1-Acetyl-5-bromoindoline
- CAS No.
- 22190-38-1
- Chemical Name:
- 1-Acetyl-5-bromoindoline
- Synonyms
- 1-(5-Bromoindolin-1-yl)ethan-1-one;BUTTPARK 75\04-10;1-ACETYL-5-BROMOINDOLINE;5-bromo-N-acetylindoline;1-ACETYL-5-BROMOINDOLINE 98%;1-Acetyl-5-bromoindoline,98%;1-Acetyl-5-bromoindoline,97%;1-(5-bromoindolin-1-yl)ethanone;1-(5-bromo-1-indolinyl)ethanone;1-ACETYL-5-BROMO-2,3-DIHYDROINDOLE
- CBNumber:
- CB4114442
- Molecular Formula:
- C10H10BrNO
- Molecular Weight:
- 240.1
- MDL Number:
- MFCD00056017
- MOL File:
- 22190-38-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Acetyl-5-bromoindoline ≥99% | A6125 | 1g | $158 |
| 1-Acetyl-5-bromoindoline >98.0%(GC) | A2924 | 5g | $72 |
| 1-Acetyl-5-bromoindoline >98.0%(GC) | A2924 | 25g | $213 |
| 1-Acetyl-5-bromoindoline | FA52457 | 10g | $150 |
| 1-Acetyl-5-bromoindoline | FA52457 | 5g | $150 |
| Melting point | 118-121°C |
|---|---|
| Boiling point | 423.6±45.0 °C(Predicted) |
| Density | 1.529±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| form | powder to crystal |
| pka | 0.27±0.20(Predicted) |
| color | White to Yellow to Orange |
| BRN | 165052 |
| InChI | 1S/C10H10BrNO/c1-7(13)12-5-4-8-6-9(11)2-3-10(8)12/h2-3,6H,4-5H2,1H3 |
| InChIKey | WQKQAIXOTCPWFE-UHFFFAOYSA-N |
| SMILES | CC(=O)N1CCc2cc(Br)ccc12 |
| CAS DataBase Reference | 22190-38-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-52/53 | |||||||||
| Safety Statements | 26-36/37/39-61 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933998090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
1-Acetyl-5-bromoindoline price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A6125 | 1-Acetyl-5-bromoindoline ≥99% | 22190-38-1 | 1g | $158 | 2023-01-07 | Buy |
| TCI Chemical | A2924 | 1-Acetyl-5-bromoindoline >98.0%(GC) | 22190-38-1 | 5g | $72 | 2026-04-30 | Buy |
| TCI Chemical | A2924 | 1-Acetyl-5-bromoindoline >98.0%(GC) | 22190-38-1 | 25g | $213 | 2026-04-30 | Buy |
| Biosynth | FA52457 | 1-Acetyl-5-bromoindoline | 22190-38-1 | 10g | $150 | 2026-06-04 | Buy |
| Biosynth | FA52457 | 1-Acetyl-5-bromoindoline | 22190-38-1 | 5g | $150 | 2026-06-04 | Buy |
1-Acetyl-5-bromoindoline Chemical Properties,Uses,Production
Uses
1-Acetyl-5-bromoindoline is a valuable organic compound and could be used to synthesise 5-bromoindoline, 5-Bromo-7-nitroindoline, and others.
Synthesis
The synthesis method of 1-Acetyl-5-bromoindoline is as follows: add acetyl chloride (5.5 mmol, 1.1 equiv) to a stirred solution of 5-Bromoindolin (5 mmol, 1.0 equiv) and Et3N (7.5 mmol,1.5 equiv) in CH2Cl2 (15 mL) at 0°C. Stir the resulting mixture for 1 h under N2 atmosphere. Quench the reaction with NaHCO3 solution (20 mL). Separate the aqueous layer and wash with DCM (15 mL) and combine the organic layers. Dry the organicsolution over anhydrous Na2SO4 and evaporate under vacuum. Purify the residue by column chromatography on silica gel.
References
[1] ZHIYONG TAN*, WEI GUO* Visible Light Mediated Chemoselective Hydroxylation of Benzylic Methylenes[J]. The Journal of Organic Chemistry, 2024, 89 4: 2656-2664. DOI:10.1021/acs.joc.3c02683.
1-Acetyl-5-bromoindoline Preparation Products And Raw materials
Raw materials
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Preparation Products
1-Acetyl-5-bromoindoline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| sgtlifesciences pvt ltd | +91-8790379245 | dj@sgtlifesciences.com | China | 12373 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24597 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35425 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 12272 | 58 |
View Lastest Price from 1-Acetyl-5-bromoindoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 1-(5-Bromo-2,3-dihydro-1H-indol-1-yl)ethanone
22190-38-1
|
$1.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 1-(5-Bromo-2,3-dihydro-1H-indol-1-yl)ethanone
22190-38-1
- $1.00
- 98%
- Career Henan Chemical Co
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