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ChemicalBook >> CAS DataBase List >>MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

CAS No.
65144-34-5
Chemical Name:
MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
Synonyms
MEOSUC-AAPV-CMK;SPCK;HLE INHIBITOR;MEOSUC-APPV-CMK;ELASTASE INHIBITOR III;Elastase Inhibitor, SPCK;MEOSUC-ALA-ALA-PRO-VAL-CMK;N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.&;MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE;methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone
CBNumber:
CB4111744
Molecular Formula:
C22H35ClN4O7
Molecular Weight:
502.99
MDL Number:
MFCD00077136
MOL File:
65144-34-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone elastase inhibitor M0398 5mg $188
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone elastase inhibitor M0398 10mg $321
Elastase Inhibitor III The Elastase Inhibitor III controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. 324745 5MG $238
MeOSuc-Ala-Ala-Pro-Val-chloromethylketone FM111010 5mg $900
MeOSuc-Ala-Ala-Pro-Val-chloromethylketone FM111010 2mg $900

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Properties

Melting point 159-161 °C
Boiling point 809.4±65.0 °C(Predicted)
Density 1.234±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility ethanol: 50 mg/mL, clear, colorless
pka 13.05±0.20(Predicted)
form Solid
color white
Sensitive Moisture Sensitive
BRN 6167019
Sequence {MeOSuc}-Ala-Ala-Pro-Val-{CMK}
InChIKey PJGDFLJMBAYGGC-XLPNERPQSA-N
SMILES COC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)CCl
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
10
Storage Class 11 - Combustible Solids

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M0398 N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone elastase inhibitor 65144-34-5 5mg $188 2026-04-30 Buy
Sigma-Aldrich M0398 N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone elastase inhibitor 65144-34-5 10mg $321 2026-04-30 Buy
Sigma-Aldrich 324745 Elastase Inhibitor III The Elastase Inhibitor III controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. 5MG $238 2023-06-20 Buy
Biosynth FM111010 MeOSuc-Ala-Ala-Pro-Val-chloromethylketone 65144-34-5 5mg $900 2026-06-04 Buy
Biosynth FM111010 MeOSuc-Ala-Ala-Pro-Val-chloromethylketone 65144-34-5 2mg $900 2026-06-04 Buy
Product number Packaging Price Buy
M0398 5mg $188 Buy
M0398 10mg $321 Buy
324745 5MG $238 Buy
FM111010 5mg $900 Buy
FM111010 2mg $900 Buy

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Chemical Properties,Uses,Production

Uses

A potent irreversible inhibitor of human leukocyte elastase

Definition

ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone.

General Description

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

Biochem/physiol Actions

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Suppliers

Global( 83)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
16314854226; +8616314854226 inquiry@bocsci.com United States 19853 58
Nanjing TGpeptide
+86-13347807150 support@tgpeptide.com China 3279 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 +86-15355479329 market18@leapchem.com China 43333 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
TargetMol Chemicals Inc.
13564774135 marketing@targetmol.com United States 19956 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599 info@molchanges.com China 5218 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42934 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15402 60

View Lastest Price from MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MeOSuc-AAPV-CMK pictures 2026-07-27 MeOSuc-AAPV-CMK
65144-34-5
10g TargetMol Chemicals Inc.
N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE CHLOROMETHYLKETONE methoxysuccinyl-alanyl-alanyl-prolyl-valinechloromethylketone N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYL KETONE MEOSUC-APPV-CMK MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE MEOSUC-ALA-ALA-PRO-VAL-CMK ELASTASE INHIBITOR III HLE INHIBITOR N-(methoxysuccinyl)-L-ala-L-ala-L-prol.-L-val-chlorome.ket. N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL*CHLORO METHYL KETO N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.& N(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine CMK SPCK Elastase Inhibitor, SPCK methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-(1-methylethyl)-2-oxopropyl]- N-(4-Methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-(1-methylethyl)-2-oxopropyl]-L-prolinamide MEOSUC-AAPV-CMK 65144-34-5 C22H35ClN4O7 C22H35N4O7Cl Biochemicals and Reagents BioChemical Cell Biology Cell Signaling and Neuroscience Metalloproteinase Inhibitors Cytoskeleton and Extracellular Matrix Enzyme Inhibitors Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Extracellular Matrix Substrate Analogs ProteaseInhibitors
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