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ChemicalBook >> CAS DataBase List >>MPT0E028

MPT0E028

CAS No.
1338320-94-7
Chemical Name:
MPT0E028
Synonyms
MPT0E028;MPT-0E028,MPT0E028;3-(1-Benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide;2-Propenamide, 3-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]-N-hydroxy-
CBNumber:
CB22731104
Molecular Formula:
C17H16N2O4S
Molecular Weight:
344.38
MDL Number:
MFCD32201064
MOL File:
1338320-94-7.mol
MSDS File:
SDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
3-(1-Benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide NDC32094 10mg $853.8
3-(1-Benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide NDC32094 25mg $1392
3-(1-Benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide NDC32094 50mg $2227
Imofinostat 99.40% CS-0086144 5mg $282
Imofinostat 99.40% CS-0086144 10mg $412

MPT0E028 Properties

Density 1.427±0.06 g/cm3(Predicted)
storage temp. 4°C, away from moisture and light
pka 8.97±0.23(Predicted)
form Solid
color White to off-white
FDA UNII T65L58FI65

MPT0E028 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth NDC32094 3-(1-Benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 1338320-94-7 10mg $853.8 2026-06-04 Buy
Biosynth NDC32094 3-(1-Benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 1338320-94-7 25mg $1392 2026-06-04 Buy
Biosynth NDC32094 3-(1-Benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 1338320-94-7 50mg $2227 2026-06-04 Buy
ChemScene CS-0086144 Imofinostat 99.40% 1338320-94-7 5mg $282 2026-06-04 Buy
ChemScene CS-0086144 Imofinostat 99.40% 1338320-94-7 10mg $412 2026-06-04 Buy
Product number Packaging Price Buy
NDC32094 10mg $853.8 Buy
NDC32094 25mg $1392 Buy
NDC32094 50mg $2227 Buy
CS-0086144 5mg $282 Buy
CS-0086144 10mg $412 Buy

MPT0E028 Chemical Properties,Uses,Production

Uses

MPT0E028 is an orally active and selective HDAC inhibitor with IC50s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2 and HDAC6, respectively[1]. MPT0E028 reduces the viability of B-cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B-cell lymphoma. MPT0E028 has good anticancer activity[2].

IC 50

HDAC1: 53.0 nM (IC50); HDAC2: 106.2 nM (IC50); HDAC6: 29.5 nM (IC50); HDAC8: 2532.6 nM (IC50)

References

[1] Huang HL, et al. Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo. PLoS One. 2012;7(8):e43645. DOI:10.1371/journal.pone.0043645
[2] Huang HL, et al. Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo. Oncotarget. 2015 Mar 10;6(7):4976-91. DOI:10.18632/oncotarget.3213

1011-65-0
1338320-94-7
Synthesis of MPT0E028 from Methyl indole-5-carboxylate

MPT0E028 Preparation Products And Raw materials

Raw materials

Preparation Products

MPT0E028 Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39040 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
Jingmo (Xiamen) Biotechnology Co., Ltd 13621943973; 13621943973 sales@jamxmpharmatech.com China 1185 58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd dexuanyiyao@126.com dexuanyiyao@126.com China 9475 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4940 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24958 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11972 58

View Lastest Price from MPT0E028 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Imofinostat pictures 2026-04-22 Imofinostat
1338320-94-7
$662.00-1730.00 99.24% 10g TargetMol Chemicals Inc.
  • Imofinostat pictures
  • Imofinostat
    1338320-94-7
  • $662.00-1730.00
  • 99.24%
  • TargetMol Chemicals Inc.
MPT0E028 MPT-0E028,MPT0E028 2-Propenamide, 3-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]-N-hydroxy- 3-(1-Benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 1338320-94-7
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