3-PyridineCarboxamide,Nevirapine
- CAS No.
- 133627-47-1
- Chemical Name:
- 3-PyridineCarboxamide,Nevirapine
- Synonyms
- Naproxen Impurity 49;Nevirapine Impurity 1;3-PyridineCarboxamide,Nevirapine;N-(2-chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)pyridine-3-carboxamide;N-(2-Chioro-4-Methyi-3-Pyndinyl)-2-(Cyclopropyi AMino)-3-Pyridine CarboxaMide;N-(2-Lhioro-4-Methyi-J-Pyndinyl)-2-(Cyclopropyi Amino)-3-Pyridine Carboxamide;3-Pyridinecarboxamide, N-(2-chloro-4-methyl-3-pyridinyl)-2-(cyclopropylamino)-
- CBNumber:
- CB41029082
- Molecular Formula:
- C15H15ClN4O
- Molecular Weight:
- 302.76
- MDL Number:
- MFCD15144663
- MOL File:
- 133627-47-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide | 097268 | 250.00mg | $189 |
| N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide | 097268 | 1.00g | $420 |
| N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide 95% | AD258542 | 250MG | $130 |
| N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide 95% | AD258542 | 1G | $345 |
| N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide 95+% | CD11292404 | 5g | $634 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
3-PyridineCarboxamide,Nevirapine price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 097268 | N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide | 133627-47-1 | 250.00mg | $189 | 2026-05-18 | Buy |
| Matrix Scientific | 097268 | N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide | 133627-47-1 | 1.00g | $420 | 2026-05-18 | Buy |
| ACHEMBLOCK | AD258542 | N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide 95% | 133627-47-1 | 250MG | $130 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD258542 | N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide 95% | 133627-47-1 | 1G | $345 | 2026-05-27 | Buy |
| Crysdot | CD11292404 | N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide 95+% | 133627-47-1 | 5g | $634 | 2026-05-26 | Buy |
3-PyridineCarboxamide,Nevirapine Chemical Properties,Uses,Production
Uses
N-(2-Chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide (CAS# 133627-47-1) is a synthetic intermediate and an impurity of nevirapine (N391275).
Synthesis
133627-45-9
765-30-0
133627-47-1
Example 7: Synthesis of N-(2-chloro-4-methyl-3-pyridinyl)-2-cyclopropylamino-3-pyridinecarboxamide (VII) In an autoclave, 2-chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide (III; 1.0 kg, 3.5587 mol) was dissolved in toluene (6.0 liters). Cyclopropylamine (0.813 kg, 14.23 mol) was then added and the reaction mixture was heated at 125 °C to 130 °C and 15 psi pressure for 21 hours. After completion of the reaction, the mixture was cooled to 25 °C to 30 °C and washed with distilled water. After separating the aqueous layer, the aqueous layer was extracted with ethyl acetate (2.0 liters). The organic layers (toluene and ethyl acetate layers) were combined and concentrated under reduced pressure to give the target product. Yield: 0.857 kg, yield: 79.64%, HPLC purity: 98.14%.
References
[1] Patent: WO2007/10352, 2007, A1. Location in patent: Page/Page column 20
3-PyridineCarboxamide,Nevirapine Preparation Products And Raw materials
Raw materials
Preparation Products
3-PyridineCarboxamide,Nevirapine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15079 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42056 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6777 | 52 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14435 | 57 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3979 | 55 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
View Lastest Price from 3-PyridineCarboxamide,Nevirapine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-11 | N-(2-chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)pyridine-3-carboxamide
133627-47-1
|
$9.80 | 1g | ＞98% | 20 tons | Career Henan Chemical Co |
-
- N-(2-chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)pyridine-3-carboxamide
133627-47-1
- $9.80
- ＞98%
- Career Henan Chemical Co
