2-Chloro-5-fluoronicotinonitrile
- CAS No.
- 791644-48-9
- Chemical Name:
- 2-Chloro-5-fluoronicotinonitrile
- Synonyms
- 2-Chloro-5-fluoropyridine-3-carbonitrile;2-Chloro-5-fluoronicotinonitrile;2-Chloro-5-fluoro-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 2-chloro-5-fluoro-;2-Chloro-5-fluoronicotinonitrile ISO 9001:2015 REACH
- CBNumber:
- CB32516238
- Molecular Formula:
- C6H2ClFN2
- Molecular Weight:
- 156.54
- MDL Number:
- MFCD15526908
- MOL File:
- 791644-48-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 269046 | 500mg | $460 |
| 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 269046 | 1g | $772 |
| 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 269046 | 2g | $1097 |
| 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 269046 | 5g | $1805 |
| 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 269046 | 10g | $2654 |
| More product size | |||
| Boiling point | 235℃ |
|---|---|
| Density | 1.43 |
| Flash point | 96℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -4.51±0.10(Predicted) |
| form | solid |
| color | White to off-white |
| InChI | InChI=1S/C6H2ClFN2/c7-6-4(2-9)1-5(8)3-10-6/h1,3H |
| InChIKey | SUBZTZVHVGYOPM-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=C(F)C=C1C#N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| HS Code | 2933399990 |
2-Chloro-5-fluoronicotinonitrile price More Price(80)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 269046 | 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 791644-48-9 | 500mg | $460 | 2026-06-03 | Buy |
| Usbiological | 269046 | 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 791644-48-9 | 1g | $772 | 2026-06-03 | Buy |
| Usbiological | 269046 | 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 791644-48-9 | 2g | $1097 | 2026-06-03 | Buy |
| Usbiological | 269046 | 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 791644-48-9 | 5g | $1805 | 2026-06-03 | Buy |
| Usbiological | 269046 | 2-Chloro-3-cyano-5-fluoro pyridine Asreported | 791644-48-9 | 10g | $2654 | 2026-06-03 | Buy |
2-Chloro-5-fluoronicotinonitrile Chemical Properties,Uses,Production
Synthesis
75302-64-6
791644-48-9
Example 3A: Synthesis of 2-chloro-5-fluoronicotinonitrile 81.2 mL (582.25 mmol) of triethylamine was added to a 783 mL dichloromethane suspension containing 46.2 g (264.66 mmol) of 2-chloro-5-fluoronicotinonitrile, and the mixture was subsequently cooled to 0°C. Under continuous stirring, 41.12 mL (291.13 mmol) of trifluoroacetic anhydride was slowly added dropwise, and after completion of the dropwise addition, the reaction mixture was kept at 0 °C with continued stirring for 1.5 hours. After completion of the reaction, the reaction mixture was washed twice with saturated aqueous sodium bicarbonate (391 mL each time), and the organic phase was dried and concentrated under reduced pressure to give the crude product. The final product was 2-chloro-5-fluoronicotinonitrile with a yield of 42.1 g and 90% yield. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ= 8.66 (dd, 1H), 8.82 (d, 1H).
References
[1] Patent: WO2013/25958, 2013, A1. Location in patent: Page/Page column 57; 58
[2] Patent: TWI609011, 2017, B. Location in patent: Page/Page column 77; 78
[3] Patent: EP2680844, 2016, B1. Location in patent: Paragraph 0134
[4] Patent: EP2744501, 2016, B1. Location in patent: Paragraph 0164; 0166
[5] Patent: TW2018/8946, 2018, A. Location in patent: Page/Page column 67
2-Chloro-5-fluoronicotinonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8828 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9996 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9539 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from 2-Chloro-5-fluoronicotinonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-07-25 | 2-Chloro-5-fluoronicotinonitrile
791644-48-9
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
![]() |
2025-06-25 | 2-Chloro-5-fluoronicotinonitrile
791644-48-9
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd |
-

- 2-Chloro-5-fluoronicotinonitrile
791644-48-9
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- 2-Chloro-5-fluoronicotinonitrile
791644-48-9
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
791644-48-9(2-Chloro-5-fluoronicotinonitrile)Related Search:
1of4






