(E)-1,4-Dibromobut-2-ene
- CAS No.
- 821-06-7
- Chemical Name:
- (E)-1,4-Dibromobut-2-ene
- Synonyms
- trans-1,4-Dibromo-2-butene;Dibromobutene;4-DibroMo-2-butene;1,4-Dibromo-1-butene;(E)-1,4-Dibromobut-2;1,4-DIBROMO-2-PENTENE;4-dibromo-(e)-2-buten; 1,4-dibromo-, trans-;1,4-Dibromo-2-butene, E;4-dibromo-trans-2-buten
- CBNumber:
- CB3312702
- Molecular Formula:
- C4H6Br2
- Molecular Weight:
- 213.9
- MDL Number:
- MFCD07783464
- MOL File:
- 821-06-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| trans-1,4-Dibromo-2-butene 99% | D39207 | 25g | $108 |
| trans-1,4-Dibromo-2-butene 99% | D39207 | 100g | $137 |
| trans-1,4-Dibromo-2-butene | D2944 | 25G | $89 |
| trans-1,4-Dibromo-2-butene | D2944 | 250G | $442 |
| trans-1,4-Dibromo-2-butene Asreported | 270734 | 50g | $319 |
| More product size | |||
| Melting point | 48-51 °C(lit.) |
|---|---|
| Boiling point | 205 °C(lit.) |
| Density | 1.9393 (estimate) |
| refractive index | 1.5361 (estimate) |
| Flash point | 113°C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystals or Crystalline Powder |
| color | colorless to slightly brown |
| Water Solubility | slightly soluble |
| BRN | 1719696 |
| Stability | Light Sensitive |
| InChI | 1S/C4H6Br2/c5-3-1-2-4-6/h1-2H,3-4H2/b2-1+ |
| InChIKey | RMXLHIUHKIVPAB-OWOJBTEDSA-N |
| SMILES | BrC\C=C\CBr |
| CAS DataBase Reference | 821-06-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | 2-Butene, 1,4-dibromo-, (E)-(821-06-7) |
| EPA Substance Registry System | 2-Butene, 1,4-dibromo-, (2E)- (821-06-7) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H314 | |||||||||
| Precautionary statements | P260-P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T,C | |||||||||
| Risk Statements | 25-34-23/25 | |||||||||
| Safety Statements | 26-36/37/39-45-28A | |||||||||
| RIDADR | UN 2923 8/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | EM4725000 | |||||||||
| F | 8-19 | |||||||||
| Hazard Note | Toxic/Corrosive | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29033990 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
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| Hazard Classifications | Acute Tox. 3 Oral Skin Corr. 1B |
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| REACH Registrations | Active | |||||||||
| Limited Quantities | 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
(E)-1,4-Dibromobut-2-ene price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D39207 | trans-1,4-Dibromo-2-butene 99% | 821-06-7 | 25g | $108 | 2026-04-30 | Buy |
| Sigma-Aldrich | D39207 | trans-1,4-Dibromo-2-butene 99% | 821-06-7 | 100g | $137 | 2026-04-30 | Buy |
| TCI Chemical | D2944 | trans-1,4-Dibromo-2-butene | 821-06-7 | 25G | $89 | 2026-04-30 | Buy |
| TCI Chemical | D2944 | trans-1,4-Dibromo-2-butene | 821-06-7 | 250G | $442 | 2026-04-30 | Buy |
| Usbiological | 270734 | trans-1,4-Dibromo-2-butene Asreported | 821-06-7 | 50g | $319 | 2026-06-03 | Buy |
(E)-1,4-Dibromobut-2-ene Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
(2E)-1,4-Dibromo-2-butene, is used as a reagent in the preparation of diaminoalkenes though copper-mediated diamination reaction.
Synthesis Reference(s)
The Journal of Organic Chemistry, 36, p. 3324, 1971 DOI: 10.1021/jo00821a012
General Description
Crystals or white crystalline solid.
Air & Water Reactions
(E)-1,4-Dibromobut-2-ene may be sensitive to exposure to light and air. Insoluble in water.
Reactivity Profile
(E)-1,4-Dibromobut-2-ene is incompatible with strong oxidizers and strong bases.
Fire Hazard
(E)-1,4-Dibromobut-2-ene is probably combustible.
Synthesis
106-99-0
821-06-7
Example 1 (E)-1,4-dibromo-2-butene (A) Synthesis: 1,3-butadiene (60 mL, 0.70 mol) was added to a 500 mL round-bottomed flask and the flask was placed in a -78 °C cooling bath. Carbon tetrachloride (CCl4, 100 mL) pre-cooled to -20 °C was slowly added to the flask to ensure that the temperature of the reaction mixture was maintained below -20 °C. Subsequently, bromine was added dropwise over a period of 2 hours. The reaction mixture was stirred vigorously at room temperature for 14 hours. After completion of the reaction, most of the solvent was evaporated under reduced pressure. The crude product was purified by recrystallization from cold hexane to afford white crystalline 1,4-dibromo-2-butene (A) (62.4 g, 0.29 mmol) in 58% yield. Thin layer chromatography (TLC) showed an Rf value of 0.74 (unfolding agent ratio hexane:ethyl acetate = 4:1). Nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 300.40 MHz, CDCl3) data were as follows: δ 3.89-4.02 (m, 4H), 5.90-6.05 (m, 2H) ppm.
Purification Methods
Crystallise the dibromide from ligroin and/or distil it in a vacuum. [Beilstein 1 IV 79.]
References
[1] Journal of the American Chemical Society, 2014, vol. 136, # 43, p. 15403 - 15413
[2] Patent: US2008/262271, 2008, A1. Location in patent: Page/Page column 6
[3] Patent: WO2006/38764, 2006, A1. Location in patent: Page/Page column 9-10
[4] Chemische Berichte, 1938, vol. 71, p. 1679
[5] Angewandte Chemie, 1938, vol. 51, p. 919
(E)-1,4-Dibromobut-2-ene Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
View Lastest Price from (E)-1,4-Dibromobut-2-ene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-24 | (E)-1,4-Dibromobut-2-ene
821-06-7
|
$5.00 | 1kg | ≥99% | 100mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2026-07-09 | (E)-1,4-Dibromobut-2-ene
821-06-7
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-06-27 | (E)-1,4-Dibromobut-2-ene
821-06-7
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-
- (E)-1,4-Dibromobut-2-ene
821-06-7
- $5.00
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- (E)-1,4-Dibromobut-2-ene
821-06-7
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- (E)-1,4-Dibromobut-2-ene
821-06-7
- $0.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
