ChemicalBook >> CAS DataBase List >>1-Boc-4-methylpiperidine-4-carboxylic acid
1-Boc-4-methylpiperidine-4-carboxylic acid
- CAS No.
- 189321-63-9
- Chemical Name:
- 1-Boc-4-methylpiperidine-4-carboxylic acid
- Synonyms
- 1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid;1-BOC-4-METHYL-ISONIPECOTIC ACID;1-Boc-4-MethyL;CHEMBRDG-BB 4002933;-4-piperidinecarboxyL;N-BOC-4-METHYL ISONIPECOTIC ACID;4-METHYL-4-CARBOXY-1-N-BOC-PIPERIDINE;N-BOC-4-METHYL-4-PIPERIDINECARBOXYLIC ACID;1-Boc-4-methyl-4-piperidinecarboxylic Acid;1-BOC-4-Methyl-piperidin-4-carboxylic acid
- CBNumber:
- CB4192851
- Molecular Formula:
- C12H21NO4
- Molecular Weight:
- 243.3
- MDL Number:
- MFCD02179132
- MOL File:
- 189321-63-9.mol
- MSDS File:
- SDS
Last updated:2026-05-28 02:06:33
| Product description | Number | Pack Size | Price |
| 1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic Acid min. 98.0 % | B6385 | 1G | $51 |
| 1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic Acid min. 98.0 % | B6385 | 5G | $150 |
| 1-BOC-4-METHYL-ISONIPECOTIC ACID 97% | 64357 | 1G | $24 |
| 1-BOC-4-METHYL-ISONIPECOTIC ACID 97% | 64357 | 5G | $73 |
| 1-BOC-4-METHYL-ISONIPECOTIC ACID 97% | 64357 | 10G | $120 |
| More product size | |||
| Boiling point | 354.3±35.0 °C(Predicted) |
|---|---|
| Density | 1.129±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 4.69±0.20(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C12H21NO4/c1-11(2,3)17-10(16)13-7-5-12(4,6-8-13)9(14)15/h5-8H2,1-4H3,(H,14,15) |
| InChIKey | OKBNEDPOUYRYNP-UHFFFAOYSA-N |
| SMILES | N1(C(OC(C)(C)C)=O)CCC(C)(C(O)=O)CC1 |
| CAS DataBase Reference | 189321-63-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| RIDADR | UN2811 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
1-Boc-4-methylpiperidine-4-carboxylic acid price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B6385 | 1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic Acid min. 98.0 % | 189321-63-9 | 1G | $51 | 2026-04-30 | Buy |
| TCI Chemical | B6385 | 1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic Acid min. 98.0 % | 189321-63-9 | 5G | $150 | 2026-04-30 | Buy |
| AstaTech | 64357 | 1-BOC-4-METHYL-ISONIPECOTIC ACID 97% | 189321-63-9 | 1G | $24 | 2026-04-30 | Buy |
| AstaTech | 64357 | 1-BOC-4-METHYL-ISONIPECOTIC ACID 97% | 189321-63-9 | 5G | $73 | 2026-04-30 | Buy |
| AstaTech | 64357 | 1-BOC-4-METHYL-ISONIPECOTIC ACID 97% | 189321-63-9 | 10G | $120 | 2026-04-30 | Buy |
1-Boc-4-methylpiperidine-4-carboxylic acid Chemical Properties,Uses,Production
Chemical Properties
White to Light yellow powder to crystal
Synthesis
A mixture of Ethyl N-Boc-4-methylpiperidine-4-carboxylate (4.1 g, 15.1mmol) and lithium hydroxide (2.17g, 90.6mmol) in methanol (3OmL)ZH2O (2OmL) was stirred at a temperature of about 25 ℃ for 16h. After evaporation to dryness, the residue was partitioned between DCM and brine. The organic layer was separated, dried (MgSO4), filtered, and concentrated under reduced pressure to provide 3.38g of 1-Boc-4-methylpiperidine-4-carboxylic acid as a white solid (yield 92.0 percent).
References
[1] Patent: WO2008/89201, 2008, A2. Location in patent: Page/Page column 234
[2] Patent: US2010/137305, 2010, A1. Location in patent: Page/Page column 36
[3] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 14, p. 3675 - 3678
[4] Patent: US6083949, 2000, A
[5] Patent: EP854870, 2009, B1. Location in patent: Page/Page column 42
1-Boc-4-methylpiperidine-4-carboxylic acid Preparation Products And Raw materials
Global( 164)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5898 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10817 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
View Lastest Price from 1-Boc-4-methylpiperidine-4-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 1-Boc-4-methylpiperidine-4-carboxylic acid
189321-63-9
|
$2.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 1-Boc-4-methylpiperidine-4-carboxylic acid
189321-63-9
- $2.00
- 99%
- Career Henan Chemical Co
189321-63-9(1-Boc-4-methylpiperidine-4-carboxylic acid)Related Search:
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N-BOC-4-METHYL ISONIPECOTIC ACID
N-BOC-4-METHYL-4-METHYLPIPERIDINECARBOXYLIC ACID
N-BOC-4-METHYL-4-PIPERIDINECARBOXYLIC ACID
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1-Boc-4-methyl-4-piperidinecarboxylic Acid
N-BOC-4-METHYL-4-METHYLPIPERIDINECARBOXYLIC ACIDN-BOC-4-METHYL ISONIPECOTIC ACID
1-N-Boc-4-methyl-piperidine-4-carboxylic acid
1,4-Piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethylethyl) ester
1,4-piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethy
1-Boc-4-methyl-piperidine-4-carboxylic acid ,98%
1-(tert-butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid(SALTDATA: FREE)
N-Boc-4-Methyl-piperidine-4-carboxylic acid/
1-tert-butoxycarbonyl-4-methyl-isonipecotic acid
4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid
1-(tert-butoxy-oxomethyl)-4-methyl-4-piperidinecarboxylic acid
1-Boc-4-MethyL
-4-piperidinecarboxyL
4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylicaci
1-Boc-4-methylpiperidine-4-carboxylic acid USP/EP/BP
1,4-Piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethylethyl) ester (9CI, ACI)
4-methyl-1,4-Piperidinedicarboxylic acid 1-(1,1-dimethylethyl) ester (9CI ACI)
1-Boc-4-methyl-isonipecotic acid, CAS 189321-63-9
1-BOC-4-Methyl-piperidin-4-carboxylic acid
1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid
1-BOC-4-METHYL-ISONIPECOTIC ACID
189321-63-9
API intermediates
Amino Acids and Derivatives
Heterocycles
Pyridines
