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FLUTICASONE PROPIONATE INTERMEDIATE

FLUTICASONE PROPIONATE INTERMEDIATE structure

CAS No.: 80474-45-9

Chemical Name:: FLUTICASONE PROPIONATE INTERMEDIATE

Synonyms: (6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-carbothioic acid;Fn-1;Fluticasone intermediate;(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carbothioic S-acid;FN-1(1);BNKY011-FP04;Fluticasone Impurity 3;oxopropoxy)-, (6α,11β,16α,17α)-;Fluticasone intermediate FN-1(1);FLUTICASONE PROPIONATE INTERMEDIATE

CBNumber:: CB8794680

Molecular Formula:: C24H30F2O5S

Molecular Weight:: 468.56

MDL Number:: MFCD09029044

MOL File:: 80474-45-9.mol

MSDS File:: SDS

Last updated:2026-05-28 05:55:03

Product description	Number	Pack Size	Price
FN1 Purifiedbyimmunoaffinitychromatography.	562848	50ug	$403
FN1 Purifiedbyimmunoaffinitychromatography.	562848	100ug	$531
6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1,4-diene-17β-carbothioic acid	FD21850	0.025g	$150
6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1,4-diene-17β-carbothioic acid	FD21850	0.05g	$178.48
6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1,4-diene-17β-carbothioic acid	FD21850	0.1g	$285.56
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FLUTICASONE PROPIONATE INTERMEDIATE Properties

Melting point	158-160C
Boiling point	563.3±50.0 °C(Predicted)
Density	1.31
vapor pressure	6Pa at 20℃
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	2.99±0.70(Predicted)
form	Solid
color	White to Off-White
Water Solubility	50mg/L at 20℃
Stability	Air Sensitive
LogP	2.64
FDA UNII	YXC5X4NLK5

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
REACH Registrations	Active

FLUTICASONE PROPIONATE INTERMEDIATE price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	562848	FN1 Purifiedbyimmunoaffinitychromatography.		50ug	$403	2026-06-03	Buy
Usbiological	562848	FN1 Purifiedbyimmunoaffinitychromatography.		100ug	$531	2026-06-03	Buy
Biosynth	FD21850	6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1,4-diene-17β-carbothioic acid	80474-45-9	0.025g	$150	2026-06-04	Buy
Biosynth	FD21850	6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1,4-diene-17β-carbothioic acid	80474-45-9	0.05g	$178.48	2026-06-04	Buy
Biosynth	FD21850	6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1,4-diene-17β-carbothioic acid	80474-45-9	0.1g	$285.56	2026-06-04	Buy

Product number	Packaging	Price	Buy
562848	50ug	$403	Buy
562848	100ug	$531	Buy
FD21850	0.025g	$150	Buy
FD21850	0.05g	$178.48	Buy
FD21850	0.1g	$285.56	Buy

FLUTICASONE PROPIONATE INTERMEDIATE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

An intermediate in the synthesis of Fluticasone Propionate.

Flammability and Explosibility

Not classified

FLUTICASONE PROPIONATE INTERMEDIATE synthesis

Synthesis of FLUTICASONE PROPIONATE INTERMEDIATE from (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid

FLUTICASONE PROPIONATE INTERMEDIATE Preparation Products And Raw materials

Raw materials

3-(3,4-Dimethoxyphenyl)-pentane-2-one THIOPROPIONIC ACID FLUTICASONE PROPIONATE, 17-BETA CARBOXYLIC ACID Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, (6a,11b,16a,17a)- (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid

Diethylamine Propionyl chloride

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Preparation Products

Fluticasone propionate

FLUTICASONE PROPIONATE INTERMEDIATE Suppliers

Global( 109)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8618627948422	sale@hdimpurity.com	China	3681	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16511	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
Lianyungang happen teng technology co., LTD	15950718863	wang666xt@163.com	CHINA	295	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
BIONNA MEDICINE CO.,LTD	01056380788-8515; +8618518759099	790226113@qq.com	China	52	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58

Supplier	Advantage
ShenZhen H&D Pharmaceutical Technology Co., LTD	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
Lianyungang happen teng technology co., LTD	58
career henan chemical co	58
Standardpharm Co. Ltd.	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
BIONNA MEDICINE CO.,LTD	58
SIMAGCHEM CORP	58

