(2-BROMO-PYRIDIN-4-YL)CARBAMIC ACID TERT-BUTYL ESTER
- CAS No.
- 433711-95-6
- Chemical Name:
- (2-BROMO-PYRIDIN-4-YL)CARBAMIC ACID TERT-BUTYL ESTER
- Synonyms
- Zinc02511835;(2-BROMO-PYRIDIN-4-Y;2-BROMO-4-BOC PYRIDINE;2-Bromo-4-N-Boc-aminopyridine;4-(BOC-AMINO)-2-BROMOPYRIDINE;N-Boc-4-amino-2-bromopyridine;2-Bromo-N-Boc-pyridin-4-amine;Tert-butyl 2-bromopyridin-4-ylcarbamate;tert-butyl N-(2-broMopyridin-4-yl)carbaMate;2-Bromo-4-(tert-butoxycarbonylamino)pyridine
- CBNumber:
- CB4125543
- Molecular Formula:
- C10H13BrN2O2
- Molecular Weight:
- 273.13
- MDL Number:
- MFCD03791266
- MOL File:
- 433711-95-6.mol
| Product description | Number | Pack Size | Price |
| (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester Aldrich | ADE000209 | 1g | $201 |
| 2-BROMO-4-N-BOC-AMINOPYRIDINE 97% | 56631 | 1G | $27 |
| (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester | 018201 | 5.00g | $81 |
| (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester | 018201 | 10.00g | $122 |
| (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester | 018201 | 25.00g | $302 |
| More product size | |||
| Boiling point | 299.3±25.0 °C(Predicted) |
|---|---|
| Density | 1.453±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 11.97±0.70(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 433711-95-6(CAS DataBase Reference) |
(2-BROMO-PYRIDIN-4-YL)CARBAMIC ACID TERT-BUTYL ESTER price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | ADE000209 | (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester Aldrich | 433711-95-6 | 1g | $201 | 2023-06-20 | Buy |
| AstaTech | 56631 | 2-BROMO-4-N-BOC-AMINOPYRIDINE 97% | 433711-95-6 | 1G | $27 | 2026-04-30 | Buy |
| Matrix Scientific | 018201 | (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester | 433711-95-6 | 5.00g | $81 | 2026-05-18 | Buy |
| Matrix Scientific | 018201 | (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester | 433711-95-6 | 10.00g | $122 | 2026-05-18 | Buy |
| Matrix Scientific | 018201 | (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester | 433711-95-6 | 25.00g | $302 | 2026-05-18 | Buy |
(2-BROMO-PYRIDIN-4-YL)CARBAMIC ACID TERT-BUTYL ESTER Chemical Properties,Uses,Production
Synthesis
7598-35-8
24424-99-5
433711-95-6
General procedure for the synthesis of 4-tert-butoxycarbonylamino-2-bromopyridine from 4-amino-2-bromopyridine and di-tert-butyl dicarbonate: 2-bromopyridin-4-amine (100.0 g), triethylamine (Et3N, 64.8 g), and dichloromethane (DCM, 1.0 L) were added to the reaction vial and the reaction mixture was stirred for 15-30 min at 20-30 °C. Subsequently, 4-dimethylaminopyridine (DMAP, 3.5 g) was added to the reaction vial and di-tert-butyl dicarbonate ((Boc)2O, 416.3 g) was added slowly and dropwise. The reaction mixture was stirred continuously at 20-30 °C for 16 h, during which the progress of the reaction was monitored by HPLC. After completion of the reaction, the reaction mixture was washed with deionized water (2 L). The organic phase was separated and concentrated under reduced pressure to give the crude product as a yellow solid. The solid was stirred with methanol (MeOH, 300.0 mL) at 20-30 °C for 30 min and then filtered to give 4-tert-butoxycarbonylamino-2-bromopyridine (171.2 g) as an off-white solid.
References
[1] Dalton Transactions, 2016, vol. 45, # 32, p. 12807 - 12813
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 24, p. 8709 - 8715
[3] Patent: US2003/119847, 2003, A1
[4] Patent: WO2017/137535, 2017, A1. Location in patent: Page/Page column 105
(2-BROMO-PYRIDIN-4-YL)CARBAMIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29093 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49895 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
View Lastest Price from (2-BROMO-PYRIDIN-4-YL)CARBAMIC ACID TERT-BUTYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | (2-BROMO-PYRIDIN-4-YL)CARBAMIC ACID TERT-BUTYL ESTER
433711-95-6
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-13 | 2-Bromo-4-N-Boc-aminopyridine
433711-95-6
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-03-08 | 2-Bromo-4-boc pyridine
433711-95-6
|
$10.00-100.00 | 1KG | Min98% HPLC | Career Henan Chemical Co |
-
- (2-BROMO-PYRIDIN-4-YL)CARBAMIC ACID TERT-BUTYL ESTER
433711-95-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-Bromo-4-N-Boc-aminopyridine
433711-95-6
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Bromo-4-boc pyridine
433711-95-6
- $10.00-100.00
- Min98% HPLC
- Career Henan Chemical Co
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