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3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE structure

CAS No.: 137628-16-1

Chemical Name:: 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE

Synonyms: 3-Bromo-5-chloro-2-pyridone;3-BROMO-5-CHLOROPYRIDIN-2-OL;3-Bromo-5-Chloro-2-Pyridinol;3-Bromo-5-chloropyridin-2-one;3-Bromo-5-chloro-2(1H)-pyridinone;3-bromo-5-chloropyridin-2(1H)-one;3-BROMO-5-CHLORO-2-HYDROXYPRIDINE;3-bromo-5-chloro-1H-pyridin-2-one;3-BROMO-5-CHLORO-2-HYDROXYPYRIDIN;2-hydro-5-chloro-3-bromo pyridine

CBNumber:: CB4369314

Molecular Formula:: C5H3BrClNO

Molecular Weight:: 208.44

MDL Number:: MFCD01764522

MOL File:: 137628-16-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 01:19:50

Product description	Number	Pack Size	Price
3-Bromo-5-chloropyridin-2(1h)-one >98%	OR926475	5g	$21
3-Bromo-5-chloropyridin-2(1h)-one >98%	OR926475	25g	$73
3-Bromo-5-chloropyridin-2(1h)-one >98%	OR926475	100g	$259
3-Bromo-5-chloropyridin-2(1h)-one >98%	OR926475	5g	$21
3-Bromo-5-chloropyridin-2(1h)-one >98%	OR926475	25g	$73

Request For Quotation

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Properties

Boiling point	277.6±40.0 °C(Predicted)
Density	1.91±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	8.48±0.10(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
HS Code	2933399990

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE price More Price(66)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR926475	3-Bromo-5-chloropyridin-2(1h)-one >98%	137628-16-1	5g	$21	2026-06-04	Buy
Apolloscientific	OR926475	3-Bromo-5-chloropyridin-2(1h)-one >98%	137628-16-1	25g	$73	2026-06-04	Buy
Apolloscientific	OR926475	3-Bromo-5-chloropyridin-2(1h)-one >98%	137628-16-1	100g	$259	2026-06-04	Buy
Apolloscientific	OR926475	3-Bromo-5-chloropyridin-2(1h)-one >98%	137628-16-1	5g	$21	2026-06-04	Buy
Apolloscientific	OR926475	3-Bromo-5-chloropyridin-2(1h)-one >98%	137628-16-1	25g	$73	2026-06-04	Buy

Product number	Packaging	Price	Buy
OR926475	5g	$21	Buy
OR926475	25g	$73	Buy
OR926475	100g	$259	Buy
OR926475	5g	$21	Buy
OR926475	25g	$73	Buy

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Chemical Properties,Uses,Production

Synthesis

4214-79-3

137628-16-1

General procedure for the synthesis of 2-hydroxy-5-chloro-3-bromopyridine from 5-chloropyridin-2-one: 5-chloro-2-hydroxypyridine (20.1 g, 155.4 mmol) and bromine (11.9 mL) were dissolved in acetic acid (250 mL), and the reaction was stirred for 2 hours at room temperature. Upon completion of the reaction, the solvent was removed by vacuum evaporation. The residue was extracted by adding ethyl acetate (600 mL) and saturated sodium bicarbonate solution (300 mL). The organic layer was washed sequentially with saturated sodium bicarbonate solution (2 x 200 mL) and brine, followed by drying and concentration with anhydrous sodium sulfate to give the crude product. The crude product was recrystallized by hexane/ether mixed solvent to afford purified 3-bromo-5-chloro-2-hydroxypyridine (21.3 g, 66% yield), which could be used directly in the subsequent reaction.

References

[1] Patent: WO2004/72037, 2004, A1. Location in patent: Page 11
[2] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 19, p. 2777 - 2782
[3] Patent: US5861419, 1999, A
[4] Patent: US6245797, 2001, B1
[5] Patent: WO2014/141110, 2014, A2. Location in patent: Page/Page column 83; 84

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Preparation Products And Raw materials

Raw materials

5-CHLORO-2-HYDROXYPYRIDINE Ethyl acetate Acetic acid Sodium bicarbonate

Preparation Products

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Suppliers

Global( 125)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29094	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58

Supplier	Advantage
Jinan Carbotang Biotech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
ANHUI WITOP BIOTECH CO., LTD	58
Dideu Industries Group Limited	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
sgtlifesciences pvt ltd	58

View Lastest Price from 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE 137628-16-1	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2020-01-18	3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE 137628-16-1	$3.00	1KG	98%	1kg , 5kg, 50kg	Career Henan Chemical Co

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE
137628-16-1
$1.10
99.00%
Dideu Industries Group Limited

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE
137628-16-1
$3.00
98%
Career Henan Chemical Co

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Spectrum

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE(137628-16-1)¹HNMR

137628-16-1(3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE)Related Search:

5-CHLORO-2-HYDROXYPYRIDINE 5-CHLORO-2-HYDROXYPYRIDINE 5-Bromo-2-chloro-3-hydroxypyridine 3-Bromo-2-methoxy-5-trifluoromethylpyridine 5-BROMO-3-CHLORO-2-HYDROXYPYRIDINE

5-BROMO-3-CHLORO-2-HYDROXYPYRIDINE 2-AMINO-4-BROMO-5-CHLORO-3-HYDROXYPYRIDINE 2-Bromo-3-chloro-5-hydroxypyridine 2-Bromo-5-chloro-3-hydroxypyridine 3-Bromo-2-chloro-5-hydroxypyridine

2-AMINO-5-BROMO-4-CHLORO-3-HYDROXYPYRIDINE 3-Bromo-5-chloropyridine 3-Bromo-2-hydroxypyridine 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE

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3-BROMO-5-CHLORO-2-HYDROXYPRIDINE 2-HYDROXY-3-BROMO-5-CHLOROPYRIDINE 3-BROMO-5-CHLOROPYRIDIN-2-OL 3-bromo-5-chloropyridin-2(1H)-one 3-Bromo-5-chloro-2(1H)-pyridinone 3-Bromo-5-chloro-2-pyridone 3-Bromo-5-chloropyridin-2-one 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE 3-bromo-5-chloro-1H-pyridin-2-one 2(1H)-Pyridinone, 3-bromo-5-chloro- 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE ISO 9001：2015 REACH 3-Bromo-5-Chloro-2-Pyridinol 3-BROMO-5-CHLORO-2-HYDROXYPYRIDIN 2-hydro-5-chloro-3-bromo pyridine 2-hydroxy 5-chloro 3-bromo pyridine 137628-16-1 37628-16-1 C5H3BrClNO Pyridine Series Pyridine Halides Pyridines

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