View Lastest Price from FLUTICASONE PROPIONATE INTERMEDIATE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-02	6α, 9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1, 4-diene-17β-carbothioic Acid 80474-45-9	$1.10-9.90	1kg	99%min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-03-12	Fluticasone Propionate Intermediate Impurity E 80474-45-9		10mg	98%	500mg	ShenZhen H&D Pharmaceutical Technology Co., LTD
2021-07-13	FLUTICASONE PROPIONATE INTERMEDIATE 80474-45-9	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

6α, 9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1, 4-diene-17β-carbothioic Acid
80474-45-9
$1.10-9.90
99%min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Fluticasone Propionate Intermediate Impurity E
80474-45-9
98%
ShenZhen H&D Pharmaceutical Technology Co., LTD

FLUTICASONE PROPIONATE INTERMEDIATE
80474-45-9
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

FLUTICASONE PROPIONATE INTERMEDIATE Spectrum

FLUTICASONE PROPIONATE INTERMEDIATE(80474-45-9)¹HNMR

80474-45-9(FLUTICASONE PROPIONATE INTERMEDIATE)Related Search:

Fluticasone propionate Fluticasone (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol 6α,9α-difluoro-17α-(furan-2-yl)carbonyloxy-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic acid FLUTICASONE PROPIONATE, 17-BETA CARBOXYLIC ACID

Fluticasone IMpurity Fluticasone Fluticasone EP IMpurity B 5-Iodomethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate FLUTICASONE FUROATE

Ticabesone Propionate Fluticasone Acetate (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid DesfluoroMethyl Fluticasone Propionate Disulfide (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)-

Fluticasone propionate-d5 5-Chloromethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate (6α,11β,16α,17α)-(6'α,11'β,16'α,17'α)-17,17'-(Trithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-androsta-1,4-dien-3-one

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Androsta-1,4-diene-17- carbothioic acid, 6,9-difluoro -11-hydroxy-16-Methyl-3-oxo-17-(1-oxopropoxy)-, (6α,11β, 16α,17α)- Fluticasone intermediate FN-1(1) FLUTICASONE PROPIONATE INTERMEDIATE 6,9-DIFLUORO-11B-HYRDOXY-16-METHYL-3-OXO-17-PROPIONYLOXYANDROSTA-1,4-DIENE-17B-CARBPTHIOCACID (6alpha,11beta,,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxo-propoxy)androsta-1,4-diene-17-carbothioic acid 6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)-androsta-1,4-diene-17β-carbothioic Acid 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1- Androsta-1,4-diene-17-carbothioic acid oxopropoxy)-, (6α,11β,16α,17α)- 6a,9a-difluoro-l1~-hydroxy-l6a-methyl- 17a-propionyloxy-3-oxoandrosta-l,4-diene-l7~-carbothioic acid (6α,11β,,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxo-propoxy)androsta-1,4-diene-17-carbothioic acid Fluticasone Carbothioic Acid Impurity BNKY011-FP04 FN-1(1) Fluticasone Impurity 3 Fluticasone Carbothioic Acid Propionate Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, (6α,11β,16α,17α)- Recombinant Human NovoNectin Protein, No Tag FLUTICASONE INTERMEDIATE/FLUTICASONE PROPIONATE INTERMEDIATE CAS NO:80474-45-9 (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-m... 6a,9a-Difluoro-11--hydroxy-16-a-methyl-3-oxo-17-a-(propionyloxy)-androsta-1,4-diene-17--carbothioi TIANFU-CHEM FLUTICASONE PROPIONATE INTERMEDIATE Fluticasone intermediate FluticasoneImpurity3TriethylamineSalt 6alpha,9-Difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17-(propanoyloxy)androsta-1,4-diene-17beta-carbothioic Acid 6α,9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-propionyloxy-androsta-1,4-diene-17β-carbothioic acid Fluticasone Propionate Intermediate Impurity E 6α,9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(1-oxopropyloxy) androstene-1,4-diene-17β-thioformate Fluticasone propionate intermediate E (6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID 6α,9-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17-(propanoyloxy)androsta-1,4-diene-17β-carbothioic Acid (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carbothioic S-acid (6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-carbothioic acid Fn-1 80474-45-9 C24H30F2O5S C25H31BrF2O5S Intermediates & Fine Chemicals Pharmaceuticals Steroids

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