RDEA-594 sodiuM
- CAS No.
- 1151516-14-1
- Chemical Name:
- RDEA-594 sodiuM
- Synonyms
- CS-651;RDEA-594 sodiuM;Lesinurad sodiuM;Pentanedioicacid,5-oxo-,diethylester;sodium 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate;Sodium 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3- yl)sulfanyl)acetate;Acetic acid, 2-((5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl)thio)-, sodium salt;Acetic acid, 2-[[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt (1:1)
- CBNumber:
- CB22729369
- Molecular Formula:
- C17H13BrN3O2S.Na
- Molecular Weight:
- 426.26279
- MDL Number:
- MFCD24444603
- MOL File:
- 1151516-14-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Lesinurad sodium | BWB51614 | 10mg | $250 |
| Lesinurad sodium | BWB51614 | 25mg | $281.5 |
| Lesinurad sodium | BWB51614 | 50mg | $449.5 |
| Lesinurad sodium | BWB51614 | 100mg | $719 |
| Lesinurad sodium | BWB51614 | 250mg | $1350 |
| More product size | |||
| storage temp. | Store at -20°C |
|---|---|
| solubility |
DMSO:55.5(Max Conc. mg/mL);137.97(Max Conc. mM) Ethanol:85.0(Max Conc. mg/mL);199.41(Max Conc. mM) Water:8.0(Max Conc. mg/mL);18.77(Max Conc. mM) |
| form | Solid |
| color | White to off-white |
| FDA UNII | 25UH266CV3 |
RDEA-594 sodiuM price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | BWB51614 | Lesinurad sodium | 1151516-14-1 | 10mg | $250 | 2026-06-04 | Buy |
| Biosynth | BWB51614 | Lesinurad sodium | 1151516-14-1 | 25mg | $281.5 | 2026-06-04 | Buy |
| Biosynth | BWB51614 | Lesinurad sodium | 1151516-14-1 | 50mg | $449.5 | 2026-06-04 | Buy |
| Biosynth | BWB51614 | Lesinurad sodium | 1151516-14-1 | 100mg | $719 | 2026-06-04 | Buy |
| Biosynth | BWB51614 | Lesinurad sodium | 1151516-14-1 | 250mg | $1350 | 2026-06-04 | Buy |
RDEA-594 sodiuM Chemical Properties,Uses,Production
Uses
Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 μM, respectively.
in vivo
Lesinurad (RDEA594) shows better pharmacokinetics than its pro-drug RDEA806. The 100 mg dose of Lesinurad exhibits a phamacological effect in the range of that produced by 300 mg to 800 mg single doses of RDEA806[3].
References
[1] Shen Z, et al. In Vitro and In Vivo Interaction Studies Between Lesinurad, a Selective Urate Reabsorption Inhibitor, and Major Liver or Kidney Transporters. Clin Drug Investig. 2016 Jun;36(6):443-52 DOI:10.1037//0882-7974.4.4.471
[2] Sattui SE, et al. Treatment of hyperuricemia in gout: current therapeutic options, latest developments and clinical implications. Ther Adv Musculoskelet Dis. 2016 Aug;8(4):145-59. DOI:10.1177/1759720X16646703
[3] L.Yeh, et al. RDEA594, a potential uric acid lowering agent througn inhibition of uric acid reuptake ,shows better pharmacokinetics rhan its prodrug RDEA806. 2008 ACR/ARHP Annual Scientific Meeting, 24-29 October 2008, USA.
RDEA-594 sodiuM Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | +86-18600796368 | sales@sjar-tech.com | China | 529 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11680 | 58 |
View Lastest Price from RDEA-594 sodiuM manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-12 | Lesinurad Sodium
1151516-14-1
|
1g | More Than 99% | 100kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | ||
 |
2026-06-12 | Lesinurad Sodium.
1151516-14-1
|
1g | More Than 99% | 100kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | ||
 |
2026-04-22 | Lesinurad sodium
1151516-14-1
|
$31.00-47.00 | 99.97% | 10g | TargetMol Chemicals Inc. |
-
- Lesinurad Sodium
1151516-14-1
- $0.00
- More Than 99%
- BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
-
- Lesinurad Sodium.
1151516-14-1
- $0.00
- More Than 99%
- BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
-
- Lesinurad sodium
1151516-14-1
- $31.00-47.00
- 99.97%
- TargetMol Chemicals Inc.
