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ChemicalBook >> CAS DataBase List >>(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

CAS No.
148901-68-2
Chemical Name:
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
Synonyms
(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde;PT-4;Pitavastatin acrolein;(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl;3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal;(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-prope;(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-Quinolinyl-2-propenal;(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]prop-2-en-1-al;2-Propenal, 3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-, (2E)-;(E)-3''-[4-(4''-FLUOROPHENYL)-2-(CYCLOPROPYL)-3-QUINOLINYL]-2-PROPENAL
CBNumber:
CB4947383
Molecular Formula:
C21H16FNO
Molecular Weight:
317.36
MDL Number:
MFCD09955496
MOL File:
148901-68-2.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:44
Product description Number Pack Size Price
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 269519 50g $821
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 269519 100g $1204
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 269519 250g $1805
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 269519 500g $2867
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 269519 1g $4047
More product size

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal Properties

Melting point 136-142 °C
Boiling point 491.8±45.0 °C(Predicted)
Density 1.256±0.06 g/cm3(Predicted)
pka 3.82±0.50(Predicted)
CAS DataBase Reference 148901-68-2(CAS DataBase Reference)

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 269519 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 148901-68-2 50g $821 2026-06-03 Buy
Usbiological 269519 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 148901-68-2 100g $1204 2026-06-03 Buy
Usbiological 269519 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 148901-68-2 250g $1805 2026-06-03 Buy
Usbiological 269519 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 148901-68-2 500g $2867 2026-06-03 Buy
Usbiological 269519 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal Asreported 148901-68-2 1g $4047 2026-06-03 Buy
Product number Packaging Price Buy
269519 50g $821 Buy
269519 100g $1204 Buy
269519 250g $1805 Buy
269519 500g $2867 Buy
269519 1g $4047 Buy

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal Chemical Properties,Uses,Production

Synthesis

Cyclohexanamine, N-ethylidene-, [N(E)]-

113832-57-8

2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxaldehyde

121660-37-5

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

148901-68-2

The general procedure for the synthesis of (E)-3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]acrolein from the compound (CAS: 113832-57-8) and 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxaldehyde is as follows: the general procedure is as follows: except for the use of ethylidene cyclohexylamine (1.7 g, 13.8 mmol) in place of the ethylidene tert-butylamine (1.4 g, 14.1 mmol), the operation was the same as in Example 1. A portion of the reaction mixture was poured into 10% (w/v) aqueous acetic acid solution and analyzed by high performance liquid chromatography (HPLC) using the internal standard method. The analytical results showed that (E)-3-[4'-(4"-fluorophenyl)-2'-cyclopropylquinolin-3'-yl]propanal (1.7 g, 5.4 mmol, 78.3% yield) was successfully synthesized.

References

[1] Patent: EP1614682, 2006, A1. Location in patent: Page/Page column 6

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View Lastest Price from (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal pictures 2026-01-04 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
148901-68-2
1KG 99% 500 Hangzhou ICH Biofarm Co., Ltd
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal pictures 2019-07-06 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
148901-68-2
$1.00 1kg 98% 100KG Career Henan Chemical Co
(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-Quinolinyl-2-propenal PT-4 (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]prop-2-en-1-al (E)-3''-[4-(4''-FLUOROPHENYL)-2-(CYCLOPROPYL)-3-QUINOLINYL]-2-PROPENAL 3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal 2-Propenal, 3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-, (2E)- (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-prope (E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde Pitavastatin acrolein 148901-68-2 C21H16FNO Pitavastatin Calcium Intermediates
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