Copper(II) gluconate
- CAS No.
- 527-09-3
- Chemical Name:
- Copper(II) gluconate
- Synonyms
- COPPER GLUCONATE;CUPRIC GLUCONATE;copper di-D-gluconate;COPPER GLUCONATE POWDER;Copper(II) glucote;COPPERGLUCONATE,FCC;COPPERGLUCONATE,USP;Glucose acid copper;COPPER(II) GLUCONATE;D-Gluconic acid copp
- CBNumber:
- CB4437183
- Molecular Formula:
- C12H22CuO14
- Molecular Weight:
- 453.84
- MDL Number:
- MFCD00075297
- MOL File:
- 527-09-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Copper(II) D-gluconate 98% | 344419 | 100g | $68 |
| Copper(II) Gluconate >97.0%(T) | G0275 | 25g | $17 |
| Copper(II) Gluconate >97.0%(T) | G0275 | 100g | $46 |
| D-Gluconic acid copper (II) salt | MG07603 | 2kg | $343.76 |
| D-Gluconic acid copper (II) salt | MG07603 | 5kg | $715 |
| More product size | |||
| Melting point | 155-157 °C(lit.) |
|---|---|
| Boiling point | 673.6℃[at 101 325 Pa] |
| Density | 1.777[at 20℃] |
| vapor pressure | 13.3Pa at 20℃ |
| refractive index | 16.5 ° (C=1, H2O) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Aqueous Acid (Slightly), Water (Sparingly, Sonicated) |
| form | powder |
| color | Light Blue to Blue |
| optical activity | [α]26/D +15°, c = 1 in H2O |
| Water Solubility | slightly soluble |
| Merck | 14,2640 |
| Exposure limits |
ACGIH: TWA 1 mg/m3 NIOSH: IDLH 100 mg/m3; TWA 1 mg/m3 |
| Stability | Hygrscopic |
| Cosmetics Ingredients Functions |
SKIN PROTECTING SKIN CONDITIONING |
| Cosmetic Ingredient Review (CIR) | Copper(II) gluconate (527-09-3) |
| InChI | 1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1 |
| InChIKey | OCUCCJIRFHNWBP-IYEMJOQQSA-L |
| SMILES | OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)O[Cu]OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO |
| LogP | -2.98 |
| CAS DataBase Reference | 527-09-3(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | COPPER GLUCONATE |
| EWG's Food Scores | 2 |
| FDA UNII | RV823G6G67 |
| NCI Drug Dictionary | copper gluconate |
| EPA Substance Registry System | Copper gluconate (527-09-3) |
| UNSPSC Code | 12352302 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P280-P362+P364-P301+P312+P330-P302+P352+P312-P304+P340+P312 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LZ5058000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29181600 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 2 Skin Sens. 1B STOT RE 2 |
|||||||||
| Hazardous Substances Data | 527-09-3(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Copper(II) gluconate price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 344419 | Copper(II) D-gluconate 98% | 527-09-3 | 100g | $68 | 2026-04-30 | Buy |
| TCI Chemical | G0275 | Copper(II) Gluconate >97.0%(T) | 527-09-3 | 25g | $17 | 2026-04-30 | Buy |
| TCI Chemical | G0275 | Copper(II) Gluconate >97.0%(T) | 527-09-3 | 100g | $46 | 2026-04-30 | Buy |
| Biosynth | MG07603 | D-Gluconic acid copper (II) salt | 527-09-3 | 2kg | $343.76 | 2026-06-04 | Buy |
| Biosynth | MG07603 | D-Gluconic acid copper (II) salt | 527-09-3 | 5kg | $715 | 2026-06-04 | Buy |
Copper(II) gluconate Chemical Properties,Uses,Production
Description
Copper(II) gluconate is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram.
References
Dicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.
Chemical Properties
Copper(II) gluconate, Cu(C6H11O7)2, is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol.
Uses
copper gluconate is cited as having skin-conditioning and skinprotecting functions.
Uses
Supplement (trace mineral).
Uses
Copper(II) gluconate is used in dietary supplement. It is also used to treat acne vulgaris, common cold, hypertension, premature labor, leishmaniasis and visceral postoperative complications. Further, it is used in oral deodorants and feed additives. In addition to this, it is used as a synergist and nutritional supplement for foods. It is the active component in retsyn used in mints and certs.
Preparation
Copper(II) gluconate is prepared by the dissolution of copper(II) carbonate or copper(II) hydroxide in gluconic acid. It is used as a nutritional supplement for copper deficiency and as a component in oral deodorants.
Definition
ChEBI: Copper gluconate is an organic molecular entity.
Flammability and Explosibility
Not classified
Safety Profile
When heated to decomposition it emits acrid smoke and irritating fumes.
Copper(II) gluconate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 | L18532138899@163.com | China | 939 | 58 |
| Lianyungang Kaiyu Environmental Tech Co., Ltd. | +86-0086-19851820538 +8619851820538 | carlos@khonorchem.com | China | 314 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
View Lastest Price from Copper(II) gluconate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-05 | Copper(II) gluconate
527-09-3
|
1kg | 98%-102% | 10000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-05-11 | Copper(II) gluconate
527-09-3
|
$33.00 | 99.99% | 10g | TargetMol Chemicals Inc. | ||
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2026-03-20 | Copper Gluconate
527-09-3
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-

- Copper(II) gluconate
527-09-3
- 98%-102%
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Copper(II) gluconate
527-09-3
- $33.00
- 99.99%
- TargetMol Chemicals Inc.
-

- Copper Gluconate
527-09-3
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd





