4-FLUORO-3-NITROBENZALDEHYDE
- CAS No.
- 42564-51-2
- Chemical Name:
- 4-FLUORO-3-NITROBENZALDEHYDE
- Synonyms
- uoro-3-nitrobenzaL;4-FLUORO-3-NITROBENZALDEHYDE;3-NITRO-4-FLUOROBENZALDEHYDE;2-Fluoro-5-formylnitrobenzene;Benzaldehyde, 4-fluoro-3-nitro-;4-Fluoro-3-nitrobenzaldehyde >4-Fluoro-3-nitrobenzaldehyde,97%;4-Fluoro-3-nitrobenzaldehyde 97%;4-Fluoro-3-nitrobenzaldehyde≥ 98% (GC)
- CBNumber:
- CB4402462
- Molecular Formula:
- C7H4FNO3
- Molecular Weight:
- 169.11
- MDL Number:
- MFCD01861388
- MOL File:
- 42564-51-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Fluoro-3-nitrobenzaldehyde 97% | 518301 | 1g | $68.6 |
| 4-Fluoro-3-nitrobenzaldehyde >95.0%(GC) | F0956 | 1g | $18 |
| 4-Fluoro-3-nitrobenzaldehyde >95.0%(GC) | F0956 | 5g | $51 |
| 4-Fluoro-3-nitrobenzaldehyde Asreported | 276066 | 5g | $307 |
| 4-Fluoro-3-nitrobenzaldehyde Asreported | 276066 | 10g | $408 |
| More product size | |||
| Melting point | 45-47 °C (lit.) |
|---|---|
| Boiling point | 286.0±25.0 °C(Predicted) |
| Density | 1.443±0.06 g/cm3(Predicted) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Crystalline Powder |
| color | White to tan |
| Sensitive | Air Sensitive |
| InChI | InChI=1S/C7H4FNO3/c8-6-2-1-5(4-10)3-7(6)9(11)12/h1-4H |
| InChIKey | ILKWFRCNNILIJW-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC=C(F)C([N+]([O-])=O)=C1 |
| CAS DataBase Reference | 42564-51-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-22 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29130000 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| NFPA 704 |
|
4-FLUORO-3-NITROBENZALDEHYDE price More Price(76)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 518301 | 4-Fluoro-3-nitrobenzaldehyde 97% | 42564-51-2 | 1g | $68.6 | 2023-06-20 | Buy |
| TCI Chemical | F0956 | 4-Fluoro-3-nitrobenzaldehyde >95.0%(GC) | 42564-51-2 | 1g | $18 | 2026-04-30 | Buy |
| TCI Chemical | F0956 | 4-Fluoro-3-nitrobenzaldehyde >95.0%(GC) | 42564-51-2 | 5g | $51 | 2026-04-30 | Buy |
| Usbiological | 276066 | 4-Fluoro-3-nitrobenzaldehyde Asreported | 42564-51-2 | 5g | $307 | 2026-06-03 | Buy |
| Usbiological | 276066 | 4-Fluoro-3-nitrobenzaldehyde Asreported | 42564-51-2 | 10g | $408 | 2026-06-03 | Buy |
4-FLUORO-3-NITROBENZALDEHYDE Chemical Properties,Uses,Production
Chemical Properties
White to tan crystalline powder
Uses
4-Fluoro-3-nitrobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
20274-69-5
42564-51-2
General procedure for the synthesis of 4-fluoro-3-nitrobenzaldehyde from 3-nitro-4-fluorobenzyl alcohol: a dimethyl sulfoxide (12 mL) suspension of the pyridine-sulfur trioxide complex (4.65 g, 29.2 mmol) was added to a solution containing 4-fluoro-3-nitrobenzyl alcohol (1.0 g, 5.84 mmol) and triethylamine (4.07 mL, 29.2 mmol) in a dichloromethane (20 mL) solution. The reaction mixture was stirred at room temperature for 15 minutes. After completion of the reaction, the reaction solution was diluted with ether (150 mL), washed sequentially with water, 5% potassium bisulfate solution and water, and the organic layer was dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure. The residue was purified by silica gel column chromatography [eluent: hexane-ethyl acetate (5:1)] to afford colorless crystalline 4-fluoro-3-nitrobenzaldehyde (0.86 g, 87% yield). The melting point of the product was 37-38 °C. 1H-NMR (CDCl3) δ: 7.51 (1H, t, J = 9.4 Hz), 8.10-8.30 (1H, m), 8.60 (1H, dd, J = 7.4, 2.2 Hz), 10.05 (1H, s).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 23, p. 5546 - 5550
[2] Patent: US2003/78251, 2003, A1
[3] Patent: WO2015/57938, 2015, A1. Location in patent: Page/Page column 52
[4] Patent: CN107400092, 2017, A. Location in patent: Paragraph 0293; 0295; 0300-0302
[5] Patent: CN108264511, 2018, A. Location in patent: Paragraph 0280; 0283; 0288-0290
4-FLUORO-3-NITROBENZALDEHYDE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3969 | 58 |
View Lastest Price from 4-FLUORO-3-NITROBENZALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-02 | 4-Fluoro-3-nitrobenzaldehyde
42564-51-2
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
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2026-02-02 | 4-Fluoro-3-nitrobenzaldehyde
42564-51-2
|
10mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
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2019-07-06 | 4-FLUORO-3-NITROBENZALDEHYDE
42564-51-2
|
$1.00 | 1KG | 98% | 1kg,5kg,100kg | Career Henan Chemical Co |
-

- 4-Fluoro-3-nitrobenzaldehyde
42564-51-2
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 4-Fluoro-3-nitrobenzaldehyde
42564-51-2
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-

- 4-FLUORO-3-NITROBENZALDEHYDE
42564-51-2
- $1.00
- 98%
- Career Henan Chemical Co
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