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ChemicalBook >> CAS DataBase List >>1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-

1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-

CAS No.
253168-83-1
Chemical Name:
1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-
Synonyms
Apremilast Impurity 76;Apremilast Impurity 81;rac-Apremilast Impurity 11;2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-aminoisoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-;4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 4-amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-;((S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione (N- Deacetyl Apremilast)
CBNumber:
CB42715913
Molecular Formula:
C20H22N2O6S
Molecular Weight:
418.46
MDL Number:
MFCD32197151
MOL File:
253168-83-1.mol
MSDS File:
SDS
Last updated:2026-05-28 05:20:04
Product description Number Pack Size Price
4-Amino-2-[1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)Ethyl]-1H-Isoindole-1,3(2H)-Dione 95% AA00BJW5 25mg $120
4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione 97% W170541 25MG $185
4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione 97% W170541 100MG $555

1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Properties

Boiling point 673.6±55.0 °C(Predicted)
Density 1.383±0.06 g/cm3(Predicted)
pka -0.76±0.20(Predicted)
InChI InChI=1S/C20H22N2O6S/c1-4-28-17-10-12(8-9-16(17)27-2)15(11-29(3,25)26)22-19(23)13-6-5-7-14(21)18(13)20(22)24/h5-10,15H,4,11,21H2,1-3H3
InChIKey BHJUWEUNUCJYER-UHFFFAOYSA-N
SMILES C1(=O)C2=C(C(N)=CC=C2)C(=O)N1C(C1=CC=C(OC)C(OCC)=C1)CS(C)(=O)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00BJW5 4-Amino-2-[1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)Ethyl]-1H-Isoindole-1,3(2H)-Dione 95% 253168-83-1 25mg $120 2026-05-28 Buy
ACHEMBLOCK W170541 4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione 97% 253168-83-1 25MG $185 2026-05-27 Buy
ACHEMBLOCK W170541 4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione 97% 253168-83-1 100MG $555 2026-05-27 Buy
Product number Packaging Price Buy
AA00BJW5 25mg $120 Buy
W170541 25MG $185 Buy
W170541 100MG $555 Buy

1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Chemical Properties,Uses,Production

Uses

4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione is used in the apremilast acetylamino analogs preparation as oral PDE4 and TNF-α inhibitors.

1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Moldeep Biochemical Co., Ltd.
+86-25-58282389 +86-17351037455 inquiries@moldeep.com China 20000 58
Chongqing Chemieliva Pharmaceutical Co., Ltd. 18696571988 amy.lei@chemieliva.com China 1342 60
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9906 50
SPIRO PHARMA eric_feng1954@126.com China 9248 55
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
TOSUN PHARM 020-66392521-118 18922260391 3004261881@qq.com China 7985 58
Tianjin shijia biomedical technology co., LTD 15022261580 tjshj1212@163.com China 2749 58
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19689 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-aminoisoindoline-1,3-dione 1H-Isoindole-1,3(2H)-dione, 4-amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]- Apremilast Impurity 81 Apremilast Impurity 76 rac-Apremilast Impurity 11 4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione ((S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione (N- Deacetyl Apremilast) 253168-83-1
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