2,5-Dimethyl-2,5-hexanediol
- CAS No.
- 110-03-2
- Chemical Name:
- 2,5-Dimethyl-2,5-hexanediol
- Synonyms
- 2,5-DIMETHYLHEXANE-2,5-DIOL;2,5-Hexanediol, 2,5-dimethyl-;1,1,4,4-Tetramethyl-1,4-butanediol;nsc5595;ai3-20685;5-hexanediol;-2,5-hexanedioL;dimethylhexanediol;DiMethyl-2,5-hexan;2,5-Dimethyl-2,5-hex
- CBNumber:
- CB3335426
- Molecular Formula:
- C8H18O2
- Molecular Weight:
- 146.23
- MDL Number:
- MFCD00004473
- MOL File:
- 110-03-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2,5-Dimethyl-2,5-hexanediol 97% | 143618 | 100g | $53.5 |
| 2,5-Dimethyl-2,5-hexanediol 97% | 143618 | 500g | $111 |
| 2,5-Dimethyl-2,5-hexanediol >99.0%(GC) | D1167 | 25g | $25 |
| 2,5-Dimethyl-2,5-hexanediol >99.0%(GC) | D1167 | 500g | $78 |
| 2,5-Dimethyl-2,5-hexanediol | FD04241 | 2000g | $340 |
| More product size | |||
| Melting point | 86-90 °C (lit.) |
|---|---|
| Boiling point | 214-215 °C (lit.) |
| Density | 0,898 g/cm3 |
| vapor pressure | 0.18Pa at 20℃ |
| refractive index | 1.4429 (estimate) |
| Flash point | 126 °C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 15.07±0.29(Predicted) |
| form | Crystalline Flakes |
| color | White |
| Odor | mild camphor |
| Water Solubility | SOLUBLE |
| BRN | 1361437 |
| Henry's Law Constant | 1.4×101 mol/(m3Pa) at 25℃, Zhang et al. (2010) |
| InChI | 1S/C8H18O2/c1-7(2,9)5-6-8(3,4)10/h9-10H,5-6H2,1-4H3 |
| InChIKey | ZWNMRZQYWRLGMM-UHFFFAOYSA-N |
| SMILES | CC(C)(O)CCC(C)(C)O |
| LogP | 0.21 at 23℃ |
| CAS DataBase Reference | 110-03-2(CAS DataBase Reference) |
| FDA UNII | 3PNB2S8721 |
| NIST Chemistry Reference | 2,5-Hexanediol, 2,5-dimethyl-(110-03-2) |
| EPA Substance Registry System | 2,5-Hexanediol, 2,5-dimethyl- (110-03-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29053980 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| Hazardous Substances Data | 110-03-2(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
2,5-Dimethyl-2,5-hexanediol price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 143618 | 2,5-Dimethyl-2,5-hexanediol 97% | 110-03-2 | 100g | $53.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 143618 | 2,5-Dimethyl-2,5-hexanediol 97% | 110-03-2 | 500g | $111 | 2026-04-30 | Buy |
| TCI Chemical | D1167 | 2,5-Dimethyl-2,5-hexanediol >99.0%(GC) | 110-03-2 | 25g | $25 | 2026-04-30 | Buy |
| TCI Chemical | D1167 | 2,5-Dimethyl-2,5-hexanediol >99.0%(GC) | 110-03-2 | 500g | $78 | 2026-04-30 | Buy |
| Biosynth | FD04241 | 2,5-Dimethyl-2,5-hexanediol | 110-03-2 | 2000g | $340 | 2026-06-04 | Buy |
2,5-Dimethyl-2,5-hexanediol Chemical Properties,Uses,Production
Chemical Properties
Colorless or white crystalline flakes. M.P. 93°C. B.P. 213°C. Soluble in water (20°C 140g/L), miscible with alcohol and most oils. Faint, camphorlike odor.
Uses
2,5-Dimethyl-2,5-hexanediol is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane to produce polyethylene copolymers and polyethylene rubbers. It is also could be used to prepared nickel-containing Complex Reducing Agents (termed NiCRA)[1].
Uses
2,5-Dimethyl-2,5-hexanediol was used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.
Preparation
The raw materials 2,5-Dimethyl-3-hexyne-2,5-diol (37.4 g, 263 mmol), ethyl acetate (60 mL), and Pd/C catalyst (0.285 g, 2.63 mmol, 1 mol %) were added to an autoclave. The hydrogen gas was slowly added to 10 bar. When the hydrogenation reaction was performed for 12 hours and then removed the hydrogen gas. Finally, 2,5-Dimethyl-2,5-hexanediol is obtained by purification.
Synthesis Reference(s)
Synthesis, p. 165, 1981 DOI: 10.1055/s-1981-29377
General Description
2,5-Dimethyl-2,5-hexanediol on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.
Purification Methods
Purify the diol by fractional crystallisation. Then the diol is dissolved in hot acetone, treated with activated charcoal, and filtered while hot. The solution is cooled and the diol is filtered off and washed well with cold acetone. The crystallisation process ia repeated several times, and the crystals are dried under a vacuum in a freeze-drying apparatus [Goates et al. J Chem Soc, Faraday Trans 1 78 3045 1982]. [Beilstein 1 IV 2600.]
References
[1] Feghouli G, et al. Activation of reducing agents. Sodium hydride containing complex reducing agents 29. Epimerization of alcohols by nickel-containing complex reducing agents (NiCRA). Tetrahedron Letters, 1988; 9: 285–290.
2,5-Dimethyl-2,5-hexanediol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Suze Chemical Materials Co.,Ltd. | +86-0523-86392777 +86-19825580222 | nick.miao@suzechem.com | China | 23 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
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View Lastest Price from 2,5-Dimethyl-2,5-hexanediol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 2,5-Dimethyl-2,5-hexanediol
110-03-2
|
1KG | 99% | 500mt | Jinan Finer Chemical Co., Ltd | ||
 |
2026-05-28 | 2,5-Dimethyl-2,5-hexanediol
110-03-2
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | 2,5-Dimethyl-2,5-hexanediol
110-03-2
|
$1.00 | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 2,5-Dimethyl-2,5-hexanediol
110-03-2
- $0.00
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 2,5-Dimethyl-2,5-hexanediol
110-03-2
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 2,5-Dimethyl-2,5-hexanediol
110-03-2
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
