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ChemicalBook >> CAS DataBase List >>4-FLUORO-3-NITROBENZALDEHYDE

4-FLUORO-3-NITROBENZALDEHYDE

CAS No.
42564-51-2
Chemical Name:
4-FLUORO-3-NITROBENZALDEHYDE
Synonyms
uoro-3-nitrobenzaL;4-FLUORO-3-NITROBENZALDEHYDE;3-NITRO-4-FLUOROBENZALDEHYDE;2-Fluoro-5-formylnitrobenzene;Benzaldehyde, 4-fluoro-3-nitro-;4-Fluoro-3-nitrobenzaldehyde >4-Fluoro-3-nitrobenzaldehyde,97%;4-Fluoro-3-nitrobenzaldehyde 97%;4-Fluoro-3-nitrobenzaldehyde≥ 98% (GC)
CBNumber:
CB4402462
Molecular Formula:
C7H4FNO3
Molecular Weight:
169.11
MDL Number:
MFCD01861388
MOL File:
42564-51-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:27:40
Product description Number Pack Size Price
4-Fluoro-3-nitrobenzaldehyde 97% 518301 1g $68.6
4-Fluoro-3-nitrobenzaldehyde >95.0%(GC) F0956 1g $18
4-Fluoro-3-nitrobenzaldehyde >95.0%(GC) F0956 5g $51
4-Fluoro-3-nitrobenzaldehyde Asreported 276066 5g $307
4-Fluoro-3-nitrobenzaldehyde Asreported 276066 10g $408
More product size

4-FLUORO-3-NITROBENZALDEHYDE Properties

Melting point 45-47 °C (lit.)
Boiling point 286.0±25.0 °C(Predicted)
Density 1.443±0.06 g/cm3(Predicted)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Crystalline Powder
color White to tan
Sensitive Air Sensitive
InChI InChI=1S/C7H4FNO3/c8-6-2-1-5(4-10)3-7(6)9(11)12/h1-4H
InChIKey ILKWFRCNNILIJW-UHFFFAOYSA-N
SMILES C(=O)C1=CC=C(F)C([N+]([O-])=O)=C1
CAS DataBase Reference 42564-51-2(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38-22
Safety Statements  26-36/37/39-22
WGK Germany  3
HS Code  29130000
Storage Class 13 - Non Combustible Solids
NFPA 704
1
2 0

4-FLUORO-3-NITROBENZALDEHYDE price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 518301 4-Fluoro-3-nitrobenzaldehyde 97% 42564-51-2 1g $68.6 2023-06-20 Buy
TCI Chemical F0956 4-Fluoro-3-nitrobenzaldehyde >95.0%(GC) 42564-51-2 1g $18 2026-04-30 Buy
TCI Chemical F0956 4-Fluoro-3-nitrobenzaldehyde >95.0%(GC) 42564-51-2 5g $51 2026-04-30 Buy
Usbiological 276066 4-Fluoro-3-nitrobenzaldehyde Asreported 42564-51-2 5g $307 2026-06-03 Buy
Usbiological 276066 4-Fluoro-3-nitrobenzaldehyde Asreported 42564-51-2 10g $408 2026-06-03 Buy
Product number Packaging Price Buy
518301 1g $68.6 Buy
F0956 1g $18 Buy
F0956 5g $51 Buy
276066 5g $307 Buy
276066 10g $408 Buy

4-FLUORO-3-NITROBENZALDEHYDE Chemical Properties,Uses,Production

Chemical Properties

White to tan crystalline powder

Uses

4-Fluoro-3-nitrobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

4-FLUORO-3-NITROBENZYL ALCOHOL  96

20274-69-5

4-FLUORO-3-NITROBENZALDEHYDE

42564-51-2

General procedure for the synthesis of 4-fluoro-3-nitrobenzaldehyde from 3-nitro-4-fluorobenzyl alcohol: a dimethyl sulfoxide (12 mL) suspension of the pyridine-sulfur trioxide complex (4.65 g, 29.2 mmol) was added to a solution containing 4-fluoro-3-nitrobenzyl alcohol (1.0 g, 5.84 mmol) and triethylamine (4.07 mL, 29.2 mmol) in a dichloromethane (20 mL) solution. The reaction mixture was stirred at room temperature for 15 minutes. After completion of the reaction, the reaction solution was diluted with ether (150 mL), washed sequentially with water, 5% potassium bisulfate solution and water, and the organic layer was dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure. The residue was purified by silica gel column chromatography [eluent: hexane-ethyl acetate (5:1)] to afford colorless crystalline 4-fluoro-3-nitrobenzaldehyde (0.86 g, 87% yield). The melting point of the product was 37-38 °C. 1H-NMR (CDCl3) δ: 7.51 (1H, t, J = 9.4 Hz), 8.10-8.30 (1H, m), 8.60 (1H, dd, J = 7.4, 2.2 Hz), 10.05 (1H, s).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 23, p. 5546 - 5550
[2] Patent: US2003/78251, 2003, A1
[3] Patent: WO2015/57938, 2015, A1. Location in patent: Page/Page column 52
[4] Patent: CN107400092, 2017, A. Location in patent: Paragraph 0293; 0295; 0300-0302
[5] Patent: CN108264511, 2018, A. Location in patent: Paragraph 0280; 0283; 0288-0290

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View Lastest Price from 4-FLUORO-3-NITROBENZALDEHYDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Fluoro-3-nitrobenzaldehyde pictures 2026-07-02 4-Fluoro-3-nitrobenzaldehyde
42564-51-2
$3.00-9.00 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-Fluoro-3-nitrobenzaldehyde pictures 2026-02-02 4-Fluoro-3-nitrobenzaldehyde
42564-51-2
10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
4-FLUORO-3-NITROBENZALDEHYDE pictures 2019-07-06 4-FLUORO-3-NITROBENZALDEHYDE
42564-51-2
$1.00 1KG 98% 1kg,5kg,100kg Career Henan Chemical Co
4-FLUORO-3-NITROBENZALDEHYDE 4-Fluoro-3-nitrobenzaldehyde≥ 98% (GC) 4-Fluoro-3-nitrobenzaldehyde 97% 3-NITRO-4-FLUOROBENZALDEHYDE 4-Fluoro-3-nitrobenzaldehyde,97% 2-Fluoro-5-formylnitrobenzene 4-Fluoro-3-nitrobenzaldehyde > uoro-3-nitrobenzaL Benzaldehyde, 4-fluoro-3-nitro- 42564-51-2 42564-51-3 C7H4FO3 Organic Building Blocks Building Blocks Aldehydes Carbonyl Compounds C7 Halogenated Heterocycles ,Imidazoles ,Imidazolines/Imidazolidines Fluorine series Aromatic Aldehydes & Derivatives (substituted) Aldehydes C7 Carbonyl Compounds
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