2-Iodo-1,3-dimethylbenzene
- CAS No.
- 608-28-6
- Chemical Name:
- 2-Iodo-1,3-dimethylbenzene
- Synonyms
- 2-IODO-M-XYLENE;2,6-DIMETHYLIODOBENZENE;2-Jod-m-xylol;2-IODO-O-XYLENE;m-Xylene,2-iodo-;m-Xylene, 2-iodo-;I**2-IODO-M-XYLENE;2-Iodo-m-xylene>2-Iodo-m-xylene,98%;Iodo-1,3-diMethylbe
- CBNumber:
- CB5208357
- Molecular Formula:
- C8H9I
- Molecular Weight:
- 232.06
- MDL Number:
- MFCD00019012
- MOL File:
- 608-28-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Iodo-1,3-dimethylbenzene 97% | 596795 | 5g | $95.5 |
| 2-Iodo-m-xylene | I0752 | 5G | $40 |
| 2-Iodo-m-xylene | I0752 | 25G | $158 |
| 2-Iodo-m-xylene | TRC-I729410-5G | 5g | $109 |
| 2-Iodo-m-xylene | TRC-I729410-1G | 1g | $65 |
| More product size | |||
| Melting point | 11.2°C |
|---|---|
| Boiling point | 223-224 °C (lit.) |
| Density | 1.608 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 216 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Clear Pale Yellow |
| Water Solubility | insoluble |
| Sensitive | Light Sensitive |
| BRN | 1857414 |
| InChI | 1S/C8H9I/c1-6-4-3-5-7(2)8(6)9/h3-5H,1-2H3 |
| InChIKey | QTUGGVBKWIYQSS-UHFFFAOYSA-N |
| SMILES | Cc1cccc(C)c1I |
| CAS DataBase Reference | 608-28-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 2-iodo-1,3-dimethyl-(608-28-6) |
| EPA Substance Registry System | Benzene, 2-iodo-1,3-dimethyl- (608-28-6) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H335 | |||||||||
| Precautionary statements | P280-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,C | |||||||||
| Risk Statements | 37/38-41-36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29039990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Iodo-1,3-dimethylbenzene price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 596795 | 2-Iodo-1,3-dimethylbenzene 97% | 608-28-6 | 5g | $95.5 | 2023-06-20 | Buy |
| TCI Chemical | I0752 | 2-Iodo-m-xylene | 608-28-6 | 5G | $40 | 2026-04-30 | Buy |
| TCI Chemical | I0752 | 2-Iodo-m-xylene | 608-28-6 | 25G | $158 | 2026-04-30 | Buy |
| TRC | TRC-I729410-5G | 2-Iodo-m-xylene | 608-28-6 | 5g | $109 | 2026-06-03 | Buy |
| TRC | TRC-I729410-1G | 2-Iodo-m-xylene | 608-28-6 | 1g | $65 | 2026-06-03 | Buy |
2-Iodo-1,3-dimethylbenzene Chemical Properties,Uses,Production
Chemical Properties
clear green-brown to brown liquid
Uses
2-Iodo-m-xylene is used in the preparation of p-(arylethynyl)arylpropanoic acid derivatives as free fatty acid receptor 1 agonists with low lipophilicity and high oral bioavailability.
Synthesis
100379-00-8
608-28-6
General procedure for the synthesis of 2-iodo-1,3-dimethylbenzene using 2,6-dimethylphenylboronic acid as starting material: arylboronic acid (0.5 mmol) and K2CO3 (1 mmol, 138.0 mg) were added to a 20 mL Schlenk tube fitted with a non-magnetic stir bar. The reaction tube was evacuated and filled with nitrogen and this operation was repeated twice. Acetonitrile (2 mL) and iodine (0.75 mmol, 191 mg) were added to the reaction tube at room temperature. The reaction tube was sealed and placed in an oil bath preheated to 80 °C for 8-12 h under nitrogen protection. Upon completion of the reaction, the reaction solution was cooled to room temperature. Water (10 mL) was added for dilution. For the products 2s and 2t, the pH needed to be adjusted to 2 by adding 1 M HCl to the aqueous phase before extraction. the aqueous phase was extracted with ethyl acetate (3 x 5 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated by rotary evaporation. Finally, the residue was purified by silica gel column chromatography to give the target products 2a-v.
References
[1] Synlett, 2014, vol. 25, # 7, p. 995 - 1000
2-Iodo-1,3-dimethylbenzene Preparation Products And Raw materials
Raw materials
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Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
View Lastest Price from 2-Iodo-1,3-dimethylbenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 2-Iodo-1,3-dimethylbenzene
608-28-6
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2026-07-09 | 2-Iodo-1,3-dimethylbenzene
608-28-6
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2022-02-22 | 2-Iodo-1,3-dimethylbenzene
608-28-6
|
1KG | 99.0% | 100 tons | Honest Joy Holdings Limited
|
-
- 2-Iodo-1,3-dimethylbenzene
608-28-6
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 2-Iodo-1,3-dimethylbenzene
608-28-6
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Iodo-1,3-dimethylbenzene
608-28-6
- $0.00
- 99.0%
- Honest Joy Holdings Limited
