3,3-Dimethylbutyryl chloride
- CAS No.
- 7065-46-5
- Chemical Name:
- 3,3-Dimethylbutyryl chloride
- Synonyms
- TBAC;3,3-DIMETHYLBUTANOYL CHLORIDE;TERT-BUTYLACETYL CHLORIDE;T-BUTYLACETYL CHLORIDE;AKOS BBS-00003928;3,3-Dimethylbutyryl;butylacetylchloride;Chloroacetoacetamides;DiMethylbutyryl chlorid;Ter-butylacetyl chloride
- CBNumber:
- CB5249013
- Molecular Formula:
- C6H11ClO
- Molecular Weight:
- 134.6
- MDL Number:
- MFCD00000737
- MOL File:
- 7065-46-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3,3-Dimethylbutyryl chloride 99% | B88802 | 25g | $91.4 |
| 3,3-Dimethylbutyryl chloride 99% | B88802 | 100g | $262 |
| 3,3-Dimethylbutyryl Chloride >99.0%(T) | B1196 | 25mL | $74 |
| 3,3-Dimethylbutyryl Chloride >99.0%(T) | B1196 | 250mL | $325 |
| 3,3-Dimethylbutyryl Chloride | HAA06546 | 100g | $250 |
| More product size | |||
| Boiling point | 127-129 °C (lit.) |
|---|---|
| Density | 0.969 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 70 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Water Solubility | Reacts with water. |
| Sensitive | Moisture Sensitive |
| BRN | 1740421 |
| InChI | InChI=1S/C6H11ClO/c1-6(2,3)4-5(7)8/h4H2,1-3H3 |
| InChIKey | BUTKIHRNYUEGKB-UHFFFAOYSA-N |
| SMILES | C(Cl)(=O)CC(C)(C)C |
| CAS DataBase Reference | 7065-46-5(CAS DataBase Reference) |
| NIST Chemistry Reference | tert-Butyl acetyl chloride(7065-46-5) |
| EPA Substance Registry System | Butanoyl chloride, 3,3-dimethyl- (7065-46-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS02,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H315-H318 | |||||||||
| Precautionary statements | P210-P280-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 10-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 2924 3/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 9-13-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29159000 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Dam. 1 Flam. Liq. 2 Skin Irrit. 2 |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 1.0 L (0.3 gallon) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
3,3-Dimethylbutyryl chloride price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B88802 | 3,3-Dimethylbutyryl chloride 99% | 7065-46-5 | 25g | $91.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | B88802 | 3,3-Dimethylbutyryl chloride 99% | 7065-46-5 | 100g | $262 | 2026-04-30 | Buy |
| TCI Chemical | B1196 | 3,3-Dimethylbutyryl Chloride >99.0%(T) | 7065-46-5 | 25mL | $74 | 2026-04-30 | Buy |
| TCI Chemical | B1196 | 3,3-Dimethylbutyryl Chloride >99.0%(T) | 7065-46-5 | 250mL | $325 | 2026-04-30 | Buy |
| Biosynth | HAA06546 | 3,3-Dimethylbutyryl Chloride | 7065-46-5 | 100g | $250 | 2026-06-04 | Buy |
3,3-Dimethylbutyryl chloride Chemical Properties,Uses,Production
Chemical Properties
Clear colorless to slightly yellow liquid
Uses
3,3-Dimethylbutyryl Chloride is a useful compound in organic synthesis.
Application
3,3-Dimethylbutyryl chloride is a very important acylation reagent, mainly used as a pharmaceutical intermediate.
Synthesis
Add 3,3-dimethylbutyric acid into the reactor, stir, add phosphorus trichloride, raise the temperature to the reaction temperature for reaction, cool to room temperature after the reaction, and stand for stratification; separate after standing for stratification The phosphorous acid in the lower layer is used as a by-product, and the crude acid chloride in the upper layer is collected under reduced pressure distillation at an absolute pressure of 20KPa to collect a fraction at 79-81°C to obtain 3,3-dimethylbutyryl chloride product.
3,3-Dimethylbutyryl chloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaoxing Fangxiao Chemical Co., LTD | +86-13456999252 +86-13868192239 | kenny@fangxiaochem.com | China | 50 | 58 |
| Qi-Chem Co., Ltd. | +86-041188165951 | cristiano.zhang@qi-chem.com | China | 133 | 58 |
| Shijiazhuang Dowell Chemical Co.,Ltd | +8618633820607 | sell@dowechem.com | China | 89 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
View Lastest Price from 3,3-Dimethylbutyryl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-28 | 3,3-Dimethylbutyryl chloride
7065-46-5
|
$10.00 | 1KG | 99.% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
![]() |
2025-09-25 | t-butylacetyl chloride
7065-46-5
|
$8.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
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2025-06-27 | 3,3-Dimethylbutyryl chloride
7065-46-5
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-

- 3,3-Dimethylbutyryl chloride
7065-46-5
- $10.00
- 99.%
- Hebei Chuanghai Biotechnology Co,.LTD
-

- t-butylacetyl chloride
7065-46-5
- $8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 3,3-Dimethylbutyryl chloride
7065-46-5
- $0.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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