethyl Fluticasone Propionate Disulfide Chemical Properties,Uses,Production
Uses
Desfluoromethyl Fluticasone Propionate Disulfide is the disulfide conjugated dimer of Fluticasone Propionate (F599500), a derivative of flumethasone and an anti-inflammatory agent.
Synthesis
This is an impurity formed during the synthesis of Fluticasone Propionate. Its formation involves key steps: oxidative cleavage of the C-17 hydroxymethyl group in flumetasone, activation of the resulting acid and reaction with HS to give a thiocarboxylic acid, esterification of the C-17 hydroxyl, and S-alkylation of the thiocarboxylic acid with bromochloromethane.
DesfluoroMethyl Fluticasone Propionate Disulfide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 83)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +86-18627948422 | sale@hdimpurity.com | China | 3681 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| CR Corporation Limited | fred.wen@crcorporation.cn | China | 8645 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25356 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43333 | 58 |
| Moxin Chemicals | +86-17320513646 +86-17320513646 | anna@molcoo.com | China | 10000 | 58 |
| Pure Research Chemicals | +86-13564847951 +86-18019592524 | info@purerechem.com | China | 1000 | 58 |
| Sinco Pharmachem (ShenZhen) R&D Co., Ltd. | +86-18603013401 | jack.lin@sincopharmachem.com | China | 10000 | 58 |
View Lastest Price from DesfluoroMethyl Fluticasone Propionate Disulfide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-12 | Fluticasone Propionate Impurity H
201812-64-8
|
10mg | 98% | 500mg | ShenZhen H&D Pharmaceutical Technology Co., LTD |
-
- Fluticasone Propionate Impurity H
201812-64-8
- 98%
- ShenZhen H&D Pharmaceutical Technology Co., LTD
201812-64-8(DesfluoroMethyl Fluticasone Propionate Disulfide)Related Search:
5-Chloromethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate
FLUTICASONE PROPIONATE INTERMEDIATE
Fluticasone IMpurity
Fluticasone
Fluticasone
5-Iodomethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate
FLUTICASONE FUROATE
Fluticasone propionate-d5
Fluticasone propionate
(6α,11β,16α,17α)-(6'α,11'β,16'α,17'α)-17,17'-(Trithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-androsta-1,4-dien-3-one
11-Oxo Fluticasone Propionate
(6α,11β,16α,17α)-6,9-difluoro-11,17-dihydroxy-16-Methyl-3-oxo-Androsta-1,4-diene-17-carboxylic Acid (6α,11β,16α,17α)-6,9-difluoro-17-[[(fluoroMethyl)thio]carbonyl]-11-hydroxy-16-Methyl-3-oxoandrosta-1,4-dien-17-yl Ester
FLUTICASONE PROPIONATE, 17-BETA CARBOXYLIC ACID
Fluticasone EP IMpurity B
Ticabesone Propionate
1of4
Androsta-1,4-dien-3-one, 17,17'- (dithiodicarbonyl)bis[6,9- difluoro-11-hydroxy-16-Methyl-17-(1-oxopropoxy)-, (6α,11β, 16α,17α)-(6'α,11'β,16'α,17'α)-
Fluticasone Propionate Disulfide Dimer Impurity
Fluticasone Disulphane Impurity
DesfluoroMethyl Fluticasone Propionate Disulfide
Fluticasone Impurity 9
Fluticasone Impurity 8(Fluticasone EP Impurity H)
Propionate Impurity H
Fluticasone Propionate EP Impurity H/Fluticasone Disulphane Impurity/Desfluoromethyl Fluticasone Propionate Disulfide/17,17′-(Disulphanediyldicarbonyl)bis(6α,9-difluoro-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-yl) dipropanoate
Fluticasone EP Imp H
17,17′-(disulfanediyldicarbonyl)bis(6α,9-difluoro-11β hydroxy- 16α-methyl-3-oxoandrosta-1,4-dien-17α-yl)dipropanoate
Fluticasone Propionate EP Impurity H
(6α,11β,16α,17α)-(6'α,11'β,16'α,17'α)-17,17'-(Dithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)androsta-1,4-dien-3-one
(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic dithioperoxyanhydride (Fluticasone Propionate Impurity)
fluticasone propionate impurity EP-ZH
(6alpha,11beta,16alpha,17alpha)-(6'alpha,11'beta,16'alpha,17'alpha)-17,17'-(Dithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxo-propoxy)androsta-1,4-dien-3-one
201812-64-8
C48H58F4O10S2
Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
