ChemicalBook >> CAS DataBase List >>Benzothiophene-3-boronic acid
Benzothiophene-3-boronic acid
- CAS No.
- 113893-08-6
- Chemical Name:
- Benzothiophene-3-boronic acid
- Synonyms
- AKOS BRN-0283;Benzo[b]thien-3-yL;ASDI-INTER 500027787;THIANAPHTHENE-3-BORONIC ACID;BENZOTHIOPHENE-3-BORONIC ACID;Thianaphthen-3-ylboronic acid;Benzo[b]thien-3-ylboronic acid;1-Benzothiophene-3-boronic Acid;Benzo[b]thiophen-3-ylboronicaci;Benzothiophene-3-ylboronic acid
- CBNumber:
- CB4460512
- Molecular Formula:
- C8H7BO2S
- Molecular Weight:
- 178.02
- MDL Number:
- MFCD01114669
- MOL File:
- 113893-08-6.mol
- MSDS File:
- SDS
Last updated:2026-05-28 01:23:46
| Product description | Number | Pack Size | Price |
| Benzo[b]thien-3-ylboronic acid ≥95.0% | 512117 | 5g | $116 |
| Benzo[b]thien-3-ylboronic acid ≥95.0% | 512117 | 25g | $420 |
| Benzo[b]thiophene-3-boronic Acid (contains varying amounts of Anhydride) | B4774 | 1g | $43 |
| Benzo[b]thiophene-3-boronic Acid (contains varying amounts of Anhydride) | B4774 | 5g | $131 |
| Benzo[b]thiophene-3-boronic acid Asreported | 264555 | 250mg | $336 |
| More product size | |||
| Melting point | 225-230 °C(lit.) |
|---|---|
| Boiling point | 390.2±34.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| pka | 8.29±0.30(Predicted) |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C8H7BO2S/c10-9(11)7-5-12-8-4-2-1-3-6(7)8/h1-5,10-11H |
| InChIKey | QVANIYYVZZLQJP-UHFFFAOYSA-N |
| SMILES | B(C1=CSC2=CC=CC=C21)(O)O |
| CAS DataBase Reference | 113893-08-6(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 29349990 |
| Storage Class | 11 - Combustible Solids |
Benzothiophene-3-boronic acid price More Price(87)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 512117 | Benzo[b]thien-3-ylboronic acid ≥95.0% | 113893-08-6 | 5g | $116 | 2026-04-30 | Buy |
| Sigma-Aldrich | 512117 | Benzo[b]thien-3-ylboronic acid ≥95.0% | 113893-08-6 | 25g | $420 | 2023-06-20 | Buy |
| TCI Chemical | B4774 | Benzo[b]thiophene-3-boronic Acid (contains varying amounts of Anhydride) | 113893-08-6 | 1g | $43 | 2026-04-30 | Buy |
| TCI Chemical | B4774 | Benzo[b]thiophene-3-boronic Acid (contains varying amounts of Anhydride) | 113893-08-6 | 5g | $131 | 2026-04-30 | Buy |
| Usbiological | 264555 | Benzo[b]thiophene-3-boronic acid Asreported | 113893-08-6 | 250mg | $336 | 2026-06-03 | Buy |
Benzothiophene-3-boronic acid Chemical Properties,Uses,Production
Uses
Benzo[b]thien-3-ylboronic acid can be used:
- To prepare thienyl substitutedpyrimidine derivatives as potent antimycobacterialcompounds.
- To prepare 3-O-protected 17-heteroaryl-3-hydroxyestra-1,3,5,16-tetraene-16-carbaldehyde, which in turn is used for the synthesis of heteroarenes-annelated estranes.
- As a substrate in the study of metal-free coupling reactions of allylic alcohols with heteroaryl boronic acids.
- As a starting material for the preparation of thienyl based quinoline and pyridine ligands, which are further used to synthesize platinum complexes.
