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ChemicalBook CAS DataBase List RDEA-594 sodiuM
1151516-14-1

RDEA-594 sodiuM synthesis

11synthesis methods
1533519-92-4 Synthesis
4-cyclopropylnaphthalen-1-aMine hydrochloride

1533519-92-4
162 suppliers
$6.00/250mg

RDEA-594 sodiuM

1151516-14-1
79 suppliers
inquiry

-

Yield:-

Steps:

Multi-step reaction with 6 steps
1: potassium hydroxide / dichloromethane
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
4: sodium carbonate / N,N-dimethyl-formamide / 27 - 35 °C / Large scale
5: N-Bromosuccinimide / tetrahydrofuran / 27 - 32 °C / Large scale
6: sodium hydroxide / toluene; water / 18 - 25 °C / Large scale

References:

ARDEA BIOSCIENCES, INC.;GUNIC, Esmir;GALVIN, Gabriel WO2014/8295, 2014, A1

1533519-84-4 Synthesis
4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

1533519-84-4
184 suppliers
$12.00/250mg

RDEA-594 sodiuM

1151516-14-1
79 suppliers
inquiry

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