Synthesis
7342-82-7
5419-55-6
113893-08-6
Under nitrogen protection, 10 g (47 mmol) of 3-bromobenzothiophene was dissolved in 100 ml of tetrahydrofuran (THF) and cooled to -60 °C. 36 ml of hexane solution of n-butyllithium (concentration 1.57 mol/L) was slowly added dropwise, and after the dropwise addition, the reaction mixture was continued to be stirred for 1 hour. Subsequently, 13.3 g (71 mmol) of triisopropyl borate was added and stirring was continued for 1 hour. The reaction system was slowly brought back to room temperature and the reaction was quenched by the addition of 50 ml of saturated aqueous ammonium chloride solution. The reaction mixture was extracted with 100 ml of toluene, the organic phase was washed three times (100 ml each) with distilled water and dried over anhydrous magnesium sulfate. The desiccant was removed by filtration and the solvent was removed by concentration under reduced pressure to afford intermediate B-1. 6.9 g (39 mmol, 83% yield) of the target product, benzothiophene-3-boronic acid, was finally obtained.
References
[1] Patent: EP2617724, 2013, A1. Location in patent: Paragraph 0162; 0163
[2] Patent: EP2628743, 2013, A1. Location in patent: Paragraph 0175
Benzothiophene-3-boronic acid Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
Global( 240)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1085 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
| Beijing Green Guardee Technology Co., Ltd | 86-010-69706062 | sales2@greenguardee.com | CHINA | 650 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| BAYNOE CHEM CO.,LTD | +86-21-34783353 +8615000719740 | baynoe@baynoe.com | CHINA | 934 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from Benzothiophene-3-boronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-02 | Benzothiophene-3-boronic acid
113893-08-6
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
![Benzo[b]thiophen-3-ylboronic acid pictures](/ProductImageEN/2023-09/Small/c20dc6e9-3c74-4419-ba85-cc5c36135645.jpg) |
2025-06-20 | Benzo[b]thiophen-3-ylboronic acid
113893-08-6
|
1kg | 0.99 | 100kg | Hebei Yanxi Chemical Co., Ltd. | ||
 |
2025-05-23 | Benzothiophene-3-boronic acid
113893-08-6
|
$10.00 | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- Benzothiophene-3-boronic acid
113893-08-6
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Benzo[b]thiophen-3-ylboronic acid
113893-08-6
- $0.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- Benzothiophene-3-boronic acid
113893-08-6
- $10.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
113893-08-6(Benzothiophene-3-boronic acid)Related Search:
AKOS BRN-0283
1-BENZOTHIOPHEN-3-YLBORONIC ACID
BENZO[B]THIOPHENE-3-BORONIC ACID
BENZOTHIOPHENE-3-BORONIC ACID
ASDI-INTER 500027787
THIANAPHTHENE-3-BORONIC ACID
1-Benzothiophen-3-ylboronic acid ,97%
1-Benzothiophen-3-ylboronic acid, May contain varying amounts of anhydride, 97%
Benzo[b]thien-3-ylboronic acid
1-benzothien-3-ylboronic acid(SALTDATA: FREE)
1-Benzo[b]thiophen-3-ylboronic acid
3-Boronobenzo[b]thiophene, 1-Benzothiophene-3-boronic acid, 3-Borono-1-benzothiophene, Thianaphthene-3-boronic acid
Benzo[b]thiophene-3-boronic acid 95+%
Benzothiophene-3-boronic acid
Thianaphthene-3-boronic acid
Thianaphthen-3-ylboronic acid
Benzo[b]thien-3-ylboronic acid >=95.0%
Benzo[b]thiophene-3-boronic Acid (contains varying amounts of Anhydride)
Boronic acid,B-benzo[b]thien-3-yl-
B-Benzo[b]thien-3-ylboronic acid
1-Benzothiophene-3-boronic Acid
Benzo[b]thiophene-3-boronic acid, 97%, contains varying amounts of anhydride
Benzo[b]thiophene-3-boronic Acid (contains varying amounts of Anhydride) >
Benzo[b]thien-3-yL
Benzo[b]thiophen-3-ylboronicaci
Benzothiophene-3-ylboronic acid
Benzo[b]thiophen-3-yl-boronic acid
benzo[b]thiophen-3-ylboronicacid(containsvaryingamountsofAnhydride)
Benzo[b]thien-3-ylboronic acid
113893-08-6
113893-08-06
BORONIC ACID
Heteroaryl
Organometallic Reagents
Boronic Acids and Derivatives
Boronic Acids
Boronic Acids
Boronic Acids and Derivatives
Chemical Synthesis
Heteroaryl Boronic Acids
Organometallic Reagents
blocks
BoronicAcids
Boronic Acids
Boronic Acids and Derivatives
Heteroaryl
